Results 91 to 100 of about 450,414 (301)

Lymphatic vessel density in radical prostatectomy specimens

, 2008
Formation of new lymphatic channels, or lymphangiogenesis, has been associated with poor prognosis in a number of human cancers. Its prognostic significance in prostate cancer is uncertain.
Cheng L., Maclennan G. T., Bishop E., Zhou H., Baldridge L. A., Zhang S., Lopez Beltran A., Badve S., MONTIRONI, RODOLFO   +8 more
core   +1 more source

Correlation of both morphometric quantification methods, lymphatic vessel density and Chalkley count.

, 2023
Mean values of lymphatic vessel density (LVD) and Chalkley Count (CC) of all cases analyzed are graphically illustrated and correlated using Spearman`s or Pearson’s correlation coefficient, displaying equivalence of both quantification methods.
Sabrina K. Müller (14498354), Roland Moll (567031), Paul Jank (9300030), Matthias Kalder (3533060), Christina C. Westhoff (14498351)   +4 more
core   +1 more source

Flexible Integration of Structurally Diverse Spatial Multi‐Omics With AgaeSMO

Advanced Science, EarlyView.
AgaeSMO is a versatile and robust deep learning framework for flexible cross‐integration of spatial multi‐omics data. Leveraging a GATs network with a graph attention module, it learns joint embedding across diverse modalities, enabling integration of both structurally paired (e.g., spatial transcriptome‐epigenome, transcriptome‐proteome, transcriptome‐
Kunpeng Liu, Jinpo Su, Haotian Zhou, Yilin Shen, Mengke Qin, Yingjie Luo, Tiancai Wang, Zhenglin Chen, Yuanyuan Wang, Xiaokai Ma   +9 more
wiley   +1 more source

Mechanical feedback mechanisms in a multiscale sliding filament model of lymphatic muscle pumping

Applications in Engineering Science
The lymphatic system maintains bodily fluid balance by returning interstitial fluid to the venous system. Flow can occur through a combination of extrinsic pumping, due to forces from surrounding tissues, and intrinsic pumping involving contractions of ...
Peter Y. Xie, Christopher J. Morris, Christopher D. Bertram, Michael J. Davis, Samira Jamalian, Mohammad Jafarnejad, David C. Zawieja, James E. Moore, Jr   +7 more
doaj   +1 more source

Heterogeneity in VEGFR3 levels drives lymphatic vessel hyperplasia through cell-autonomous and non-cell-autonomous mechanisms

Nature Communications, 2018
VEGF-C is a key regulator of lymphatic development. Here, Zhang et al. show that while complete loss of its receptor VEGFR3 results in vessel hypoplasia, mosaic loss of VEGFR3 leads to hyperplasia through induction of cell proliferation in neighboringnon-
Yan Zhang, Maria H. Ulvmar, Lukas Stanczuk, Ines Martinez-Corral, Maike Frye, Kari Alitalo, Taija Mäkinen   +6 more
doaj   +1 more source

Lymphatic Vessel Density Is Significantly Increased in Melanoma

, 2004
Backgrounds: Melanoma is well known for its ability to involve regional lymph nodes in the early stage. However, the presence of lymphangiogenesis in melanoma is still controversial due to lack of lymphatic-specific markers. The purpose of this study was
Acs, G., Giorgadze, T. A., Elder, D. E., Coogan, P. S., Xu, Xiaowei, Zhang, P. J., Pasha, T.   +6 more
core   +1 more source

Sustainable Hydrogel‐Forming Microneedle‐Reservoir Patches for Transdermal Delivery of Hydrophilic Macromolecules: Biopolymers, Green Manufacturing and Translation

Advanced Science, EarlyView.
Hydrogel‐forming microneedle (HFMN)‐reservoir patches provide a modular route for controlled transdermal delivery of hydrophilic biomacromolecules. The platform integrates skin‐barrier penetration, sustainable biopolymers, scalable green manufacturing, hydration‐driven transport, model‐cargo validation, and translational quality requirements.
Siddharth Mohanty, Mehmet Onur Aydogdu, Sijia Kang, Xinbo Li, Mohan Edirisinghe   +4 more
wiley   +1 more source

Randomized preclinical study of machine perfusion in vascularized composite allografts

BJS (British Journal of Surgery), EarlyView., 2020
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin, J. P. Stone, J. Kerr, A. Geraghty, L. Joseph, A. Montero‐Fernandez, J. K. Wong, J. E. Fildes   +7 more
wiley   +1 more source

Kynurenic acid mediates epicardial fat-induced lymphatic metabolic dysfunction in atrial fibrillation

Nature Communications
Atrial fibrillation represents a prevalent cardiac arrhythmia whose pathogenic mechanisms remain incompletely understood. Here, we identify impaired atrial lymphangiogenesis as a critical determinant in atrial fibrillation pathogenesis. Analysis of human
Masaki Takahashi, Ichitaro Abe, Naofumi Yoshida, Daisuke Katoh, Daishi Fujita, Shunsuke Goto, Hirochika Yamasaki, Toshiyuki Ko, Yue Jiang, Yu He, Shinji Ito, Taisuke Harada, Masayuki Takano, Hiroki Sato, Hidekazu Kondo, Akira Fukui, Yasushi Teshima, Hidenori Sako, Keisuke Ohta, Shinji Miyamoto, Toshimasa Yamauchi, Seitaro Nomura, Norihiko Takeda, Issei Komuro, Naohiko Takahashi   +24 more
doaj   +1 more source

Incidence of lymphatic vessel, vascular vessel or pleural invasion in small adenocarcinomas according to tumour dimension using mediastinal window (MD) settings.

, 2014
A black bar showed a patient with invasion to any of lymphatic vessel, vascular vessel or pleura, and a gray bar showed a patient without any of them.
Yuichi Ishikawa (653718), Yukinori Sakao (653713), Mingyon Mun (653715), Hiroaki Kuroda (653714), Hirofumi Uehara (653716), Sakae Okumura (653719), Noriko Motoi (653717), Ken Nakagawa (5319)   +7 more
core   +1 more source