Results 41 to 50 of about 968,485 (355)

Lymphatic vessel density is associated with CD8+ T cell infiltration and immunosuppressive factors in human melanoma

Oncoimmunology, 2018
Increased density of tumor-associated lymphatic vessels correlates with poor patient survival in melanoma and other cancers, yet lymphatic drainage is essential for initiating an immune response.
N. Bordry, Maria A. S. Broggi, Kaat de Jonge, Karin Schaeuble, P. Gannon, P. Foukas, E. Danenberg, E. Romano, Petra Baumgaertner, M. Fankhauser, N. Wald, Laurène Cagnon, S. Abed-Maillard, H. Maby-El Hajjami, T. Murray, Kalliopi Ioannidou, I. Letovanec, P. Yan, O. Michielin, M. Matter, M. Swartz, D. Speiser   +21 more
semanticscholar   +1 more source

Clinical implications of increased lymph vessel density in the lymphatic metastasis of early-stage invasive cervical carcinoma: a clinical immunohistochemical method study

BMC Cancer, 2009
Background Cervical cancer is the most common malignant gynecological cancer, and lymphatic metastasis can occur in the early stage of tumor growth. Lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1), a marker for lymphatic endothelium, provides
Yu Hao, Zhang Shi-qian, Zhang Lin-lin
doaj   +1 more source

Solute Transport across the Lymphatic Vasculature in a Soft Skin Tissue

Biology, 2023
Convective transport of drug solutes in biological tissues is regulated by the interstitial fluid pressure, which plays a crucial role in drug absorption into the lymphatic system through the subcutaneous (SC) injection.
Dingding Han, Ziyang Huang, Ehsan Rahimi, Arezoo M. Ardekani   +3 more
doaj   +1 more source

Confocal Imaging: Blood and Lymphatic Capillaries

The Scientific World Journal, 2006
Traditional imaging techniques are quite limited for the study of the relationship between blood vessels and lymphatic vessels. Therefore, a new imaging technique is required based on blood vessel and lymphatic endothelial-specific molecular markers.
Yingjie Cui
doaj   +1 more source

Lymphangiogenesis Guidance Mechanisms and Therapeutic Implications in Pathological States of the Cornea

Cells, 2023
Corneal lymphangiogenesis is one component of the neovascularization observed in several inflammatory pathologies of the cornea including dry eye disease and corneal graft rejection.
Mehul Patnam, Sunil R. Dommaraju, Faisal Masood, Paula Herbst, Jin-Hong Chang, Wen-Yang Hu, Mark I. Rosenblatt, Dimitri T. Azar   +7 more
doaj   +1 more source

Digging deeper into lymphatic vessel formation in vitro and in vivo

BMC Cell Biology, 2011
Background Abnormal lymphatic vessel formation (lymphangiogenesis) is associated with different pathologies such as cancer, lymphedema, psoriasis and graft rejection.
Thiry Marc, Foidart Jean-Michel, Lenoir Bénédicte, Maillard Catherine, Lamaye Françoise, Paupert Jenny, Erpicum Charlotte, Bruyère Françoise, Detry Benoit, Noël Agnès   +9 more
doaj   +1 more source

Methicillin-resistant Staphylococcus aureus causes sustained collecting lymphatic vessel dysfunction

Science Translational Medicine, 2018
Impairment in lymph flow caused by methicillin-resistant Staphylococcus aureus toxins persists after skin and soft tissue infections clear. Lymphatics limp along after MRSA Lymphedema is associated with skin and soft tissue infections, and both can be ...
Dennis Jones, Eelco F. J. Meijer, C. Blatter, S. Liao, E. Pereira, E. Bouta, K. Jung, S. Chin, Peigen Huang, L. Munn, B. Vakoc, M. Otto, T. Padera   +12 more
semanticscholar   +1 more source

Pathophysiology of aged lymphatic vessels

Aging, 2019
Lymphatic vessels maintain body homeostasis by recirculation of fluid and cells. Cell senescence induces lymphatic dysfunction. Impaired contractile function is caused by low muscle cell investiture and decrease of nitric oxide in aged lymphatic collectors, leading to poor drainage of lymph.
Jiangjiu Liang, Tongyao Shang, Ju Liu, Carolyn M. Kapron   +3 more
openaire   +3 more sources

Structure-preserving semi-convex-splitting numerical scheme for a Cahn-Hilliard cross-diffusion system in lymphangiogenesis [PDF]

arXiv, 2023
A fully discrete semi-convex-splitting finite-element scheme with stabilization for a Cahn-Hilliard cross-diffusion system is analyzed. The system consists of parabolic fourth-order equations for the volume fraction of the fiber phase and solute concentration, modeling pre-patterning of lymphatic vessel morphology.
arxiv  

Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction

Scientific Reports, 2018
Heart has a wide lymphatic network but the importance of cardiac lymphatic system in heart diseases has remained unclear. Vascular Endothelial Growth Factor Receptor 3 (VEGFR3) is a key molecule in the development and maintenance of cardiac lymphatic ...
Taina Vuorio, Elias Ylä-Herttuala, J. Laakkonen, S. Laidinen, T. Liimatainen, S. Ylä-Herttuala   +5 more
semanticscholar   +1 more source