Results 211 to 220 of about 9,303,187 (361)

Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas

Advanced Materials, EarlyView.
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac, Luv Patel, Nguyen Tran, Amarnath Singam, DongSoo Yun, Prasun Guha, Seungman Park, Chandrabali Bhattacharya   +7 more
wiley   +1 more source

Computational and Experimental Analysis of Drug‐Coated Microneedle Skin Insertion: The Mode of Administration Matters

Advanced Materials Interfaces, EarlyView.
This study investigates how the mode of application affects drug delivery from coated microneedles. Combining finite element modeling with custom 3D‐printed Franz Diffusion Cells, the researchers found that prolonged application pressure from microneedles in situ reduces drug permeation.
Wenting Shu, Thomas Lijnse, Fiona McCartney, David J. Brayden, Aisling Ní Annaidh, Eoin D. O'Cearbhaill   +5 more
wiley   +1 more source

Chronic Care for Neglected Infectious Diseases: Leprosy/Hansen's Disease, Lymphatic Filariasis, Trachoma, and Chagas Disease

, 2021
Pan American Health Organization
openalex   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Prevalence and patterns of multiple long-term conditions among lymphatic filariasis patients in Odisha, India: a community-based cross-sectional study. [PDF]

BMC Public Health
Sinha A, Sahoo PK, Sahoo KC, Highton P, Mohanty S, Nayak T, Prusty AK, Choudhury S, Kumari B, Puchner K, Khunti K, Pati S.   +11 more
europepmc   +1 more source

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

EBUS/EUS-guided lymph nodal gadolinium injection and MRI of the chest in diagnosis of abnormal lymphatic drainage. A case series. [PDF]

Sarcoidosis Vasc Diffuse Lung Dis
Poletti V, Petrarulo S, Giampalma E, Ravaglia C, Piciucchi S.   +4 more
europepmc   +1 more source

Altered Circulating Levels of Matrix Metalloproteinases and Inhibitors Associated with Elevated Type 2 Cytokines in Lymphatic Filarial Disease

, 2012
Anuradha Rajamanickam, Jovvian P. George, Nathella Pavankumar, V. Kumaraswami, Thomas B. Nutman, Subash Babu   +5 more
openalex   +2 more sources

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

Epidemiological assessment of neglected diseases in children: lymphatic filariasis and soil-transmitted helminthiasis

, 2013
Ana Maria Aguiar-Santos, Zulma Medeiros, Cristine Vieira do Bonfim, Abraham Rocha, Eduardo Brandão, Tereza Miranda, Paula Oliveira, Emanuel S.C. Sarinho   +7 more
openalex   +1 more source