Results 121 to 130 of about 732,589 (264)

Tumor-derived lymphangiogenic factors and lymphatic metastasis

Biomedicine & Pharmacotherapy, 2007
Lymphatic endothelial cells (LECs) originally differentiated from venous endothelial cells express several specific makers that distinguish them from the blood vessels. Lymphangiogenesis, a complex process of sprouting of new lymphatic vessels, is regulated by multiple direct and indirect growth factors. Vascular endothelial growth factor-C (VEGF-C) is
Yihai, Cao, Weide, Zhong
openaire   +2 more sources

Analysis of risk factors for lymphatic metastasis in patients diagnosed with early gastric cancer [PDF]

, 2022
Oscar Paredes, Carlos Baca, Carlos Luque-Vásquez, Iván Chavéz, Eloy Ruíz, Francisco Berrospi, Eduardo Payet   +6 more
openalex   +1 more source

Generation of sphingosine-1-phosphate is enhanced in biliary tract cancer patients and is associated with lymphatic metastasis

Scientific Reports, 2018
Lymphatic metastasis is known to contribute to worse prognosis of biliary tract cancer (BTC). Recently, sphingosine-1-phosphate (S1P), a bioactive lipid mediator generated by sphingosine kinase 1 (SPHK1), has been shown to play an important role in ...
Yuki Hirose, Masayuki Nagahashi, Eriko Katsuta, Kizuki Yuza, Kohei Miura, Jun Sakata, Takashi Kobayashi, Hiroshi Ichikawa, Yoshifumi Shimada, Hitoshi Kameyama, Kerry-Ann McDonald, Kazuaki Takabe, Toshifumi Wakai   +12 more
doaj   +1 more source

The role of VEGF-C/D and Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma

Journal of Experimental & Clinical Cancer Research, 2009
Background To investigate the role of vascular endothelial growth factors (VEGF)-C/D and their receptor Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma.
Zhang Renhua, Zhang Shiqian, Yu Hao, Zhang Linlin   +3 more
doaj   +1 more source

Optimization and regeneration kinetics of lymphatic-specific photodynamic therapy in the mouse dermis. [PDF]

, 2013
Lymphatic vessels transport fluid, antigens, and immune cells to the lymph nodes to orchestrate adaptive immunity and maintain peripheral tolerance. Lymphangiogenesis has been associated with inflammation, cancer metastasis, autoimmunity, tolerance and ...
Golab, J., Kilarski, W.W., Muchowicz, A., Mężyk-Kopeć, R., Nowak-Sliwinska, P., Swartz, M.A., Wachowska, M.   +6 more
core   +1 more source

Sentinel Node and Mechanism of Lymphatic Metastasis

Annals of Vascular Diseases, 2012
The validity and clinical usefulness of the sentinel node (SN) concept for breast cancer has been confirmed, and individualized limited surgery based on diagnosis of SN metastasis is presently performed. In the future, SN navigation surgery (SNNS) will be actively applied to the treatment of early gastric cancer, and an intraoperative real-time reverse
Hiroya, Takeuchi, Yuko, Kitagawa
openaire   +3 more sources

From Mechanisms to Treatment: A Comprehensive View of Lymphatic Metastasis in Cancer

Lymphatics
The lymphatic system, a complex and dynamic network comprising lymphatic vessels, lymph nodes (LNs), and associated lymphoid tissues, plays a pivotal role in regulating interstitial fluid balance and providing immune surveillance across the body.
Nitya Devisetti, Pushti Shah, Farrah C. Liu   +2 more
doaj   +1 more source

An HGF‐dependent positive feedback loop between bladder cancer cells and fibroblasts mediates lymphangiogenesis and lymphatic metastasis [PDF]

, 2023
Yuting Li, Hanhao Zheng, Yuming Luo, Yan Lin, Mingjie An, Yao Kong, Yue Zhao, Yina Yin, Le Ai, Jian Huang, Changhao Chen   +10 more
openalex   +1 more source

Angiopoietin‐2 drives lymphatic metastasis of pancreatic cancer

The FASEB Journal, 2011
ABSTRACT Lymphatic metastasis constitutes a critical route of disease dissemination, which limits the prognosis of patients with pancreatic ductal adenocarcinoma (PDAC). As lymphangiogenesis has been implicated in stimulation of lymphatic metastasis by vascular endothelial growth factor‐C (VEGF‐C) and VEGF‐D, we ...
Schulz, Petra, Fischer, Christian, Detjen, Katharina M., Rieke, Svenja, Hilfenhaus, Georg, von Marschall, Zofia, Boehmig, Michael, Koch, Inga, Kehrberger, Jenny, Hauff, Peter, Thierauch, Karl Heinz, Alves, Frauke, Wiedenmann, Bertram, Scholz, Arne   +13 more
openaire   +3 more sources

Spatio-temporal Models of Lymphangiogenesis in Wound Healing

, 2016
Several studies suggest that one possible cause of impaired wound healing is failed or insufficient lymphangiogenesis, that is the formation of new lymphatic capillaries.
A Bianchi, A Castiglioni, A Christiansen, A Friedman, A Gosiewska, A Louveau, A Mantovani, A Saaristo, A Stéphanou, AB Sutton, AI Papaioannou, AJ Macdonald, AJ Singer, Arianna Bianchi, AV Benest, AW Taylor, AY Sheikh, B Greenwood, B Kaminska, B Whitehurst, BE Farrell, BM Berg van den, C Cao, C Heppell, C Norrmen, CA Cobbold, CH Cho, CL Helm, CT Ambrose, D Ludwig, DJ Grainger, DR Brown, E Hormbrey, E Mendoza, EK Rofstad, ETT Withington, F Krombach, F Mac Gabhann, G Crescenzo De, G Müller, G Oliver, GF Pierce, GJ Goodhill, H Brem, H Kaur, H Staden von, HA Levine, HM Byrne, HM Byrne, HV Waugh, I Barkefors, I Choi, I Nunes, I Zachary, J Asai, J Goldman, J Posnett, JA Flegg, JC Zhuang, JD Shields, JF Douglas, JJL Velázquez, JJL Velázquez, JM Rutkowski, JM Rutkowski, Jonathan A. Sherratt, JP Yang, K Maruyama, K Weber-Matthiesen, KC Boardman, KE Murphy, Kevin J. Painter, KN Margaris, L Edelstein, L Yang, LM Wakefield, M Fischer, M Hyytiäinen, M Lohela, M Oi, M Scianna, M Shi, MAJ Chaplain, ME Fleury, ME Swift, MH Witte, MTGT May, N Khalil, N Khalil, N Li Jeon, NP Reddy, NV Mantzaris, P Drew, P Galie, PN Bernatchez, R Boulton, R Huggenberger, RC Ji, RC Schugart, RH Adams, RS Sweat, RT Tranquillo, S Kiriakidis, S Lee, S Monstrey, S Podgrabinska, S Zimny, SJ Lunt, SM Wahl, T Miura, T Roose, T Tammela, TG Simonsen, TL Haas, VPKH Nguyen, WJ Jeffcoate, Y Cao, Y Zheng   +117 more
core   +1 more source