Results 61 to 70 of about 9,431,933 (366)
Research Progress on Intracranial Lymphatic Circulation and Its Involvement in Disorders
Frontiers in Neurology, 2022 The lymphatic system is an important part of the circulatory system, as an auxiliary system of the vein, which has the functions of immune defense, maintaining the stability of the internal environment, and regulating the pressure of the tissue.
Fan Chen, Xuan Xie, Liang Wang
doaj +1 more source
The therapeutic efficacy and macrofilaricidal activity of doxycycline for the treatment of river blindness [PDF]
, 2014 Background. Onchocerca volvulus and lymphatic filariae, causing river blindness and elephantiasis, depend on endosymbiotic Wolbachia bacteria for growth, development, fertility, and survival.
Achim Hoerauf +43 more
core +2 more sources
Most of the response elicited against Wolbachia surface protein in filarial nematode infection is due to the infective larval stage [PDF]
, 2004 Immune responses to the intracellular Wolbachia bacteria of filarial nematodes are thought to contribute to the pathologic process of filarial infection.
Allen, Judith E +7 more
core +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
TGF-β signaling in lymphatic vascular vessel formation and maintenance
Frontiers in Physiology, 2022 Transforming growth factor (TGF)-β and its family members, including bone morphogenetic proteins (BMPs), nodal proteins, and activins, are implicated in the development and maintenance of various organs. Here, we review its role in the lymphatic vascular
Fumiko Itoh, Tetsuro Watabe
doaj +1 more source
Regulation of VEGFR Signalling in Lymphatic Vascular Development and Disease: An Update
International Journal of Molecular Sciences, 2021 The importance of lymphatic vessels in a myriad of human diseases is rapidly gaining recognition; lymphatic vessel dysfunction is a feature of disorders including congenital lymphatic anomalies, primary lymphoedema and obesity, while improved lymphatic ...
G. Secker, N. Harvey
semanticscholar +1 more source
FEBS Letters, EarlyView.C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi +5 more
wiley +1 more source
Enfermedad de Kikuchi-Fujimoto: presentación de un caso pediátrico
Biomédica: revista del Instituto Nacional de Salud, 2010 La enfermedad de Kikuchi-Fujimoto, o linfadenitis necrosante histiocítica, es una afección benigna, poco frecuente, generalmente de resolución espontánea, en un periodo de seis meses. La presentación clínica característica incluye linfadenopatía cervical,
Carolina Gómez +3 more
doaj +1 more source
Meningeal lymphatic vessels regulate brain tumor drainage and immunity
Cell Research, 2020 Recent studies have shown that meningeal lymphatic vessels (MLVs), which are located both dorsally and basally beneath the skull, provide a route for draining macromolecules and trafficking immune cells from the central nervous system (CNS) into cervical
Xueting Hu +21 more
semanticscholar +1 more source
Microcirculation, 2021 Lymphatic vessels (LVs) maintain fluid homeostasis by draining interstitial fluid. A failure in lymphatic drainage triggers lymphatic diseases such as lymphedema.
A. Henderson, Isabelle S. Ilan, Esak Lee
semanticscholar +1 more source