Results 31 to 40 of about 50,398 (261)

Lymphatic vessels in health and disease [PDF]

WIREs Systems Biology and Medicine, 2012
AbstractThe lymphatic vasculature plays vital roles in tissue fluid balance, immune defense, metabolism, and cancer metastasis. In adults, lymphatic vessel formation and remodeling occur primarily during inflammation, development of the corpus luteum, wound healing, and tumor growth.
Cristina T, Kesler, Shan, Liao, Lance L, Munn, Timothy P, Padera   +3 more
openaire   +2 more sources

Effects of MEK-inhibitor treatment in infants with lymphatic abnormalities in noonan syndrome

Frontiers in Pediatrics
Noonan syndrome (NS) is a genetic disorder associated with dysregulation of the RAS/MAPK signaling pathway and is frequently accompanied by lymphatic abnormalities.
J. Wagenpfeil, J. Wagenpfeil, K. Hoß, A. Henkel, D. L. Kütting, J. A. Luetkens, A. Mueller, A. Mueller, C. C. Pieper, C. C. Pieper, A. Groteklaes, A. Groteklaes   +11 more
doaj   +1 more source

Clinical implications of increased lymph vessel density in the lymphatic metastasis of early-stage invasive cervical carcinoma: a clinical immunohistochemical method study

BMC Cancer, 2009
Background Cervical cancer is the most common malignant gynecological cancer, and lymphatic metastasis can occur in the early stage of tumor growth. Lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1), a marker for lymphatic endothelium, provides
Yu Hao, Zhang Shi-qian, Zhang Lin-lin
doaj   +1 more source

Confocal Imaging: Blood and Lymphatic Capillaries

The Scientific World Journal, 2006
Traditional imaging techniques are quite limited for the study of the relationship between blood vessels and lymphatic vessels. Therefore, a new imaging technique is required based on blood vessel and lymphatic endothelial-specific molecular markers.
Yingjie Cui
doaj   +1 more source

Digging deeper into lymphatic vessel formation in vitro and in vivo

BMC Cell Biology, 2011
Background Abnormal lymphatic vessel formation (lymphangiogenesis) is associated with different pathologies such as cancer, lymphedema, psoriasis and graft rejection.
Thiry Marc, Foidart Jean-Michel, Lenoir Bénédicte, Maillard Catherine, Lamaye Françoise, Paupert Jenny, Erpicum Charlotte, Bruyère Françoise, Detry Benoit, Noël Agnès   +9 more
doaj   +1 more source

Microfluidic System to Analyze the Effects of Interleukin 6 on Lymphatic Breast Cancer Metastasis

Frontiers in Bioengineering and Biotechnology, 2021
Metastasis is the primary cause of a large number of cancer-associated deaths. By portraying the precise environment of the metastasis process in vitro, the microfluidic system provides useful insights on the mechanisms underlying cancer cell migration ...
Hyeon-Yeol Cho, Hyeon-Yeol Cho, Jin-Ha Choi, Kyeong-Jun Kim, Minkyu Shin, Jeong-Woo Choi   +5 more
doaj   +1 more source

Lymphatic Vessels and Their Surroundings: How Local Physical Factors Affect Lymph Flow

Biology, 2020
Lymphatic vessels drain and propel lymph by exploiting external forces that surrounding tissues exert upon vessel walls (extrinsic mechanism) and by using active, rhythmic contractions of lymphatic muscle cells embedded in the vessel wall of collecting ...
Eleonora Solari, Cristiana Marcozzi, Daniela Negrini, Andrea Moriondo   +3 more
doaj   +1 more source

Protocol for in vivo and in vitro study of lymphatic valve formation driven by shear stress signaling pathway

STAR Protocols, 2023
Summary: Here we detail a protocol for the isolation and processing of lymphatic enriched tissue of mouse models for the purpose of immunostaining and quantification of lymphatic valves, vessel length, and vessel diameter.
Richa Banerjee, Luz A. Knauer, Ying Yang
doaj   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Microanatomical organization of hepatic venous lymphatic system in humans.

PLoS ONE, 2023
Lymphatic fluid drains from the liver via the periportal lymphatic, hepatic venous lymphatic, and superficial lymphatic systems. We performed a postmortem study to clarify the three-dimensional structure and flow dynamics of the human hepatic venous ...
Kotaro Umemura, Hiroshi Shimoda, Keinosuke Ishido, Norihisa Kimura, Taiichi Wakiya, Takuji Kagiya, Kentaro Sato, Yuto Mitsuhashi, Seiji Watanabe, Hirokazu Narita, Tomohiro Chiba, Kenichi Hakamada   +11 more
doaj   +2 more sources