Results 111 to 120 of about 1,026,018 (392)

Synchronization and Random Triggering of Lymphatic Vessel Contractions

PLoS Comput. Biol., 2016
The lymphatic system is responsible for transporting interstitial fluid back to the bloodstream, but unlike the cardiovascular system, lacks a centralized pump-the heart–to drive flow.
J. Baish, Christian Kunert, T. Padera, L. Munn   +3 more
semanticscholar   +1 more source

Lymphatic Vessels in Chronic Rhinosinusitis

Journal of Inflammation Research
The purpose of this study was to analyze the nasal lymphatic system in order to uncover novel factors that might be involved in pathogenesis of chronic rhinosinusitis (CRS) with (CRSwNP) and without nasal polyps (CRSsNP).Lymphatic vessels (LVs) and macrophages were localized and counted in the inferior and middle turbinate, the uncinate process and the
Vanessa-Vivien Pesold, Olaf Wendler, Franziska Gröhn, Sarina Mueller   +3 more
openaire   +4 more sources

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

GATA2 is required for lymphatic vessel valve development and maintenance.

Journal of Clinical Investigation, 2015
Heterozygous germline mutations in the zinc finger transcription factor GATA2 have recently been shown to underlie a range of clinical phenotypes, including Emberger syndrome, a disorder characterized by lymphedema and predisposition to myelodysplastic ...
J. Kazenwadel, Kelly L. Betterman, Chan-Eng Chong, P. H. Stokes, Young K. Lee, G. Secker, Yan Agalarov, Cansaran Saygili Demir, D. Lawrence, Drew L. Sutton, S. Tabruyn, N. Miura, M. Salminen, T. Petrova, J. Matthews, C. Hahn, H. Scott, N. Harvey   +17 more
semanticscholar   +1 more source

Sacrificial Biofabrication for Vascularization: Concept, Materials, Technologies, and Applications

Advanced Materials, EarlyView.
Vasculature is indispensable for tissue viability in regenerative medicine. The sacrificial biofabrication enables precise fabrication of vascular channels by using temporary templates that are subsequently removed. This review defines the concept and delves into sacrificial materials, surrounding materials, fabrication technologies, and biomedical ...
Jiezhong Shi, Chunyao Wang, Xuan Mei, Ben Zhang, Junxi Wu, Rylie A. Green, Yu Shrike Zhang, Wenmiao Shu   +7 more
wiley   +1 more source

VIPAR, a quantitative approach to 3D histopathology applied to lymphatic malformations. [PDF]

, 2017
BACKGROUND: Lack of investigatory and diagnostic tools has been a major contributing factor to the failure to mechanistically understand lymphedema and other lymphatic disorders in order to develop effective drug and surgical therapies.
Butz, S, Dierkes, C, Drees, D, Goerge, T, Gordon, K, Hinrichs, K, Hägerling, R, Jiang, X, Kiefer, F, Mansour, S, Martin-Almedina, S, Mortimer, PS, Ostergaard, P, Scherzinger, A, Schäfers, M, Vestweber, D   +15 more
core   +1 more source

Lymph flow regulates collecting lymphatic vessel maturation in vivo.

Journal of Clinical Investigation, 2015
Fluid shear forces have established roles in blood vascular development and function, but whether such forces similarly influence the low-flow lymphatic system is unknown.
D. T. Sweet, J. M. Jiménez, Jeremy Chang, P. Hess, Patricia Mericko-Ishizuka, Jianxin Fu, Lijun Xia, P. Davies, M. Kahn   +8 more
semanticscholar   +1 more source

Nanostructured Protein Surfaces Inspired by Spider Silk

Advanced Materials, EarlyView.
Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley   +1 more source

New Microcannulation Technique for Imaging Contrast and Drug Delivery via the Lymphatics

Plastic and Reconstructive Surgery, Global Open
Summary:. A technique for drug delivery using the lymphatics was introduced and tested in animals half a century ago, but was never trialed in human subjects. Recently, surgical manipulation of lymphatic vessels for lymphedema treatment has attracted the
Hiroo Suami, MD, PhD
doaj   +1 more source

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source