Results 51 to 60 of about 199,212 (293)

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Computer-assisted vacuum aspiration mechanical thrombectomy with Lightning Flash allows broader clinical application, enhanced procedural safety, and improved clinical outcomes for the treatment of acute and subacute iliofemoral and central deep venous thrombosis

Journal of Vascular Surgery Cases and Innovative Techniques
We describe our experience with the 16F Lightning Flash vacuum aspiration mechanical thrombectomy system in 25 patients. All patients were treated in a single session with a mean estimated blood loss of 60 mL.
Taimur Saleem, MD, FACS, Seshadri Raju, MD, FACS   +1 more
doaj   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Novel application assigned to toluquinol: inhibition of lymphangiogenesis by interfering with VEGF-C/VEGFR-3 signalling pathway [PDF]

, 2016
BACKGROUND AND PURPOSE Lymphangiogenesis is an important biological process associated with the pathogenesis of several diseases, including metastatic dissemination, graft rejection, lymphoedema and other inflammatory disorders.
Blacher, S., García-Caballero, Melissa, Medina, Miguel Ángel, Nöel, Agnes, Pauper, J., Quesada, Ana R.   +5 more
core  

Update on the current status of onchocerciasis in Cote d’Ivoire following 40 years of intervention: Progress and challenges [PDF]

, 2018
Background Onchocerciasis control in Côte d’Ivoire started with aerial insecticide spraying in 1974 and continued with community directed treatment with ivermectin (CDTi) from 1992 to the present.
Aba, Elvis, Brika, Pierre, Fischer, Peter U, King, Christopher L, Kouakou, Marie-Madeleine, Kouakou, Roger, Koudou, Benjamin G, Meite, Aboulaye, Ouattara, Allassane F, Weil, Gary J, Yeo, Souleymane   +10 more
core   +4 more sources

RevCore thrombectomy device effectively restores venous stent patency by treating iliofemoral caval in-stent restenosis

Journal of Vascular Surgery Cases and Innovative Techniques
Experience with the RevCore mechanical thrombectomy device in a series of 40 patients is described. The device was employed in the treatment of symptomatic in-stent restenosis (ISR) in iliofemoral caval venous stents in these patients.
Taimur Saleem, MD, FACS, Seshadri Raju, MD, FACS   +1 more
doaj   +1 more source

TGF-β signaling in lymphatic vascular vessel formation and maintenance

Frontiers in Physiology, 2022
Transforming growth factor (TGF)-β and its family members, including bone morphogenetic proteins (BMPs), nodal proteins, and activins, are implicated in the development and maintenance of various organs. Here, we review its role in the lymphatic vascular
Fumiko Itoh, Tetsuro Watabe
doaj   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

Spatial distribution of podoconiosis in relation to environmental factors in Ethiopia: a historical review [PDF]

, 2013
BACKGROUND An up-to-date and reliable map of podoconiosis is needed to design geographically targeted and cost-effective intervention in Ethiopia.
Abdisalan Mohamed Noor, AC Clements, Asrat Hailu, AW Onapa, C Sikorski, D Frommel, DH Molyneux, DH Molyneux, E Price, EW Price, EW Price, EW Price, EW Price, EW Price, EW Price, EW Price, F de Lalla, F Tekola, Fikre Enquselassie, G Alemu, G Davey, G Davey, G Davey, G Mengistu, Gail Davey, GG Oli, H Birrie, H Kloos, HH Weinert, JM Macé, JO Gyapong, JO Gyapong, K Deribe, K Desta, Kebede Deribe, Melanie Newport, MK Saunders, P Crivelli, Rachel L. Pullan, Richard Reithinger, RJ Hijmans, RL Pullan, S Brooker, S Wanji, S Wanji, Simon J. Brooker, SM Njenga, W Shiferaw, YB Molla   +48 more
core   +3 more sources

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source