Results 101 to 110 of about 14,696 (273)

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

Advanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu, Wanpeng Zou, Yuekai Li, Jiayi Wang, Mingxuan Cai, Hongmin Cai   +5 more
wiley   +1 more source

Giant and extensive localized xanthoma associated with primary lymphedema

Indian Journal of Dermatology, 2019
Lymphedema is extravasation of lymphatic fluid into extracellular spaces and may be primary or secondary. Primary lymphedema may be caused by truncular lymphatic malformation.
Reena Kumari Sharma, Mudita Gupta
doaj   +1 more source

A Dynamic 3D Human Liver Sinusoid Model for Mechanistic Interrogation of Fontan‐Associated Liver Disease

Advanced Science, EarlyView.
This study presents a perfusable 3D bioengineered liver sinusoid platform that integrates biofabrication, 3D cell culture, controlled hemodynamics, and multiparametric characterization to model Fontan‐associated liver disease. By decoupling pressure and hypoxia effects, the system reveals early mechanobiological and profibrotic responses under ...
Sarah Rezapourdamanab, Mehdi Salar Amoli, Tanmay Mukherjee, Maryam Bagheri, Boeun Hwang, Linqi Jin, Yamini Singh, Sophia Norton, Ashay Vishwas Bongirwar, Shweta Karnik, Lakshmi Prasad Dasi, Reza Avazmohammadi, Rene Romero, Holly D. Bauser‐Heaton, Vahid Serpooshan   +14 more
wiley   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

The behavioral parenting interventions (BPT) for support and mandatory integrative therapy for children and adolescents affected by disruptive behavioural disorders: A brief review [PDF]

, 2017
The behavioral parenting interventions (BPT), commonly abbreviated as parent training, is a program conducted by an expert with the specific purpose of improving or modifying parental practices in order to promote the child's well-being, increasing ...
Barbanera F., Di Folco A., Gallai B., Lavano F., Lavano S. M., Maltese A., Marotta R., Romano P., Salerno M., Tripi G., Valentini V.   +10 more
core   +1 more source

Dumbbell‐Structured Plasmonic‐Enhanced Optical Nanoprobes Boosting Photo‐Magnetic‐Acoustic Multimodal Imaging‐Guided Photodynamic‐Photothermal Synergistic Treatment and Immunogenic Death in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study reports a novel rationally‐designed optical nanoprobe based on dumbbell‐shaped mesoporous silica‐coated gold nanorods, loaded with rare‐earth oxides, photosensitizers, and tumor‐targeted peptides, enabling plasmonic‐enhanced multimodal imaging and PTT‐PDT synergy.
Baikang Zhuang, Yubiao Yang, Wen Han, Yi Tang, Chengxin Yao, Fuli Zhao, Wenxiao Fang, Jinjie Li, Xiaolan Huo, Yiqian An, Yuanzhi Shao, Botao Gao, Jinchang Yin   +12 more
wiley   +1 more source

Aggressive giant cystic lymphatic malformation in a newborn

The Turkish Journal of Pediatrics, 2013
Lymphatic malformations are uncommon, benign and congenital malformations of the lymphatic system exhibiting lack of development of communication between the lymphatic and venous circulation.
Mert Calış, Ersoy Konaş, Şahin Takcı, Murat Yurdakök, Gökhan Tunçbilek   +4 more
doaj  

A Rare Case of Penile Lymphangioma Circumscriptum Treated with the Split-Thickness Skin Grafting Technique

Journal of Urological Surgery, 2015
Lymphangioma circumscriptum (LC) is an uncommon type of microcystic lymphatic malformation involving the skin and mucosa caused by saccular dilatation of lymphatic channels.
Nurullah Hamidi, Onur Telli, Berk Burgu
doaj   +1 more source

Quantitative Histomorphometry of the Healthy Peritoneum [PDF]

, 2016
The peritoneum plays an essential role in preventing abdominal frictions and adhesions and can be utilized as a dialysis membrane. Its physiological ultrastructure, however, has not yet been studied systematically.
Bartosova, Maria, Burkhardt, Dorothea, Holland-Cunz, Stefan, Lahrmann, Bernd, Macher-Goeppinger, Stephan, Nyarangi-Dix, Joanne, Pfeifle, Viktoria, Querfeld, Uwe, Sallay, Peter, Schaefer, Betti, Schaefer, Franz, Schmitt, Claus P., Schwenger, Vedat, Ujszaszi, Akos, Wallwiener, Markus, Wuehl, Elke   +15 more
core   +1 more source

Quantum Dots for Biomedical Biosensing, NIR‐II Bioimaging, and Phototherapy: Materials Design, Signal Transduction, and Translational Barriers

Advanced Science, EarlyView.
This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju, Zhifang Liu, Xinran Gao, Wen Sun, Wei Fu, Yanfei Wang   +5 more
wiley   +1 more source