Results 41 to 50 of about 1,026,018 (392)

Tumor-Associated Lymphatic Vessel Features and Immunomodulatory Functions

Frontiers in Immunology, 2019
The lymphatic system comprises a network of lymphoid tissues and vessels that drains the extracellular compartment of most tissues. During tumor development, lymphatic endothelial cells (LECs) substantially expand in response to VEGFR-3 engagement by ...
L. Garnier, A. Gkountidi, S. Hugues
semanticscholar   +1 more source

Lymphatic vessels in health and disease [PDF]

WIREs Systems Biology and Medicine, 2012
AbstractThe lymphatic vasculature plays vital roles in tissue fluid balance, immune defense, metabolism, and cancer metastasis. In adults, lymphatic vessel formation and remodeling occur primarily during inflammation, development of the corpus luteum, wound healing, and tumor growth.
Cristina T, Kesler, Shan, Liao, Lance L, Munn, Timothy P, Padera   +3 more
openaire   +2 more sources

Clinical implications of increased lymph vessel density in the lymphatic metastasis of early-stage invasive cervical carcinoma: a clinical immunohistochemical method study

BMC Cancer, 2009
Background Cervical cancer is the most common malignant gynecological cancer, and lymphatic metastasis can occur in the early stage of tumor growth. Lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1), a marker for lymphatic endothelium, provides
Yu Hao, Zhang Shi-qian, Zhang Lin-lin
doaj   +1 more source

Lymphangiography to treat postoperative lymphatic leakage: a technical review. [PDF]

, 2014
In addition to imaging the lymphatics and detecting various types of lymphatic leakage, lymphangiography is a therapeutic option for patients with chylothorax, chylous ascites, and lymphatic fistula.
Kim, Soo Hwan, Ko, Heung Kyu, Lee, Edward Wolfgang, Park, Jihong, Shin, Ji Hoon, Sung, Kyu-Bo   +5 more
core   +1 more source

Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program

Nature Communications, 2018
Tissue and vessel wall stiffening alters endothelial cell properties and contributes to vascular dysfunction. However, whether extracellular matrix (ECM) stiffness impacts vascular development is not known.
Maike Frye, Andrea Taddei, Cathrin Dierkes, I. Martinez-Corral, M. Fielden, H. Ortsäter, J. Kazenwadel, D. Calado, P. Ostergaard, M. Salminen, Liqun He, N. Harvey, F. Kiefer, Taija Mäkinen   +13 more
semanticscholar   +1 more source

Microanatomical organization of hepatic venous lymphatic system in humans.

PLoS ONE, 2023
Lymphatic fluid drains from the liver via the periportal lymphatic, hepatic venous lymphatic, and superficial lymphatic systems. We performed a postmortem study to clarify the three-dimensional structure and flow dynamics of the human hepatic venous ...
Kotaro Umemura, Hiroshi Shimoda, Keinosuke Ishido, Norihisa Kimura, Taiichi Wakiya, Takuji Kagiya, Kentaro Sato, Yuto Mitsuhashi, Seiji Watanabe, Hirokazu Narita, Tomohiro Chiba, Kenichi Hakamada   +11 more
doaj   +2 more sources

The role of VEGF-C/D and Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma

Journal of Experimental & Clinical Cancer Research, 2009
Background To investigate the role of vascular endothelial growth factors (VEGF)-C/D and their receptor Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma.
Zhang Renhua, Zhang Shiqian, Yu Hao, Zhang Linlin   +3 more
doaj   +1 more source

Perspectives in Microvascular Fluid Handling: Does the Distribution of Coagulation Factors in Human Myocardium Comply with Plasma Extravasation in Venular Coronary Segments? [PDF]

, 2010
Background: Heterogeneity of vascular permeability has been suggested for the coronary system. Whereas arteriolar and capillary segments are tight, plasma proteins pass readily into the interstitial space at venular sites.
Becker, Bernhard F., Bruegger, Dirk, Chappell, Daniel, Conzen, Peter, Jacob, Matthias, Kaczmarek, Ingo, Rehm, Markus, Stoeckelhuber, Mechthild, Welsch, Ulrich   +8 more
core   +1 more source

Confocal Imaging: Blood and Lymphatic Capillaries

The Scientific World Journal, 2006
Traditional imaging techniques are quite limited for the study of the relationship between blood vessels and lymphatic vessels. Therefore, a new imaging technique is required based on blood vessel and lymphatic endothelial-specific molecular markers.
Yingjie Cui
doaj   +1 more source

Protocol for in vivo and in vitro study of lymphatic valve formation driven by shear stress signaling pathway

STAR Protocols, 2023
Summary: Here we detail a protocol for the isolation and processing of lymphatic enriched tissue of mouse models for the purpose of immunostaining and quantification of lymphatic valves, vessel length, and vessel diameter.
Richa Banerjee, Luz A. Knauer, Ying Yang
doaj   +1 more source