Results 81 to 90 of about 22,605,370 (372)

Engineering the Lymphatic System [PDF]

open access: yesCardiovascular Engineering and Technology, 2011
The recent advances in our understanding of lymphatic physiology and the role of the lymphatics in actively regulating fluid balance, lipid transport, and immune cell trafficking has been furthered in part through innovations in imaging, tissue engineering, quantitative biology, biomechanics, and computational modeling.
Matthew E. Nipper, J. Brandon Dixon
openaire   +3 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Exercise and Lymphatic System

open access: yesTürk Spor ve Egzersiz Dergisi, 2021
The human body has two main circulatory systems, the blood and lymphatic systems. Although both systems share many functional, structural and anatomical similarities, the two vascular systems have many differences in science and medicine.
Oktay Cakmakcı, Ali Tatlıcı
doaj  

Development and Clinical Validation of the LymphMonitor Technology to Quantitatively Assess Lymphatic Function

open access: yesDiagnostics, 2021
Current diagnostic methods for evaluating the functionality of the lymphatic vascular system usually do not provide quantitative data and suffer from many limitations including high costs, complexity, and the need to perform them in hospital settings. In
Anna Polomska   +6 more
doaj   +1 more source

Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures [PDF]

open access: yes, 2013
Insertion of bone substitution materials accelerates healing of osteoporotic fractures. Biodegradable materials are preferred for application in osteoporotic patients to avoid a second surgery for implant replacement. Degraded implant fragments are often
Alt, Volker   +16 more
core   +2 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Evolution of Anatomical Studies on the Arterial, Venous, and Lymphatic System in Plastic Surgery

open access: yesArchives of Plastic Surgery, 2022
Anatomies of the vascular and lymphatic systems have been vital research topics in reconstructive surgery. Harvey was a pioneer who provided the earliest descriptions of the cutaneous vasculature in the 17th century.
Soo Jin Woo   +4 more
doaj   +1 more source

Lymphatic endothelium in health and disease [PDF]

open access: yes, 2018
The lymphatic vascular system has an important role in the maintenance of tissue fluid pressure homeostasis, in the mediation of the afferent immune response via recruitment of antigen-presenting cells toward draining lymph nodes, and in the intestinal ...
Detmar, Michael, Jurisic, Giorgia
core  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

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