Results 51 to 60 of about 127,851 (297)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The impact of mass drug administration and long-lasting insecticidal net distribution on Wuchereria bancrofti infection in humans and mosquitoes: an observational study in northern Uganda. [PDF]

, 2011
BACKGROUND: Lymphatic filariasis (LF) in Uganda is caused by Wuchereria bancrofti and transmitted by anopheline mosquitoes. The mainstay of elimination has been annual mass drug administration (MDA) with ivermectin and albendazole, targeted to endemic ...
Ambrose Onapa, Opio, Tom, Tansy Edwards, Brooker, Simon, Kolaczinski, Jan H, Tom Opio, Ashton, Ruth A, Simon Brooker, Daniel J Kyabayinze, Jan H Kolaczinski, Kyabayinze, Daniel J, Ruth A Ashton, Onapa, Ambrose, Edwards, Tansy, Gabriel Matwale, Auma, Anna, Matwale, Gabriel, Anna Auma   +17 more
core   +1 more source

Supporting drug development for neglected tropical diseases using mathematical modelling [PDF]

, 2021
Drug-based interventions are at the heart of global efforts to reach elimination as a public health problem (trachoma, soil-transmitted helminthiases, schistosomiasis, lymphatic filariasis) or elimination of transmission (onchocerciasis) for five of the ...
Basanez, Maria-Gloria, Hamley, Jonathan, Kinrade, Sally, Pedrique, Belen, Milton, Philip, Walker, Martin, Hamley, Jonathan I D, Specht, Sabine, Monnot, Frédéric, Monnot, Frederick   +9 more
core   +1 more source

Research Progress on Intracranial Lymphatic Circulation and Its Involvement in Disorders

Frontiers in Neurology, 2022
The lymphatic system is an important part of the circulatory system, as an auxiliary system of the vein, which has the functions of immune defense, maintaining the stability of the internal environment, and regulating the pressure of the tissue.
Fan Chen, Xuan Xie, Liang Wang
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Value of investing in neglected tropical diseases : an investment case for the elimination and eradication of onchocerciasis (river blindness) [PDF]

, 2015
Elimination of neglected tropical diseases (NTDs) has emerged on the global agenda. This PhD research developed an investment case for the elimination and eradication of onchocerciasis (river blindness) which is one of the NTDs endemic in Africa.
Kim, Young Eun
core   +1 more source

From the discovery to the future of the lymphatic system: a virtual interview with Gaspare Aselli

Veins and Lymphatics
Not available.
Alberto Macciò
doaj   +3 more sources

Lymphatic endothelium in health and disease [PDF]

Cell and Tissue Research, 2008
ISSN:1432 ...
Jurisic, Giorgia, Detmar, Michael
openaire   +4 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Dynamic Contrast-Enhanced Magnetic Resonance Lymphangiography and Lymphatic Interventions for Pediatric Patients with Various Lymphatic Diseases

, 2023
Background: To demonstrate the magnetic resonance lymphangiography (MRL) imaging findings of lymphatic diseases and the clinical outcomes of lymphatic embolization in pediatric patients.
Yura Ahn, Myung-Hee Song, Dong Hyun Yang, Hyun Jung Koo, Eun-Young Joo, Joon-Won Kang, Ji Hoon Shin, Hee Mang Yoon, Jooae Choe   +8 more
core   +1 more source