Results 51 to 60 of about 21,127 (198)

Helminths as architects of trained tolerance: implications for human health

Clinical &Translational Immunology, Volume 15, Issue 3, 2026.
Abstract Helminths infect nearly 2 billion people worldwide and are a major cause of chronic morbidity in low‐resource regions. Unlike bacterial and viral pathogens that elicit protective memory, helminths actively remodel host immunity to enable their years‐long persistence and reinfection.
Quinn Moroz, Jorge Lucas Nascimento Souza, Neima Briggs   +2 more
wiley   +1 more source

Current perspective of new anti-Wolbachial and direct-acting macrofilaricidal drugs as treatment strategies for human filariasis

GMS Infectious Diseases, 2022
Filarial diseases like lymphatic filariasis and onchocerciasis belong to the Neglected Tropical Diseases and remain a public health problem in endemic countries.
Ehrens, Alexandra, Hoerauf, Achim, Hübner, Marc P.   +2 more
doaj   +1 more source

Trends and Patterns of Adverse Drug Reaction Reporting in Sierra Leone: A Retrospective Analysis of VigiFlow Data (2008–2022)

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 3, March 2026.
ABSTRACT Purpose Adverse drug reactions (ADRs) present significant obstacles for healthcare systems, impacting both patient safety and the effectiveness of treatments. Despite this, there is a scarcity of research on ADR reports in Sierra Leone, especially over long periods.
Isatu Jalloh, Onome Thomas Abiri, Peter Bai James, Rajesh Vagiri, Neelaveni Padayachee   +4 more
wiley   +1 more source

Lymphangiogram of a case of presumed lymphatic filariasis with left-sided cisterna chyli

Radiology Case Reports
Lymphatic filariasis is an uncommon condition in Hong Kong and is currently considered as one of the neglected tropical diseases by the World Health Organization. Blood tests are available for diagnosis of acute infections, but false negative results can
Siu Fung Mak, MBBS, FRCR, Kar Ho Lee, MBChB, FRCR, FHKCR, FHKAM, Hing Yan Danny Cho, MBBS, FRCR, FHKCR, FHKAM   +2 more
doaj   +1 more source

Evaluating context-specific evidence-based quality improvement intervention on lymphatic filariasis mass drug administration in Northern Ghana using the RE-AIM framework

Tropical Medicine and Health, 2021
Background Over a decade of implementing a global strategy to eliminate lymphatic filariasis in Ghana through mass drug administration, the disease is still being transmitted in 11 districts out of an initial 98 endemic districts identified in 2000.
Alfred Kwesi Manyeh, Tobias Chirwa, Rohit Ramaswamy, Frank Baiden, Latifat Ibisomi   +4 more
doaj   +1 more source

Tolerability, Safety, and Pharmacokinetics of Ivermectin After Nasal Application in Healthy Adult Subjects

The Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Nasal epithelium is the site of infection for SARS‐CoV2 viruses, with interactions of the viral spike protein with the ACE2 receptor of the host cell. Molecular docking studies have shown that ivermectin shields the spike protein and thereby prevents binding to ACE2.
Stefan Wissel, Philipp Wissel, Matthias Rischer, Felix Häberlein, Hilde Riethmüller‐Winzen, Hanns Häberlein   +5 more
wiley   +1 more source

Prevalence of soil-transmitted helminth infections, schistosomiasis, and lymphatic filariasis before and after preventive chemotherapy initiation in the Philippines: A systematic review and meta-analysis.

PLoS Neglected Tropical Diseases, 2021
ObjectiveTo estimate the impact of preventive chemotherapy on the prevalence and intensity of soil-transmitted helminth (STH) infections, schistosomiasis, and lymphatic filariasis in the Philippines, using systematic review and meta-analysis.MethodsWe ...
John Paul Caesar Robles Delos Trinos, Luh Putu Lila Wulandari, Naomi Clarke, Vicente Belizario, John Kaldor, Susana Vaz Nery   +5 more
doaj   +1 more source

The General Biological Relativity Theory and Multiscale Modeling of Living Systems as Complex Systems

Complexity, Volume 2026, Issue 1, 2026.
The scientific community is aware that the great scientific revolution of this century will be the formulation of a theory of complex systems and formalize it in mathematical terms. In this article, we formulate a unified theory of living systems as complex systems called the general biological relativity theory, which states that at every level of ...
Winston Garira, Bothwell Maregere, Lingzhong Guo   +2 more
wiley   +1 more source

The TLR2/6 ligand PAM2CSK4 is a Th2 polarizing adjuvant in Leishmania major and Brugia malayi murine vaccine models. [PDF]

, 2016
Toll-like receptors (TLRs) play an important role in the innate and adaptive immune responses to pathogens, and are the target of new vaccine adjuvants.
Bates, PA, Guimarães, A, Halliday, A, Taylor, MJ, Turner, JD   +4 more
core   +7 more sources

A Rare Presentation of Scrotal Lymphangioma Circumscriptum: Case Report and Review of Literature

Case Reports in Dermatological Medicine, Volume 2026, Issue 1, 2026.
Lymphangioma circumscriptum (LC) is a rare benign lymphatic malformation of deep dermis and subcutaneous layer. Although it commonly affects the trunk, axilla, thighs, and oral cavity, its appearance in the scrotum is extremely rare and can lead to considerable psychological distress, often due to concerns regarding sexually transmitted infections.
Deeptara Pathak Thapa, Mohan Bhusal, Joshana Shrestha, Smriti Piya, Semonti Nandi   +4 more
wiley   +1 more source