Results 211 to 220 of about 22,605,370 (372)

Possibilities of Inner Ear Barrier Models for Otologic Drug Development

open access: yesAdvanced Therapeutics, EarlyView.
This review examines innovative organ chip models that reconstruct critical inner ear barriers, addressing a fundamental challenge in otologic drug development: the limited understanding of pharmaceutical behavior across these complex barriers. By replicating these barriers, the advanced models offer promising alternatives to traditional testing ...
Yeji Ahn   +7 more
wiley   +1 more source

Trimethylamine-N-oxide damages astrocytes and lymphatic endothelial cells in the cerebral lymphatic system. [PDF]

open access: yesIBRO Neurosci Rep
Su ML   +8 more
europepmc   +1 more source

A Systematic Approach to Analyze T Cell Migration: Application to Mouse Melanoma Tumors

open access: yesAdvanced Therapeutics, EarlyView.
The results show that a minimum of two migration speeds can be rigorously identified from the data with cells switching between a fast, persistent migratory state, and a slow, random migration state. These results will help in identifying genetic factors that influence rapid migration, among other applications, such as quality control for CAR‐T cell ...
Nikolaos Memmos   +4 more
wiley   +1 more source

The Cerebral Lymphatic System: Function, Controversies, and Therapeutic Approaches for Central Nervous System Diseases. [PDF]

open access: yesCell Mol Neurobiol
Pan J   +10 more
europepmc   +1 more source

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