Results 41 to 50 of about 60,961 (170)

Proinflammatory Cytokine Gene Expression by Murine Macrophages in Response to Brugia malayi Wolbachia Surface Protein

Mediators of Inflammation, 2007
Wolbachia, an endosymbiotic bacterium found in most species of filarial parasites, is thought to play a significant role in inducing innate inflammatory responses in lymphatic filariasis
Chantima Porksakorn, Surang Nuchprayoon, Kiwon Park, Alan L. Scott   +3 more
doaj   +1 more source

Assay strategies for the discovery and validation of therapeutics targeting Brugia pahangi Hsp90 [PDF]

, 2010
The chemotherapy of lymphatic filariasis relies upon drugs such as diethylcarbamazine and ivermectin that largely target the microfilarial stages of the parasite, necessitating continued treatment over the long reproductive life span of the adult worm ...
Gillan, V., O'Neill, K., Devaney, E., Chiosis Gabriela, Kerry O'Neill, Taldone, T., Devaney Eileen, Taldone Tony, Patel, P., O'Neill Kerry, Rodina, A., Kirsty Maitland, Chiosis, G., Maitland Kirsty, Anna Rodina, Rodina Anna, Victoria Gillan, Tony Taldone, Pallav Patel, Gillan Victoria, Sun, W., Eileen Devaney, Patel Pallav, Weilin Sun, Gabriela Chiosis, Maitland, K., Sun Weilin   +26 more
core   +2 more sources

Host, vector, and parasite dynamics: exploring intrinsic and extrinsic factors shaping tick‐borne filarial nematode transmission

Biological Reviews, Volume 101, Issue 4, Page 1779-1792, August 2026.
ABSTRACT Tick‐borne filarial nematodes are a complex and understudied group of parasites that rely on ticks for transmission in vertebrates. This review examines how intrinsic and extrinsic factors may influence the successful transmission of filarial nematodes in tick vectors, drawing insights from extensively studied haematophagous dipteran vector ...
Oluwaseun D. Ajileye, Gabriel L. Hamer, Sarah A. Hamer, Guilherme G. Verocai, Jessica E. Light   +4 more
wiley   +1 more source

Coverage evaluation of mass drug administration for lymphatic filariasis in Bidar district, Karnataka, India

Indian Journal of Community and Family Medicine, 2015
Background: Lymphatic filariasis is one of the oldest and most debilitating of all the neglected tropical diseases. To interrupt transmission of this disease and to eliminate lymphatic filariasis as a public-health problem by 2020, WHO recommends annual ...
H S Ravish, Malatesh Undi, A R Rachana
doaj   +1 more source

Diversity and Distribution Patterns of Insects in Nigeria: A GBIF‐Based Appraisal

Ecology and Evolution, Volume 16, Issue 8, August 2026.
Insect diversity in Nigeria is high, with 5880 species. Diversity differs between biomes. Current diversity represents ~21 of the estimated ‘true’ diversity. ABSTRACT Insects provide essential ecosystem services and are key indicators of ecosystem health.
Emelie Obi, Mikaelison da Silva Lima, Kelechi Amadi, Maduamaka C. Abajue   +3 more
wiley   +1 more source

Urban Lymphatic Filariasis in the Metropolis of\ud Dar es Salaam, Tanzania [PDF]

, 2013
The last decades have seen a considerable increase in urbanization in Sub-Saharan Africa, and it is estimated that over 50% of the population will live in urban areas by 2040.
Simonsen, Paul E, Pedersen, Erling M, Mosha, Franklin W, Mwakitalu, Mbutolwe E, Malecela, Mwelecele N   +4 more
core  

Current perspective of new anti-Wolbachial and direct-acting macrofilaricidal drugs as treatment strategies for human filariasis

GMS Infectious Diseases, 2022
Filarial diseases like lymphatic filariasis and onchocerciasis belong to the Neglected Tropical Diseases and remain a public health problem in endemic countries.
Ehrens, Alexandra, Hoerauf, Achim, Hübner, Marc P.   +2 more
doaj   +1 more source

Mechanistic‐Statistical Inference of Mosquito Dynamics From Mark‐Release‐Recapture Data

Population Ecology, Volume 68, Issue 3, July 2026.
Mark‐release‐recapture data contain valuable information on mosquito dispersal and survival, but this information is only indirectly observed through trap counts. We combine a mechanistic diffusion model with a statistical observation model to infer movement, mortality, and trap efficiency jointly.
Nga Nguyen, Olivier Bonnefon, René Gato, Luis Almeida, Lionel Roques   +4 more
wiley   +1 more source

Evaluating context-specific evidence-based quality improvement intervention on lymphatic filariasis mass drug administration in Northern Ghana using the RE-AIM framework

Tropical Medicine and Health, 2021
Background Over a decade of implementing a global strategy to eliminate lymphatic filariasis in Ghana through mass drug administration, the disease is still being transmitted in 11 districts out of an initial 98 endemic districts identified in 2000.
Alfred Kwesi Manyeh, Tobias Chirwa, Rohit Ramaswamy, Frank Baiden, Latifat Ibisomi   +4 more
doaj   +1 more source

Safety and immunogenicity of an adjuvanted human onchocerciasis vaccine candidate, OvMANE1: preclinical evaluation in a mice model

Clinical &Translational Immunology, Volume 15, Issue 7, 2026.
OvMANE1 formulated with Freund's adjuvant was safe and elicited strong humoral and cellular immune responses, including significant IgG and leukocyte activation. These findings highlight OvMANE1 as a promising multi‐epitope vaccine candidate for advancing onchocerciasis prevention.
Derrick Neba Nebangwa, Mary Teke Efeti, Sonia M. E. Momnougui, Cabirou Mounchili Shintouo, Robert Adamu Shey, Rene Bilingwe Ayiseh, Fidele Ntie‐Kang, Stephen Mbigha Ghogomu   +7 more
wiley   +1 more source