Results 111 to 120 of about 403,412 (304)

A Transgenic Prox1-Cre-tdTomato Reporter Mouse for Lymphatic Vessel Research [PDF]

, 2015
The lymphatic vascular system plays an active role in immune cell trafficking, inflammation and cancer spread. In order to provide an in vivo tool to improve our understanding of lymphatic vessel function in physiological and pathological conditions, we ...
Seidel, Catharina D., Ailsa J Christiansen, Roberta Bianchi (717800), Detmar, Michael, Taija Mäkinen, Mäkinen, Taija,, Proulx, Steven T., Detmar, Michael J., Cornelia Halin (574950), Christiansen, Ailsa J., Halin, Cornelia, Ruelicke, Thomas, Catharina D Seidel, Proulx, Steven T, Cornelia Halin, Teijeira, Alvaro, Roberta Bianchi, Ailsa J. Christiansen (717802), Mäkinen, Taija, Hägerling, René, Haegerling, Rene, Christiansen, Ailsa J, Bianchi, Roberta, Seidel, Catharina D, Thomas Rülicke (82172), Rülicke, Thomas, René Hägerling (717805), Alvaro Teijeira, Alvaro Teijeira (717801), Steven T Proulx, Catharina D. Seidel (717803), René Hägerling, Thomas Rülicke, Michael Detmar, Taija Mäkinen (717804), Steven T. Proulx (548964), Michael Detmar (121380)   +36 more
core   +2 more sources

Tumor Mechanical Remodeling via Bidirectional Calcium Redistribution Enables Deep Photothermal‐Immunotherapy

Advanced Science, EarlyView.
A bidirectional calcium‑redistributing nanomodulator rewires intra‑extracellular calcium homeostasis to remodel tumor mechanical microenvironments. It softens tumor stroma to facilitate deep tissue penetration while stiffening tumor cells, evoking amplified immunogenic cell death and robust CTL infiltration, which achieves potent deep photothermal ...
Hongjuan Zhao, Jinpei Sun, Chenxi Zhao, Yuting Cang, Keyu Zong, Yuxin Guo, Yajing Wang, Di Meng, Qingling Song, Lei Wang   +9 more
wiley   +1 more source

Whole Slide Quantification of Stromal Lymphatic Vessel Distribution and Peritumoral Lymphatic Vessel Density in Early Invasive Cervical Cancer: A Method Description [PDF]

, 2011
peer reviewedPeritumoral Lymphatic Vessel Density (LVD) is considered to be a predictive marker for the presence of lymph node metastases in cervical cancer.
Foidart, Jean Michel, J. M. Foidart, Goffin, F., Noel, A., Blacher, S., Signolle, N, S. Blacher, Signolle, N., Kridelka, F., F. Goffin, GOFFIN, Frédéric, A. Beliard, N. Signolle, Balsat, Cédric, Foidart, J. M., C. Balsat, Balsat, C., C. Munaut, Munaut, C., BELIARD, Aude, Signolle, Nicolas, Foidart, Jean-Michel, A. Noel, Beliard, A., F. Kridelka, Noël, Agnès, Munaut, Carine, Blacher, Silvia, Kridelka, Frédéric   +28 more
core   +1 more source

Non‐Invasively Quantitative Raman Imaging for Calculation of Lymphatic Transport Kinetics of Micelles in Mice

Advanced Science, EarlyView.
Non‐invasively quantitative Raman imaging with stacking‐induced charge transfer‐enhanced Raman scattering (SICTERS) enables accurate measurement of concentrations and pharmacokinetic modeling of lymphatic transport of micelles in mice. This platform allows dynamic analysis of nanoparticle transport and underpins the design of effective lymph node ...
Yunlu Li, Hongzheng Lin, Sheng Yu, Yunhui Liao, Teng Huang, Zeyu Xiao, Wei Lu   +6 more
wiley   +1 more source

Changes in the desmosomes of lymphatic vessel endothelial cells as shown by electron microscopy.

, 2013
(a) Desmosomes in the normal type. In a three-dimensional structure, they adhere to the adjacent lymphatic vessel endothelial cells. Bar = 2 µm. (a’) Magnified image. Bar = 2 µm.
Takeshi Todokoro (314536), Noriyuki Murai (160386), Hisako Hara (160364), Taro Okitsu (160391), Takuya Iida (160381), Jun Araki (138191), Kazuki Kikuchi (160371), Makoto Mihara (138200), Isao Koshima (138203), Iori Kisu (170427), Mitsunaga Narushima (160375), Yohei Hayashi (236734), Takumi Yamamoto (160379), Naoya Sawamoto (314538)   +13 more
core   +1 more source

VEGF family members : modulators of tumor angiogenesis and lymphangiogenesis [PDF]

, 2006
Members of the vascular endothelial growth factor (VEGF) family and their receptors (VEGFR) play an essential role in the development and maintenance of the blood and lymphatic vasculature.
Kopfstein, Lucie
core   +1 more source

Structural Basis of Lymphangiogenic Receptor VEGFR‐3 Activation Mediated by Distinctive Clustering of the Ligand–Receptor Complex

Advanced Science, EarlyView.
VEGF‐C and its receptor VEGFR‐3 are critical for lymphangiogenesis. Cryo‐EM structures of the VEGFR‐3/VEGF‐C ectodomain complex reveal a canonical 2:2 ligand–receptor hetero‐tetramer that further assembles into higher‐order clusters beyond simple receptor dimerization.
Ryeongeun Cho, Jinsook Ahn, Jimin Yang, Dong Sun Lee, Gahi Hong, Sangkyu Lee, Ho Min Kim   +6 more
wiley   +1 more source

New Microcannulation Technique for Imaging Contrast and Drug Delivery via the Lymphatics

Plastic and Reconstructive Surgery, Global Open
Summary:. A technique for drug delivery using the lymphatics was introduced and tested in animals half a century ago, but was never trialed in human subjects. Recently, surgical manipulation of lymphatic vessels for lymphedema treatment has attracted the
Hiroo Suami, MD, PhD
doaj   +1 more source

Comparison of Minimally Invasive Colectomy Between Intra‐ Versus Extra‐Corporeal Anastomosis Technique (COMMIT Study): Short‐Term Analysis

Annals of Gastroenterological Surgery, EarlyView.
This multicenter propensity score‐matched study of 3213 patients compared intracorporeal (IA) and extracorporeal (EA) anastomosis during minimally invasive colectomy. IA was associated with a significantly lower incidence of intraoperative blood loss ≥ 200 mL (2.5% vs.
Takuya Takami, Takehito Yamamoto, Yoshiro Itatani, Ryosuke Mizuno, Kae Okoshi, Yasunori Deguchi, Keiji Nagata, Tomoaki Okada, Rei Mizuno, Kazutaka Obama   +9 more
wiley   +1 more source

Impact of Histopathological Response on Outcomes After Surgical Resection Following Carbon‐Ion Radiotherapy for Pancreatic Cancer With Arterial Involvement

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Carbon‐ion radiotherapy (CIRT) provides superior dose distribution and higher biological effectiveness than conventional X‐ray radiotherapy and has emerged as a promising component of multidisciplinary treatment for advanced pancreatic ductal adenocarcinoma (PDAC).
Kenichiro Araki, Norio Kubo, Yuhei Miyasaka, Hayato Ikota, Ryo Muranushi, Mariko Tsukagoshi, Takamichi Igarashi, Masahiko Okamoto, Tatsuya Ohno, Ken Shirabe   +9 more
wiley   +1 more source