Results 81 to 90 of about 14,696 (273)

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

open access: yesAdvanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao   +11 more
wiley   +1 more source

Novel application assigned to toluquinol: inhibition of lymphangiogenesis by interfering with VEGF-C/VEGFR-3 signalling pathway [PDF]

open access: yes, 2016
BACKGROUND AND PURPOSE Lymphangiogenesis is an important biological process associated with the pathogenesis of several diseases, including metastatic dissemination, graft rejection, lymphoedema and other inflammatory disorders.
Blacher, S.   +5 more
core  

Single‐Cell Metabolic Imaging and Digital Scoring of Fat Tissue Remodeling by Label‐Free Metabolic Microscopy

open access: yesAdvanced Science, EarlyView.
Mid‐infrared optoacoustic microscopy (MiROM) acquires lipid‐ and protein‐ associated vibrational contrast in intact fat tissue without dyes, preserving native tissue architecture. Through lateral and axial segmentation, MiROM tracks intrinsic intracellular changes during postnatal remodeling. A quantitative spatial analysis tool (Q‐SAT) maps white‐ and
Myeongseop Kim   +7 more
wiley   +1 more source

Clinical periodontal diagnosis

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi   +5 more
wiley   +1 more source

Complex giant arteriovenous and lymphatic malformation of the abdominal wall

open access: yesJournal of Pediatric Surgery Case Reports, 2020
Introduction: Vascular malformations can be congenital or traumatic, the former being the most common and resulting from the unregulated vascular development during the embryogenic period.
Oona Tomiê Daronch   +8 more
doaj   +1 more source

DOT1L Drives Endothelial‐to‐Mesenchymal Transition and Fibrotic Vascular Remodeling via H3K79 Methylation

open access: yesAdvanced Science, EarlyView.
DOT1L as a central epigenetic regulator of EndoMT and pulmonary fibrosis. Acting as an early epigenetic switch, it translates TGFβ–SMAD signaling into H3K79me2‐mediated chromatin remodeling, selectively activates fibrosis‐related genes, and primes ECs for rapid mesenchymal transition.
Yaofeng Wang   +11 more
wiley   +1 more source

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

Meeting Report for the 2023 International Scientific Conference on Complex Lymphatic Anomalies

open access: yesJournal of Vascular Anomalies
Objectives:. Complex lymphatic anomalies (CLAs) are rare diseases with variable clinical manifestations caused by the abnormal development of lymphatic vessels.
Michael T. Dellinger   +5 more
doaj   +1 more source

Retroperitoneal lymphatic malformation in a dog

open access: yesActa Veterinaria Scandinavica, 2020
Background Lymphatic vascular malformations are rare findings in canine patients with six reports available in veterinary literature. Retroperitoneal cystic lymphatic malformations have not been described previously in canine patients and neither has the
Floor Driessen   +2 more
doaj   +1 more source

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