A spatially-organized multicellular innate immune response in lymph nodes limits systemic pathogen spread [PDF]
, 2012 The lymphatic network that transports interstitial fluid and antigens to lymph nodes constitutes a conduit system that can be hijacked by invading pathogens to achieve systemic spread unless dissemination is blocked in the lymph node itself.
Germain, R. +4 more
core +1 more source
Morphofunctional Alteration of Mesenteric Lymph Nodes in the Inflammation of the Abdominal Cavity
BiologyThis paper provides data regarding the ratios of the functional structures of lymph nodes after inflammation in the abdominal organs. Lymph systems, including lymph nodes, function as filters of tissues and tissue fluids and are places of origin and ...
Serik N. Abdreshov +6 more
doaj +1 more source
Content-specific auditing of a large scale anatomy ontology [PDF]
, 2009 Biomedical ontologies are envisioned to be usable in a range of research and clinical applications. The requirements for such uses include formal consistency, adequacy of coverage, and possibly other domain specific constraints.
Brinkley, James F +4 more
core +1 more source
Frontiers in Physiology, 2023 Enhancing our understanding of lymphatic anatomy from the microscopic to the anatomical scale is essential to discern how the structure and function of the lymphatic system interacts with different tissues and organs within the body and contributes to ...
Dhruv Singhal +16 more
doaj +1 more source
Vascular endothelial growth factor receptor-2 promotes the development of the lymphatic vasculature. [PDF]
PLoS ONE, 2013 Vascular endothelial growth factor receptor 2 (VEGFR2) is highly expressed by lymphatic endothelial cells and has been shown to stimulate lymphangiogenesis in adult mice. However, the role VEGFR2 serves in the development of the lymphatic vascular system
Michael T Dellinger +4 more
doaj +1 more source
Meningeal Lymphatics: An Immune Gateway for the Central Nervous System
Cells, 2021 The recent (re)discovery of the meningeal lymphatic system has opened new theories as to how immune cells traffic and interact with the central nervous system (CNS).
Gabriel A. Tavares, Antoine Louveau
doaj +1 more source
The dual role of tumor lymphatic vessels in dissemination of metastases and immune response development [PDF]
, 2016 Lymphatic vasculature plays a crucial role in the immune response, enabling transport of dendritic cells (DCs) and antigens (Ags) into the lymph nodes. Unfortunately, the lymphatic system has also a negative role in the progression of cancer diseases, by
Golab, Jakub +5 more
core +1 more source
A new lymphography protocol and interpretation principles based on functional lymphatic anatomy in lower limb lymphedema [PDF]
, 2023 Indirect lymphatic system imaging is essential for diagnosing lymphatic diseases. The basic methodology involves intradermal or subcutaneous injection of a contrast agent into the surrounding lymphatic capillary, and the flow of the contrast agent is ...
Shinaoka, Akira
core +1 more source
Structure-preserving semi-convex-splitting numerical scheme for a Cahn-Hilliard cross-diffusion system in lymphangiogenesis [PDF]
arXiv, 2023 A fully discrete semi-convex-splitting finite-element scheme with stabilization for a Cahn-Hilliard cross-diffusion system is analyzed. The system consists of parabolic fourth-order equations for the volume fraction of the fiber phase and solute concentration, modeling pre-patterning of lymphatic vessel morphology.
arxiv