Cellular signalling and growth control in vascular development and lymphatic malformations
Dr Kazuhide Shaun Okuda2023-12-15T00:00:00UniversityExcessive lymphatic vessel growth leads to childhood lymphatic malformations, resulting in severe pain and deformities.
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Abstract figure legend Paracetamol (acetaminophen) is commonly taken during pregnancy for pain and fever. To gain a more comprehensive understanding of paracetamol's effects during pregnancy, several elements need to be examined including the transfer of paracetamol across the placenta and into the developing brain, the short‐ and long‐term effects of ...
Yifan Huang, Liam Koehn
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Bioresorbable Scaffolds for Coronary Arteries: Where Do We Stand Today?
Bioresorbable coronary scaffolds are moving from thick strut pitfalls to thinner, stronger, healing‐oriented designs. Integrating advances in materials, guided implantation with preparation, size, and postdilation steps, and resorption aligned to healing, we synthesize clinical evidence and chart a roadmap toward intelligent, transient platforms ...
Junya Matsuda +5 more
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Multidimensional single-cell analysis reveals immune dysfunction and inflammatory response in lymphatic malformations. [PDF]
Chen C +12 more
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ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
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Medical Therapies for Pediatric Lymphatic Malformations: A Systematic Review. [PDF]
Hollman D +4 more
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Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle +5 more
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Surgical Management of Pediatric Lymphatic Malformations: A Cross-Sectional Study of Outcomes, Complications, and Recurrence at a Tertiary Care Center. [PDF]
Nwaijie NMA +4 more
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ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel +3 more
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Laparoscopic polidocanol foam sclerotherapy for retroperitoneal lymphatic malformations in children: a single center retrospective study. [PDF]
Lin S, Lin Y, Zhang B, Fang Y, Bai J.
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