Results 31 to 40 of about 1,572 (116)

Soil-transmitted helminthiasis in four districts in Bangladesh: household cluster surveys of prevalence and intervention status

BMC Public Health, 2020
Background In 2016, after 8 years of twice-annual nationwide preventive chemotherapy (PC) administration to school-age children (SAC), the Bangladesh Ministry of Health & Family Welfare (MOHFW) sought improved impact and intervention monitoring data to ...
Stacy L. Davlin, Alexander H. Jones, Sanya Tahmina, Abdullah Al Kawsar, Anand Joshi, Sazid I. Zaman, Muhammad M. Rahman, Bozena M. Morawski, Michael S. Deming, Rubina Imtiaz, Mohammad J. Karim   +10 more
doaj   +1 more source

Mechanistic‐Statistical Inference of Mosquito Dynamics From Mark‐Release‐Recapture Data

Population Ecology, Volume 68, Issue 3, July 2026.
Mark‐release‐recapture data contain valuable information on mosquito dispersal and survival, but this information is only indirectly observed through trap counts. We combine a mechanistic diffusion model with a statistical observation model to infer movement, mortality, and trap efficiency jointly.
Nga Nguyen, Olivier Bonnefon, René Gato, Luis Almeida, Lionel Roques   +4 more
wiley   +1 more source

Safety and immunogenicity of an adjuvanted human onchocerciasis vaccine candidate, OvMANE1: preclinical evaluation in a mice model

Clinical &Translational Immunology, Volume 15, Issue 7, 2026.
OvMANE1 formulated with Freund's adjuvant was safe and elicited strong humoral and cellular immune responses, including significant IgG and leukocyte activation. These findings highlight OvMANE1 as a promising multi‐epitope vaccine candidate for advancing onchocerciasis prevention.
Derrick Neba Nebangwa, Mary Teke Efeti, Sonia M. E. Momnougui, Cabirou Mounchili Shintouo, Robert Adamu Shey, Rene Bilingwe Ayiseh, Fidele Ntie‐Kang, Stephen Mbigha Ghogomu   +7 more
wiley   +1 more source

Coverage evaluation of mass drug administration for lymphatic filariasis in Bidar district, Karnataka, India

Indian Journal of Community and Family Medicine, 2015
Background: Lymphatic filariasis is one of the oldest and most debilitating of all the neglected tropical diseases. To interrupt transmission of this disease and to eliminate lymphatic filariasis as a public-health problem by 2020, WHO recommends annual ...
H S Ravish, Malatesh Undi, A R Rachana
doaj   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione, Ana Talamillo, Juan M. Falcón‐Pérez   +2 more
wiley   +1 more source

Current perspective of new anti-Wolbachial and direct-acting macrofilaricidal drugs as treatment strategies for human filariasis

GMS Infectious Diseases, 2022
Filarial diseases like lymphatic filariasis and onchocerciasis belong to the Neglected Tropical Diseases and remain a public health problem in endemic countries.
Ehrens, Alexandra, Hoerauf, Achim, Hübner, Marc P.   +2 more
doaj   +1 more source

Critical role of keratinocytes and protease‐activated receptor 2 in secondary lymphedema development

Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.
Activated keratinocytes play an important role in the early stage of the pathophysiology of secondary lymphedema through PAR2 signaling. Lymphatic injury‐induced protease activation stimulates keratinocyte PAR2 signaling, driving hyperkeratosis and Th2 inflammation, which can be therapeutically attenuated by teriflunomide. Abstract Background Secondary
Hyeung Ju Park, Sarit Pal, Xizhao Chen, Jinyeon Shin, Gabriela D. García Nores, Jung Eun Baik, Annica Stull‐Lane, Abraham J. Book, Cristina C. Clement, Elizabeth M. Encarnacion, Mark G. Klang, Elyn Riedel, Tafadzwa L. Chaunzwa, Geoffrey E. Hespe, Laura Santambrogio, Michelle Coriddi, Joseph H. Dayan, Babak J. Mehrara, Raghu P. Kataru   +18 more
wiley   +1 more source

Lymphangiogram of a case of presumed lymphatic filariasis with left-sided cisterna chyli

Radiology Case Reports
Lymphatic filariasis is an uncommon condition in Hong Kong and is currently considered as one of the neglected tropical diseases by the World Health Organization. Blood tests are available for diagnosis of acute infections, but false negative results can
Siu Fung Mak, MBBS, FRCR, Kar Ho Lee, MBChB, FRCR, FHKCR, FHKAM, Hing Yan Danny Cho, MBBS, FRCR, FHKCR, FHKAM   +2 more
doaj   +1 more source

Evaluating context-specific evidence-based quality improvement intervention on lymphatic filariasis mass drug administration in Northern Ghana using the RE-AIM framework

Tropical Medicine and Health, 2021
Background Over a decade of implementing a global strategy to eliminate lymphatic filariasis in Ghana through mass drug administration, the disease is still being transmitted in 11 districts out of an initial 98 endemic districts identified in 2000.
Alfred Kwesi Manyeh, Tobias Chirwa, Rohit Ramaswamy, Frank Baiden, Latifat Ibisomi   +4 more
doaj   +1 more source

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management

Journal of Applied Toxicology, Volume 46, Issue 6, Page 1856-1870, June 2026.
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz, Bayram Göktaş, İlker Ateş, Mustafa Çelik   +3 more
wiley   +1 more source