Results 261 to 270 of about 696,685 (294)

Aminopeptidase N Activatable Nanoprobe for Tracking Lymphatic Metastasis and Guiding Tumor Resection Surgery via Optoacoustic/NIR-II Fluorescence Dual-Mode Imaging.

Analytical Chemistry, 2022
Lymphatic metastasis is a crucial mechanism by which the cancer cells break away from the primary (original) tumor and travel to the closest regional lymph node(s) and ultimately to other organs or parts of the body, which is closely associated with ...
Junjie Chen, Longqi Chen, Fang Zeng, Shuizhu Wu   +3 more
semanticscholar   +1 more source

Lymphatic invasion and metastasis

Experientia, 1977
The phenomenon of experimental lymphatic invasion and metastasis has been reviewed. The invasion of lymphatics must be dependent on the same factors as are involved in neoplastic invasion in generalcell motility, lack of adhesiveness, release of lytic enzymes, increase in cell population and tissue pressure and active migration of cells. The process of
I. Carr, C. van de Velde
openaire   +3 more sources

Lymphatic metastasis with childhood rhabdomyosarcoma

Cancer, 1977
Clinico-pathologic reviews of series of children with rhabdomyosarcoma have yielded conflicting information regarding frequency of lymphatic spread of this disease. The 264 eligible entries in the Intergroup Rhabdomyosarcoma Study (from November 1972 to September 1975) have been categorized by a prospective staging system and pre-treatment ...
Walter Lawrence, Daniel M. Hays, Thomas E. Moon   +2 more
openaire   +5 more sources

Lymphatic Metastasis in the Absence of Functional Intratumor Lymphatics

Science, 2002
Lymphatic metastasis contributes to mortality from solid tumors. Whether metastasizing cancer cells reach lymph nodes via intratumor lymphatic vessels is unknown. Here, we examine functional lymphatics associated with mouse tumors expressing normal or elevated levels of vascular endothelial growth factor–C (VEGF-C), a molecule that stimulates ...
Yves Boucher, Emmanuelle di Tomaso, Carla Mouta Carreira, Edward B. Brown, Ananth Kadambi, Rakesh K. Jain, John C. Wain, Lance L. Munn, Douglas J. Mathisen, Noah C. Choi, Timothy P. Padera, Eugene J. Mark   +11 more
openaire   +3 more sources

Lymphatic metastasis and its treatment

Cancer Treatment Reviews, 1987
The treatment of lymphatic metastasis depends on an understanding of its basic biology. We are still uncertain as to how human cancer cells enter lymphatic vessels and as to what reactions if any in the draining lymph node inhibit metastasis. We are uncertain as to whether lymphatic metastasis is an indicator or a governor of rapid dissemination, and ...
Brian H. Weinerman, Brian H. Weinerman, Norman M. Pettigrew, I. Carr, I. Carr   +4 more
openaire   +2 more sources

Targeting Lymphatic Metastasis

Science, 2002
Oncologists have long debated the part played by the lymphatic system of cancer patients in tumor metastasis. In a Perspective, Gershenwald and Fidler discuss new findings ( Padera et al .) showing that the lymphatic vessels surrounding tumors contribute to lymphatic metastasis.
Jeffrey E. Gershenwald, Isaiah J. Fidler
openaire   +2 more sources

Molecular Control of Lymphatic Metastasis

Annals of the New York Academy of Sciences, 2008
The metastatic spread of tumor cells is the most lethal aspect of cancer and often occurs via the lymphatic vasculature. Both experimental tumor models and human clinicopathologic data indicate that growth of lymphatic vessels (lymphangiogenesis) near solid tumors is often associated with lymph node metastasis.
Marc G. Achen, Steven A. Stacker
openaire   +3 more sources

ANXA3-rich exosomes derived from tumor-associated macrophages regulate ferroptosis and lymphatic metastasis of laryngeal squamous cell carcinoma.

Cancer immunology research
Tumor-associated macrophages (TAMs) induce immunosuppression in laryngeal squamous cell carcinoma (LSCC). The interaction between LSCC cells and TAMs affects the progression of laryngeal cancer through exosomes, but the underlying molecular mechanism ...
Licheng Xu, Wenjing Li, Danxi Liu, Jing Cao, J. Ge, Xinyu Liu, Yue Wang, Yujian Teng, Pengyan Liu, Xinyue Guo, Chen He, Ming Liu, L. Tian   +12 more
semanticscholar   +1 more source

Lymphatic metastasis

CANCER AND METASTASIS REVIEW, 1983
Lymphatic metastasis is an important mechanism in the spread of human cancer. During its course, tumor cells first penetrate the basement of membrane of the epithelium, in which they arise, and then the underlying connective tissue, carried partly by hydrostatic pressure.
openaire   +2 more sources

Experimental lymphatic metastasis

Journal of Microscopy, 1983
SUMMARYA model of lymphatic metastasis of cancer has been established by injecting tumour cells into the rat footpad and examining the draining popliteal lymph node. The node can probably destroy only a few tumour cells; thereafter metastasis is progressive and lethal.
openaire   +3 more sources