Results 81 to 90 of about 22,262,144 (390)
Engineering the Lymphatic System [PDF]
The recent advances in our understanding of lymphatic physiology and the role of the lymphatics in actively regulating fluid balance, lipid transport, and immune cell trafficking has been furthered in part through innovations in imaging, tissue engineering, quantitative biology, biomechanics, and computational modeling.
Matthew E. Nipper, J. Brandon Dixon
openaire +3 more sources
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Glymphatic System as a Gateway to Connect Neurodegeneration From Periphery to CNS
The classic concept of the absence of lymphatic vessels in the central nervous system (CNS), suggesting the immune privilege of the brain in spite of its high metabolic rate, was predominant until recent times.
Gianfranco Natale+7 more
doaj +1 more source
The cardiac lymphatic system stimulates resolution of inflammation following myocardial infarction
Myocardial infarction (MI) arising from obstruction of the coronary circulation engenders massive cardiomyocyte loss and replacement by non-contractile scar tissue, leading to pathological remodeling, dysfunction, and ultimately heart failure.
J. Vieira+10 more
semanticscholar +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
The human body has two main circulatory systems, the blood and lymphatic systems. Although both systems share many functional, structural and anatomical similarities, the two vascular systems have many differences in science and medicine.
Oktay Cakmakcı, Ali Tatlıcı
doaj
Lymphangiogenesis and angiogenesis during human fetal pancreas development [PDF]
Background: The complex endocrine and exocrine functionality of the human pancreas depends on an efficient fluid transport through the blood and the lymphatic vascular systems. The lymphatic vasculature has key roles in the physiology of the pancreas and
Carlotti, Françoise+6 more
core +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Investigating the Effects of Shear Stress on the Protein Expression of Lymphatic Endothelial Cells (LECs) [PDF]
The lymphatic system plays three main important roles: Its cells are primarily responsible for the immune response of the human body, it represents a separate circulatory system, and it is involved in the transport of select nutrients from the digestive ...
Hussein, Tawfik M
core +1 more source
[Lymphatic system in central nervous system].
The considerable metabolic activity of the central nervous system (CNS) requires an efficient system of tissue drainage and detoxification. The CNS is however devoid of lymphatic vessels, a vasculature ensuring interstitial fluid drainage and immune ...
Jean-Léon Thomas+2 more
semanticscholar +1 more source