Results 261 to 270 of about 136,324 (301)

Lymphatic metastasis

CANCER AND METASTASIS REVIEW, 1983
Lymphatic metastasis is an important mechanism in the spread of human cancer. During its course, tumor cells first penetrate the basement of membrane of the epithelium, in which they arise, and then the underlying connective tissue, carried partly by hydrostatic pressure.
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Experimental lymphatic metastasis

Journal of Microscopy, 1983
SUMMARYA model of lymphatic metastasis of cancer has been established by injecting tumour cells into the rat footpad and examining the draining popliteal lymph node. The node can probably destroy only a few tumour cells; thereafter metastasis is progressive and lethal.
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Gastrointestinal cancer metastasis and lymphatic advancement

Surgery Today, 2010
The role of angiogenesis in the growth of solid tumors is well established, but the role of lymphatic vessels and the relationship between lymphangiogenesis and tumor spread are less clear. Recently, the molecular pathway that signals lymphangiogenesis and specific markers for lymphatic endothelium have been discovered; however, the lymphatic pathway ...
Kazuhide, Kumagai, Kouji, Shimizu, Noboru, Yokoyama, Sadatsugu, Aida, Takayuki, Tanaka, Kennichi, Yamagata   +5 more
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Adhesion mechanisms in lymphatic metastasis

Cancer and Metastasis Review, 1991
The role of cellular adhesion in regional lymph node metastasis of solid tumors has been investigated. The data reviewed is based on studies in four different tumor models of human, rat and murine origin. An in vitro assay measuring tumor cell attachment to cryostat sections of normal peripheral lymph nodes, obtained from the species of tumor origin ...
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Lymphatic function, lymphangiogenesis, and cancer metastasis

Microscopy Research and Technique, 2001
AbstractThe lymphatic system serves as the primary route for the metastasis of many cancers and the extent of lymph node involvement is the most important indicator of tumor aggressiveness. Despite the apparent importance of the lymphatic vessels for tumor dissemination, it has remained unclear whether activation of lymphatic endothelial cells may ...
M A, Swartz, M, Skobe
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Lymphatic Metastasis of Neoplasms

1983
Human cancers commonly metastasize by the lymphatics to draining lymph nodes. The existence of lymphatic vessels has been known since the observations of Aselli in 1622 and the fact that cancer can spread to lymph nodes was “well-known”to Pearson in 1793 (reviewed by Mayerson, 1969; Onuigbo, 1972).
Ian Carr, Jean Carr
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Targeted Treatment for Lymphedema and Lymphatic Metastasis

Annals of the New York Academy of Sciences, 2008
The presence of lymphatic vessels has been known for centuries, but the key players regulating the lymphatic vessel growth and function have only been discovered during the recent decade. The lymphatic vasculature is essential for maintenance of normal fluid balance and for the immune response.
Tomi, Tervala, Erkki, Suominen, Anne, Saaristo   +2 more
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Molecular mechanisms and imaging of lymphatic metastasis

Experimental Cell Research, 2013
In many types of cancer, tumors metastasize through the lymphatic system to draining lymph nodes. These sentinel lymph nodes have gained increased attention as a prognostic indicator for the severity of the disease, leading to the sentinel lymph node mapping and biopsy procedure to be accepted as standard-of-care for breast cancer and melanoma. However,
Proulx ST, Detmar M
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Experimental models of lymphatic metastasis

1982
The common human cancers spread by lymphatic metastasis [1], but most experimental work on metastasis has been done with models of hematogenous metastasis since this occurs much more readily in animal systems. The classic work on lymphatic metastasis was that of Zeidman and Buss [2], but until 1970 the field was relatively unexplored.
I. Carr, J. Carr
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Cancer stem cells, lymphangiogenesis, and lymphatic metastasis

Cancer Letters, 2015
Although current opinion indicates that tumor-induced lymphangiogenesis plays a key role in promoting the initial spread of malignant tumors, the mechanism that underlies lymphatic spread is not clear. The recent discovery of cancer stem cells (CSCs) in human tumors has challenged our current understanding of tumor recurrence, drug resistance, and ...
Shuang, Li, Qin, Li
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