Chronic high-fat diet impairs collecting lymphatic vessel function in mice. [PDF]
PLoS ONE, 2014 Lymphatic vessels play an essential role in intestinal lipid uptake, and impairment of lymphatic vessel function leads to enhanced adipose tissue accumulation in patients with lymphedema and in genetic mouse models of lymphatic dysfunction.
Katrin S Blum +7 more
doaj +3 more sources
Insulin-like growth factor signaling regulates zebrafish lymphatic-vessel development
Cell ReportsSummary: The coordinated migration of lymphatic endothelial cells (LECs) is essential for the development of the lymphatic network. Here, we uncover the role of the insulin-like growth factor (IGF) signaling pathway in zebrafish lymphatic vessel ...
Wenxuan Chen +13 more
doaj +2 more sources
Lymphatic vascular response to acute inflammation. [PDF]
PLoS ONE, 2013 During acute inflammation, functioning lymphatics are believed to reduce edema and to provide a transiting route for immune cells, but the extent at which the dermal lymphatic remodeling impacts lymphatic transport or the factors regulating these changes
Pier-Anne Lachance +2 more
doaj +1 more source
Multiple aspects of lymphatic dysfunction in an ApoE−/− mouse model of hypercholesterolemia
Frontiers in Physiology, 2023 Introduction: Rodent models of cardiovascular disease have uncovered various types of lymphatic vessel dysfunction that occur in association with atherosclerosis, type II diabetes and obesity.
Michael J. Davis +8 more
doaj +1 more source
Lymphatic vascular morphogenesis in development, physiology, and disease [PDF]
, 2011 The lymphatic vasculature constitutes a highly specialized part of the vascular system that is essential for the maintenance of interstitial fluid balance, uptake of dietary fat, and immune response. Recently, there has been an increased awareness of the
Amélie Sabine +6 more
core +3 more sources
Tumor-induced myeloid cell plasticity toward lymphatic endothelium [PDF]
, 2009 Tumor-associated lymphangiogenesis contributes to tumor progression by regulating interstitial fluid pressure, transporting immune cells to the tumor site and providing a route for metastatic dissemination.
Baeriswyl, Vanessa
core +1 more source
Characterization, Localization and Patterning of Lymphatics and Blood Vessels in Oral Squamous Cell Carcinoma: A Comparative Study Using D2-40 and CD-34 IHC Marker [PDF]
Journal of Clinical and Diagnostic Research, 2014 Objectives: Lymphatic metastasis has always been regarded as a major prognostic indicator for disease progression and as a guide for therapeutic strategies to oral squamous cell carcinoma (OSCC).
Deshant Agarwal +7 more
doaj +1 more source
Size adjustment suture technique for lymphaticovenular anastomosis
Journal of Plastic Surgery and Hand Surgery, 2023 In this report, we describe a super microsurgical technique that enables rapid and accurate anastomosis while adjusting for caliber differences when anastomosing a small-caliber lymphatic vessel and a vein with a larger caliber, which is frequently ...
Satoshi Onoda +2 more
doaj +1 more source
A Role for All-Trans-Retinoic Acid in the Early Steps of Lymphatic Vasculature Development [PDF]
, 2010 The molecular mechanisms that regulate the earliest steps of lymphatic vascular system development are unknown. To identify regulators of lymphatic competence and commitment, we used an in vitro vascular assay with mouse embryonic stem cell-derived ...
Dabouras, Vasilios +7 more
core +1 more source
Lymphatic vessels in health and disease [PDF]
WIREs Systems Biology and Medicine, 2012 AbstractThe lymphatic vasculature plays vital roles in tissue fluid balance, immune defense, metabolism, and cancer metastasis. In adults, lymphatic vessel formation and remodeling occur primarily during inflammation, development of the corpus luteum, wound healing, and tumor growth.
Cristina T, Kesler +3 more
openaire +2 more sources