Results 41 to 50 of about 50,398 (261)

Hydrogel Microtube Drug Carrier for Catheter‐Based Intravascular Therapy

Advanced Healthcare Materials, EarlyView.
This paper proposes hydrogel microtube carriers composed of barium alginate gel, enabling long‐term vascular retention without interrupting blood flow. Intravascular treatments have long been attracting attention for therapeutic efficacy, yet practical delivery methods remained unestablished.
Shota Sato, Hiroki Ohta, Naoki Takakura, Kentaro Kasa, Teppei Komatsu, Dai Kejia, Misato Yoshioka, Hirotaka James Okano, Hiroaki Onoe   +8 more
wiley   +1 more source

Solute Transport across the Lymphatic Vasculature in a Soft Skin Tissue

Biology, 2023
Convective transport of drug solutes in biological tissues is regulated by the interstitial fluid pressure, which plays a crucial role in drug absorption into the lymphatic system through the subcutaneous (SC) injection.
Dingding Han, Ziyang Huang, Ehsan Rahimi, Arezoo M. Ardekani   +3 more
doaj   +1 more source

Nanoplatforms for Sentinel and Tumor‐Draining Lymph Node Mapping: From Visualization to Pathway‐Informed Staging

Advanced Healthcare Materials, EarlyView.
Lymphotropic nanoplatforms integrate multimodal imaging with therapeutic guidance to map sentinel and tumor‐draining lymph nodes, revealing functional drainage, metastatic involvement, and nodal accessibility, while providing mechanistic insight to support precision surgical and therapeutic interventions.
Xu Chen, Nina Li, Meiyan Zou, Zihao Zhou, Rongwei Xu, Weiyao Feng, Xinyuan Zhao, Li Cui   +7 more
wiley   +1 more source

Lymphangiogenesis Guidance Mechanisms and Therapeutic Implications in Pathological States of the Cornea

Cells, 2023
Corneal lymphangiogenesis is one component of the neovascularization observed in several inflammatory pathologies of the cornea including dry eye disease and corneal graft rejection.
Mehul Patnam, Sunil R. Dommaraju, Faisal Masood, Paula Herbst, Jin-Hong Chang, Wen-Yang Hu, Mark I. Rosenblatt, Dimitri T. Azar   +7 more
doaj   +1 more source

Mouse Brain Lymphatic Vessels

ACS Chemical Neuroscience
Abstract The lymphatic system plays a vital role in immune function and waste removal, yet its involvement in the brain has remained largely unexplored. This study provides compelling evidence of lymphatic vessels in the mouse brain, specifically in the cortex, thalamus, and hippocampus.
Amin Tamadon, Alireza Afshar, Nadiar M. Mussin, Kulyash R. Zhilisbayeva, Madina A. Kurmanalina, Akmaral Baspakova, Raisa A. Aringazina, Mahdi Mahdipour, Nader Tanideh, Arezoo Khoradmehr, Mostafa Najarasl, Payam Taheri   +11 more
openaire   +2 more sources

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

A 3D Human Bone and Bone Marrow‐on‐a‐Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance

Advanced Science, EarlyView.
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer, Melanie‐Jasmin Ort, Kristian Händler, Emely Bortel, Ioanna Maria Dimitriou, Martin Textor, Georg N. Duda, Janosch Schoon, Uwe Marx, Uwe Kornak, Annika Winter, Bernhard Hesse, Stefanie Donner, Sebastian Hardt, Oliver Klein, Simon Reinke, Malte Spielmann, Sven Geißler   +17 more
wiley   +1 more source

Lymphatic Mapping for LVA with Noncontrast Lymphatic Ultrasound: How We Do It

Plastic and Reconstructive Surgery, Global Open
Summary:. Recently, lymphatic ultrasonography has received increasing attention. Although there are several reports on contrast-enhanced lymphatic ultrasound as a preoperative examination for lymphaticovenous anastomosis (LVA), we have been reporting the
Hisako Hara, MD, PhD, Michiru Ichinose, RN, Fumika Shimomura, RN, Mari Kawahara, MD, Makoto Mihara, MD   +4 more
doaj   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

Insulin-like growth factor signaling regulates zebrafish lymphatic-vessel development

Cell Reports
Summary: The coordinated migration of lymphatic endothelial cells (LECs) is essential for the development of the lymphatic network. Here, we uncover the role of the insulin-like growth factor (IGF) signaling pathway in zebrafish lymphatic vessel ...
Wenxuan Chen, June P. Misa, Caitlin D. Herbert, Ben Watkin, Taylor J. Stevenson, Samuel J.C. McCullough, Kate L. Lee, Stefan K. Bohlander, Diego J. Hoyle, Philip S. Crosier, Thomas F. Schilling, Justin Rustenhoven, Christopher J. Hall, Jonathan W. Astin   +13 more
doaj   +1 more source