Results 51 to 60 of about 18,325,039 (298)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

The lymphatic vascular system in liver diseases: its role in ascites formation [PDF]

Clinical and Molecular Hepatology, 2013
The lymphatic system is part of the circulatory system and plays a key role in normal vascular function. Its failure plays a crucial role in the development and maintenance of various diseases including liver diseases.
Chuhan Chung, Yasuko Iwakiri
doaj   +1 more source

Review on the Lymphatic Vessels in the Dental Pulp

Biology, 2021
Despite many studies, opinions on the lymphatic system of the teeth are still incompatible. Studies using light and electron microscopy and directly using methods such as a radioisotope (radionuclide) scan and interstitial fluid pressure measurement ...
Kamila Wiśniewska, Zbigniew Rybak, Maria Szymonowicz, Piotr Kuropka, Maciej Dobrzyński   +4 more
doaj   +1 more source

Developing eradication investment cases for onchocerciasis, lymphatic filariasis, and human African trypanosomiasis : rationale and main challenges [PDF]

, 2013
An EIC is essentially an economic composite assessment in the broader meaning of economics, addressing thus all three fundamental economics questions. An EIC in fact answers: 1) the ‘‘What’’ question, that compares remaining in control mode versus moving
Steinmann, Peter, Marcel Tanner, Peter Steinmann, de Savigny, Don, Tediosi, Fabrizio, Fabrizio Tediosi, Don de Savigny, María Gloria Basáñez, Tanner, Marcel, Tediosi F, de Savigny D, Steinmann P, Tanner M   +12 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Mapping the lymphatic system across body scales and expertise domains: A report from the 2021 National Heart, Lung, and Blood Institute workshop at the Boston Lymphatic Symposium

Frontiers in Physiology, 2023
Enhancing our understanding of lymphatic anatomy from the microscopic to the anatomical scale is essential to discern how the structure and function of the lymphatic system interacts with different tissues and organs within the body and contributes to ...
Dhruv Singhal, Katy Börner, Elliot L. Chaikof, Michael Detmar, Maija Hollmén, Jeffrey J. Iliff, Maxim Itkin, Taija Makinen, Guillermo Oliver, Timothy P. Padera, Ellen M. Quardokus, Andrea J. Radtke, Hiroo Suami, Griffin M. Weber, Ilsa I. Rovira, Selen C. Muratoglu, Zorina S. Galis   +16 more
doaj   +1 more source

Regulation of Lymphatic Vasculature by Extracellular Matrix

, 2013
The extracellular matrix (ECM) is a complex but highly organized network of macromolecules with different physical, biochemical, and mechanical properties.
Lutter, Sophie, Mäkinen, Taija,, Taija Makinen, Sophie Lutter   +3 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Meningeal Lymphatics: An Immune Gateway for the Central Nervous System

Cells, 2021
The recent (re)discovery of the meningeal lymphatic system has opened new theories as to how immune cells traffic and interact with the central nervous system (CNS).
Gabriel A. Tavares, Antoine Louveau
doaj   +1 more source

Compartmentalized ocular lymphatic system mediates eye-brain immunity. [PDF]

Nature
Yin X, Zhang S, Lee JH, Dong H, Mourgkos G, Terwilliger G, Kraus A, Geraldo LH, Poulet M, Fischer S, Zhou T, Mohammed FS, Zhou J, Wang Y, Malloy S, Rohner N, Sharma L, Salinas I, Eichmann A, Thomas JL, Saltzman WM, Huttner A, Zeiss C, Ring A, Iwasaki A, Song E.   +25 more
europepmc   +2 more sources