Results 121 to 130 of about 1,026,018 (392)

VEGF-C is required for intestinal lymphatic vessel maintenance and lipid absorption

open access: yesEMBO Molecular Medicine, 2015
Vascular endothelial growth factor C (VEGF‐C) binding to its tyrosine kinase receptor VEGFR‐3 drives lymphatic vessel growth during development and in pathological processes.
H. Nurmi   +5 more
semanticscholar   +1 more source

Therapeutic Antibodies for Mosquito‐Borne Orthoflavivirus Infections: Discovery, Engineering Approaches, and Advances in mRNA‐Based Delivery Systems

open access: yesAdvanced Therapeutics, EarlyView.
This review explores how antibody engineering and display technologies are driving therapeutic advances against mosquito‐borne orthoflaviviruses such as Zika, dengue, and yellow fever viruses. It highlights diverse neutralizing targets on the envelope protein, including the conserved fusion loop, and discusses how Fc engineering, rational antigen ...
Ana Clara Barbosa Antonelli   +5 more
wiley   +1 more source

How useful is the assessment of lymphatic vascular density in oral carcinoma prognosis?

open access: yesWorld Journal of Surgical Oncology, 2007
Background Lymphatic vessels are major routes for metastasis in head and neck squamous cell carcinoma (HNSCC), but lymphatic endothelial cells (LECs) are difficult to recognize in tumor histological sections. D2-40 stains podoplanin, a molecule expressed
Mercante Ana   +7 more
doaj   +1 more source

Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis

open access: yesAdvanced Science, EarlyView.
The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li   +12 more
wiley   +1 more source

Limfangiogenesis sebagai jalur alternatif metastasis kanker

Lymphangiogenesis as an alternative pathway for cancer metastasis

open access: yesJurnal Kedokteran Gigi Universitas Padjadjaran, 2016
Pendahuluan: Metastasis merupakan salah satu sifat kanker yang dapat terjadi melalui berbagai cara yaitu melalui rongga tubuh, melalui pembuluh limfatik, dan melalui pembuluh darah. Pembuluh limfatik merupakan jalur penting dalam metastasis kanker karena
Pudji Handayani   +2 more
doaj   +1 more source

Lymphendothel in terminaler Herzinsuffizienz und nach Herz- und Lungentransplantation [PDF]

open access: yes, 2017
The lymphatic endothelium is relevant for the pathogenesis of various cardiac and pulmonary diseases. However, the knowledge about the functions and role of lymphatic endothelium in the setting of transplantation is very limited.
Dashkevich, Alexey
core  

A Mathematical Model for Lymphangiogenesis in Normal and Diabetic Wounds

open access: yes, 2015
Several studies suggest that one possible cause of impaired wound healing is failed or insufficient lymphangiogenesis, that is the formation of new lymphatic capillaries.
Bianchi, Arianna   +2 more
core   +1 more source

Rapid Lymphatic Dissemination of Encapsulated Group A Streptococci via Lymphatic Vessel Endothelial Receptor-1 Interaction

open access: yesPLoS Pathogens, 2015
The host lymphatic network represents an important conduit for pathogen dissemination. Indeed, the lethal human pathogen group A streptococcus has a predilection to induce pathology in the lymphatic system and draining lymph nodes, however the underlying
N. Lynskey   +8 more
semanticscholar   +1 more source

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

open access: yesAdvanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao   +9 more
wiley   +1 more source

Multiscale modelling of fluid and solute transport in soft tissues and microvessels [PDF]

open access: yes, 2010
This study focuses on the movement of particles and extracellular fluid in soft tissues and microvessels. It analyzes modeling applications in biological and physiological fluids at a range of different length scales: from between a few tens to several ...
Lu, Yiling, Wang, Wen
core   +2 more sources

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