TGFß1 Stimulates Lymphatic Endothelial Cells to Produce IL7 and IL15, Which Act as Chemotactic Factors for Breast Cancer Cells with Mesenchymal Properties. [PDF]
Giotopoulou N+4 more
europepmc +1 more source
This study determines the maximum tolerated dose of lenvatinib in combination with paclitaxel as second‐line therapy for advanced gastric cancer patients. A dynamic network biomarker panel associated with patient prognosis and response to treatment is established.
Chenfei Zhou+8 more
wiley +1 more source
Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1/CD31) and CD99 Are Critical in Lymphatic Transmigration of Human Dendritic Cells [PDF]
Martin Torzicky+6 more
openalex +1 more source
Cancer Neuroscience: Decoding Neural Circuitry in Tumor Evolution for Targeted Therapy
This review highlights the pivotal role of the nervous system in cancer progression, emphasizing how neural–tumor interactions—via synaptic signaling, neurotransmitters, and paracrine factors—reshape the tumor microenvironment. It introduces cancer neuroscience as an emerging field and proposes integrating advanced tools such as AI and optogenetics to ...
Mengyu Yuan+4 more
wiley +1 more source
Axillary adipose tissue-derived lymphatic endothelial cells exhibit distinct transcriptomic signatures reflecting lymphatic invasion status in breast cancer. [PDF]
Iesato A+20 more
europepmc +1 more source
Cancer-associated fibroblast-derived PAI-1 promotes lymphatic metastasis via the induction of EndoMT in lymphatic endothelial cells. [PDF]
Wei WF+10 more
europepmc +1 more source
In KRAS‐mutant tumors, KRAS transcriptionally upregulates COA4 via the PI3K/AKT/E2F1 axis, promoting metastasis. Mechanistically, COA4 enhances tumor cell migration through dual pathways: within mitochondria, it boosts oxidative phosphorylation; in the cytoplasm, it binds and activates CDC42 to stimulate pseudopodia formation.
Xingzhao Ji+14 more
wiley +1 more source
Effect of Oxymatrine Combined with Low Dose 5-FU on Lymphatic Vessel and Microvascular Endothelial Cell Growth of Gastric Cancer in a Severe Combined Immunodeficient Mouse Orthotopic Implantation Model [PDF]
J-S. Zhu, Z.-P. Xu, M-Q. Song, Q. Zhang
openalex +1 more source
Molecules That Have Rarely Been Studied in Lymphatic Endothelial Cells. [PDF]
Becker J, Wilting J.
europepmc +1 more source