Results 231 to 240 of about 5,011,546 (295)

Mapping Tumor Recurrence and Metastasis With Pan‐Cancer Multi‐Omics

open access: yesMed Research, EarlyView.
Tumor recurrence and metastasis arise from the interaction of shared evolutionary programs and context‐dependent modifiers. Clonal evolution, including genomic instability, subclonal selection, and treatment pressure, interacts with reversible cell‐state plasticity involving partial EMT, stemness, and dormancy, whereas immune escape, stromal remodeling,
Wenjun Meng   +13 more
wiley   +1 more source

Pink Polypoid Papulo‐Vesicles on Labia Majora

open access: yes
JEADV Clinical Practice, EarlyView.
Maria Chiara Mercuri   +3 more
wiley   +1 more source

Recent Advances in Cryogel Applications for Musculoskeletal Regeneration

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim   +4 more
wiley   +1 more source

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo   +4 more
wiley   +1 more source

SHP2 in Cancer: From Tumor Biology to Therapeutic Targeting

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT SHP2 is a tyrosine phosphatase that mediates intracellular signaling downstream of transmembrane receptors regulated by a pair of src homology 2 (SH2) domains. Its overexpression and mutation are pivotal in driving tumor progression by influencing various cancer's fundamental characteristics, such as metastasis, DNA repair, angiogenesis ...
Maryam Jama   +2 more
wiley   +1 more source

Therapeutic Interventions for Radiation‐Induced Fibrosis in Head and Neck Cancer Patients: A Systematic Review

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To review and evaluate treatments for radiation‐induced fibrosis (RIF) following head and neck cancer (HNC) therapy. Data sources Medline, Embase.com, Web of Science, and Cochrane Library. Review Methods A systematic review was conducted on the management of HNC RIF using the Preferred Reporting Items for Systematic Reviews and Meta ...
Pooja D. Reddy   +6 more
wiley   +1 more source

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