Results 31 to 40 of about 119,650 (284)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

From the discovery to the future of the lymphatic system: a virtual interview with Gaspare Aselli

Veins and Lymphatics
Not available.
Alberto Macciò
doaj   +3 more sources

Computer-assisted vacuum aspiration mechanical thrombectomy with Lightning Flash allows broader clinical application, enhanced procedural safety, and improved clinical outcomes for the treatment of acute and subacute iliofemoral and central deep venous thrombosis

Journal of Vascular Surgery Cases and Innovative Techniques
We describe our experience with the 16F Lightning Flash vacuum aspiration mechanical thrombectomy system in 25 patients. All patients were treated in a single session with a mean estimated blood loss of 60 mL.
Taimur Saleem, MD, FACS, Seshadri Raju, MD, FACS   +1 more
doaj   +1 more source

Enfermedad de Kikuchi-Fujimoto: presentación de un caso pediátrico

Biomédica: revista del Instituto Nacional de Salud, 2010
La enfermedad de Kikuchi-Fujimoto, o linfadenitis necrosante histiocítica, es una afección benigna, poco frecuente, generalmente de resolución espontánea, en un periodo de seis meses. La presentación clínica característica incluye linfadenopatía cervical,
Carolina Gómez, Ruth María Eraso, Carlos A. Aguirre, María del Pilar Pérez   +3 more
doaj   +1 more source

TGF-β signaling in lymphatic vascular vessel formation and maintenance

Frontiers in Physiology, 2022
Transforming growth factor (TGF)-β and its family members, including bone morphogenetic proteins (BMPs), nodal proteins, and activins, are implicated in the development and maintenance of various organs. Here, we review its role in the lymphatic vascular
Fumiko Itoh, Tetsuro Watabe
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

RevCore thrombectomy device effectively restores venous stent patency by treating iliofemoral caval in-stent restenosis

Journal of Vascular Surgery Cases and Innovative Techniques
Experience with the RevCore mechanical thrombectomy device in a series of 40 patients is described. The device was employed in the treatment of symptomatic in-stent restenosis (ISR) in iliofemoral caval venous stents in these patients.
Taimur Saleem, MD, FACS, Seshadri Raju, MD, FACS   +1 more
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Proximal ligation after the side-to-end anastomosis recovery technique for lymphaticovenous anastomosis

Archives of Plastic Surgery, 2019
Background Lymphaticovenous anastomosis is an important surgical treatment for lymphedema, with lymphaticovenous side-to-end anastomosis (LVSEA) and lymphaticovenous end-to-end anastomosis being the most frequently performed procedures.
Yushi Suzuki, Hisashi Sakuma, Jun Ihara, Yusuke Shimizu   +3 more
doaj   +1 more source

Lymphatic vessels in health and disease [PDF]

WIREs Systems Biology and Medicine, 2012
AbstractThe lymphatic vasculature plays vital roles in tissue fluid balance, immune defense, metabolism, and cancer metastasis. In adults, lymphatic vessel formation and remodeling occur primarily during inflammation, development of the corpus luteum, wound healing, and tumor growth.
Cristina T, Kesler, Shan, Liao, Lance L, Munn, Timothy P, Padera   +3 more
openaire   +2 more sources