Results 61 to 70 of about 2,612,610 (300)

Lymphatic endothelium in health and disease [PDF]

open access: yesCell and Tissue Research, 2008
The lymphatic vascular system has an important role in the maintenance of tissue fluid pressure homeostasis, in the mediation of the afferent immune response via recruitment of antigen-presenting cells toward draining lymph nodes, and in the intestinal absorption of dietary lipids.
Jurisic, Giorgia, Detmar, Michael
openaire   +4 more sources

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Supporting drug development for neglected tropical diseases using mathematical modelling [PDF]

open access: yes, 2021
Drug-based interventions are at the heart of global efforts to reach elimination as a public health problem (trachoma, soil-transmitted helminthiases, schistosomiasis, lymphatic filariasis) or elimination of transmission (onchocerciasis) for five of the ...
Basanez, Maria-Gloria   +17 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Outcomes Following Iliac Vein Stenting for Non-Thrombotic Iliac Vein Lesions—A Narrative Review Based on Large Sample Studies

open access: yesJournal of Functional Biomaterials
Objective: May–Thurner syndrome typically refers to symptoms and signs arising from the compression of the left common iliac vein by the right common iliac artery. However, such clinical manifestations can occur in the setting of compression of the right
Arjun Jayaraj
doaj   +1 more source

Enfermedad de Kikuchi-Fujimoto: presentación de un caso pediátrico

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2010
La enfermedad de Kikuchi-Fujimoto, o linfadenitis necrosante histiocítica, es una afección benigna, poco frecuente, generalmente de resolución espontánea, en un periodo de seis meses. La presentación clínica característica incluye linfadenopatía cervical,
Carolina Gómez   +3 more
doaj   +1 more source

Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures [PDF]

open access: yes, 2013
Insertion of bone substitution materials accelerates healing of osteoporotic fractures. Biodegradable materials are preferred for application in osteoporotic patients to avoid a second surgery for implant replacement. Degraded implant fragments are often
Vivien Kauschke   +50 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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