Results 121 to 130 of about 1,092,661 (368)
Role of Lymphatic Vessels in Tumor Immunity: Passive Conduits or Active Participants? [PDF]
, 2018 Research in lymphatic biology and cancer immunology may soon intersect as emerging evidence implicates the lymphatics in the progression of chronic inflammation and autoimmunity as well as in tumor metastasis and immune escape. Like the blood vasculature,
Lund, Amanda, Swartz, Melody
core
T cell egress via lymphatic vessels is tuned by antigen encounter and limits tumor control
Nature Immunology, 2023 M. M. Steele +13 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad +3 more
wiley +1 more source
Tumor-Associated Lymphatic Vessels Upregulate PDL1 to Inhibit T-Cell Activation
Frontiers in Immunology, 2017 Tumor-associated lymphatic vessels (LVs) play multiple roles during tumor progression, including promotion of metastasis and regulation of antitumor immune responses by delivering antigen from the tumor bed to draining lymph nodes (LNs).
L. Dieterich +5 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach +7 more
wiley +1 more source
Effects of ionizing radiation on normal and tumor-associated lymphatic vessels [PDF]
, 2007 Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Nuclear Science and Engineering, 2007."June 2007."Includes bibliographical references (p. 37-43).Lymphatic vessels play a crucial role in both the pathophysiology of tumors and in the spread ...
Lobo, Jennifer D
core
Perspectives in Microvascular Fluid Handling: Does the Distribution of Coagulation Factors in Human Myocardium Comply with Plasma Extravasation in Venular Coronary Segments? [PDF]
, 2010 Background: Heterogeneity of vascular permeability has been suggested for the coronary system. Whereas arteriolar and capillary segments are tight, plasma proteins pass readily into the interstitial space at venular sites.
Becker, Bernhard F. +8 more
core +1 more source
Advanced Materials Technologies, EarlyView.This review outlines how understanding bone's biology, hierarchical architecture, and mechanical anisotropy informs the design of lattice structures that replicate bone morphology and mechanical behavior. Additive manufacturing enables the fabrication of orthopedic implants that incorporate such structures using a range of engineering materials ...
Stylianos Kechagias +4 more
wiley +1 more source
Unexpected contribution of lymphatic vessels to promotion of distant metastatic tumor spread
Science Advances, 2018 Lymphatic vessels promote organ-to-organ metastasis in addition to mediating tumor cell dissemination from the primary site. Tumor lymphangiogenesis is accompanied by a higher incidence of sentinel lymph node metastasis and shorter overall survival in ...
Qiaoli Ma +11 more
semanticscholar +1 more source
Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems
Advanced Materials Technologies, EarlyView.Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley +1 more source