Results 171 to 180 of about 1,011,532 (393)

Novel application assigned to toluquinol: inhibition of lymphangiogenesis by interfering with VEGF-C/VEGFR-3 signalling pathway [PDF]

open access: yes, 2016
BACKGROUND AND PURPOSE Lymphangiogenesis is an important biological process associated with the pathogenesis of several diseases, including metastatic dissemination, graft rejection, lymphoedema and other inflammatory disorders.
Blacher, S.   +5 more
core  

AUTOTRANSPLANTATION OF LYMPHATIC VESSELS

open access: yesThe Lancet, 1981
Baumeister, Rüdiger   +2 more
openaire   +3 more sources

Comprehensive Insights into Tracheoesophageal Fistula Pathophysiology, Diagnosis, Treatment, and Future Directions

open access: yesAdvanced Science, EarlyView.
Tracheoesophageal fistula (TEF), a pathological trachea‐esophagus connection, arises congenitally or from malignancy/radiotherapy/trauma, causing aspiration and malnutrition. Diagnosis utilizes imaging and endoscopy. Treatment ranges from endoscopic stenting to surgical repair and conservative management.
Gang Li   +10 more
wiley   +1 more source

Development of flow focusing device for the visualization of leukocyte rolling adhesion [PDF]

open access: yes, 2018
La microfluídica es un área de la microtecnología basada en chips de PDMS que está siendo utilizada cada vez más en multitud de aplicaciones. Una de estas aplicaciones es la investigación biomédica.
Morales Navarrete, Pablo
core  

Deciphering the Role and Mechanism of Decidual Monocyte‐Derived Macrophage Infiltration in Obstetric Antiphospholipid Syndrome at Single‐Cell Resolution

open access: yesAdvanced Science, EarlyView.
This study uncovers a novel mechanism and therapeutic targets in obstetric antiphospholipid syndrome (OAPS). Antiphospholipid antibody/ß2‐glycoprotein I complex boosts CCL2 and TNF‐α expression in decidual macrophages via TLR4‐NF‐κB. CCL2 accumulates on endothelial surfaces via ACKR1, recruiting monocyte‐derived CCR2+ macrophages, driving inflammation,
Rui Gao   +13 more
wiley   +1 more source

Autophagy‐Mediated Suppression of Tumor Growth by Food‐Grade Lipid Nanoparticles in Mice

open access: yesAdvanced Science, EarlyView.
This work reveals a novel extracellular nanoparticle transport and metabolic pathway. Following cellular uptake, Food‐grade lipid nanoparticles (FLNs) selectively fuse with lipid droplets (LDs) rather than lysosomes, driving LDs accumulation. This process activates autophagy through the AMPK‐mTOR‐ULK1 signaling axis, facilitating tumor progression ...
Chenglu Peng   +10 more
wiley   +1 more source

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