Results 31 to 40 of about 84,333 (303)

Lymphatic vessels in health and disease [PDF]

WIREs Systems Biology and Medicine, 2012
AbstractThe lymphatic vasculature plays vital roles in tissue fluid balance, immune defense, metabolism, and cancer metastasis. In adults, lymphatic vessel formation and remodeling occur primarily during inflammation, development of the corpus luteum, wound healing, and tumor growth.
Cristina T, Kesler, Shan, Liao, Lance L, Munn, Timothy P, Padera   +3 more
openaire   +2 more sources

Network development in biological gels: role in lymphatic vessel development [PDF]

, 2008
In this paper, we present a model that explains the prepatterning of lymphatic vessel morphology in collagen gels. This model is derived using the theory of two phase rubber material due to Flory and coworkers and it consists of two coupled fourth order ...
Fowler, A. C., Roose, Tiina
core   +3 more sources

VIPAR, a quantitative approach to 3D histopathology applied to lymphatic malformations. [PDF]

, 2017
BACKGROUND: Lack of investigatory and diagnostic tools has been a major contributing factor to the failure to mechanistically understand lymphedema and other lymphatic disorders in order to develop effective drug and surgical therapies.
Butz, S, Dierkes, C, Drees, D, Goerge, T, Gordon, K, Hinrichs, K, Hägerling, R, Jiang, X, Kiefer, F, Mansour, S, Martin-Almedina, S, Mortimer, PS, Ostergaard, P, Scherzinger, A, Schäfers, M, Vestweber, D   +15 more
core   +1 more source

Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early Rheumatoid Arthritis: an observational study. [PDF]

, 2015
INTRODUCTION: Neovascularization contributes to the development of sustained synovial inflammation in the early stages of Rheumatoid Arthritis. Ultrasound (US) provides an indirect method of assessing synovial blood flow and has been shown to correlate ...
AE Koch, AE Koch, Alessandra Marrelli, Arti Mahto, AW Mould, Costantino Pitzalis, Debasish Pyne, E Bodolay, Frances Humby, J Holash, J Holash, K Polzer, Lu Zou, M Andersen, M Raica, M Walther, M Walther, Maria DiCicco, Michele Bombardieri, Nora Ng, P Haiko, PP Tak, Rebecca E Hands, S Kelly, S Lee, Stephen Kelly, Sudeh Riahi, U Fiocco, U Fiocco, V Krenn, WA Schmidt, Y Jing, Y Xu, Z Szekanecz   +33 more
core   +2 more sources

Clinical implications of increased lymph vessel density in the lymphatic metastasis of early-stage invasive cervical carcinoma: a clinical immunohistochemical method study

BMC Cancer, 2009
Background Cervical cancer is the most common malignant gynecological cancer, and lymphatic metastasis can occur in the early stage of tumor growth. Lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1), a marker for lymphatic endothelium, provides
Yu Hao, Zhang Shi-qian, Zhang Lin-lin
doaj   +1 more source

The role of VEGF-C/D and Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma

Journal of Experimental & Clinical Cancer Research, 2009
Background To investigate the role of vascular endothelial growth factors (VEGF)-C/D and their receptor Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma.
Zhang Renhua, Zhang Shiqian, Yu Hao, Zhang Linlin   +3 more
doaj   +1 more source

Three-Dimensional In Vitro Lymphangiogenesis Model in Tumor Microenvironment

Frontiers in Bioengineering and Biotechnology, 2021
Lymphangiogenesis is a stage of new lymphatic vessel formation in development and pathology, such as inflammation and tumor metastasis. Physiologically relevant models of lymphatic vessels have been in demand because studies on lymphatic vessels are ...
Youngkyu Cho, Youngkyu Cho, Kyuhwan Na, Yesl Jun, Yesl Jun, Jihee Won, Ji Hun Yang, Ji Hun Yang, Seok Chung, Seok Chung   +9 more
doaj   +1 more source

MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and suppresses VEGF-C production to inhibit lymphangiogenesis [PDF]

, 2016
Lymphangiogensis is involved in various pathological conditions, such as arthritis and cancer metastasis. Although many factors have been identified to stimulate lymphatic vessel growth, little is known about lymphangiogenesis inhibitors.
Cao, R, Cao, Y, Jin, G, Wong, HLX, Zhang, S, Zhou, Z   +5 more
core   +1 more source

High lymphatic vessel density and presence of lymphovascular invasion both predict poor prognosis in breast cancer

BMC Cancer, 2017
Background Lymphatic vessel density and lymphovascular invasion are commonly assessed to identify the clinicopathological outcomes in breast cancer. However, the prognostic values of them on patients’ survival are still uncertain.
Song Zhang, Dong Zhang, Mingfu Gong, Li Wen, Cuiwei Liao, Liguang Zou   +5 more
doaj   +1 more source

Perspectives in Microvascular Fluid Handling: Does the Distribution of Coagulation Factors in Human Myocardium Comply with Plasma Extravasation in Venular Coronary Segments? [PDF]

, 2010
Background: Heterogeneity of vascular permeability has been suggested for the coronary system. Whereas arteriolar and capillary segments are tight, plasma proteins pass readily into the interstitial space at venular sites.
Becker, Bernhard F., Bruegger, Dirk, Chappell, Daniel, Conzen, Peter, Jacob, Matthias, Kaczmarek, Ingo, Rehm, Markus, Stoeckelhuber, Mechthild, Welsch, Ulrich   +8 more
core   +1 more source