Results 141 to 150 of about 1,203,096 (351)

Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems

Advanced Materials Technologies, EarlyView.
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley   +1 more source

Lymphatic Vessels Balance Viral Dissemination and Immune Activation following Cutaneous Viral Infection.

Cell Reports, 2017
Lymphatic vessels lie at the interface between peripheral sites of pathogen entry, adaptive immunity, and the systemic host. Though the paradigm is that their open structure allows for passive flow of infectious particles from peripheral tissues to ...
C. P. Loo, Nicholas A. Nelson, Ryan S Lane, Jamie L. Booth, Sofia C Loprinzi Hardin, Archana Thomas, M. Slifka, J. Nolz, A. Lund   +8 more
semanticscholar   +1 more source

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

Visualising lymphatic flow dynamics during complex physical therapy: A photoacoustic imaging study

JPRAS Open
Background: Complex physical therapy (CPT), which combines compression and exercise therapies, is the cornerstone of lymphedema treatment. However, assessing lymphatic flow in living humans is challenging owing to the small size and transparent nature of
Yushi Suzuki, Hiroki Kajita, Anna Oh, Shiho Watanabe, Yoshifumi Takatsume, Nobuaki Imanishi, Hisashi Sakuma, Tetsuya Tsuji, Kazuo Kishi   +8 more
doaj   +1 more source

Characterisation of ovine lymphatic vessels in fresh specimens.

PLoS ONE, 2019
Background and aimThe development and use of experimental models using lymphatic cannulation techniques have been hampered by the lack of high-quality colour imaging of lymphatic vessels in situ.
Hung-Hsun Yen, Christina M Murray, Elizabeth A Washington, Wayne G Kimpton, Helen M S Davies   +4 more
doaj   +1 more source

Commentary: Structural and functional features of central nervous system lymphatic vessels

Frontiers in Neuroscience, 2015
Autism spectrum disorders (ASD) represent an apparent pandemic threat to child development with the current CDC data documenting ASD affecting over 2% of U.S. males of school age ([CDC] Developmental Disabilities Monitoring Network Surveillance Year 2010
J. Bradstreet, M. Ruggiero, S. Pacini
semanticscholar   +1 more source

Sleep Alters the Velocity of Physiological Brain Pulsations in Humans

Advanced Science, EarlyView.
Sleep alters I/CSF oscillatory flow, driven by increased respiratory (29%) and vasomotor pulsation (21%) velocities, while cardiovascular pulsations decreased by (22%). Velocity is quantified using optical flow analysis of MREG data. Spectral power increases alongside these pulsations (spatial correlation, r = 0.35 and r = 0.39, respectively ...
Ahmed Elabasy, Heta Helakari, Tommi Väyrynen, Zalán Rajna, Niko Huotari, Lauri Raitamaa, Ville Isokoski, Matti Järvelä, Mika Kaakinen, Johanna Piispala, Mika Kallio, Vesa Korhonen, Tapio Seppänen, Vesa Kiviniemi   +13 more
wiley   +1 more source

The optimum marker for the detection of lymphatic vessels

Molecular and clinical oncology, 2017
Podoplanin, lymphatic vessel endothelial hyaluronic acid receptor-1, prospero-related homeobox-1 and vascular endothelial growth factor receptor 3 have been demonstrated to have crucial roles in the development of the lymphatic system and ...
Lingling Kong, Nianzhao Yang, Lianghui Shi, Guo-hai Zhao, Wenbin Zhou, Q. Ding, Minghai Wang, Yi-sheng Zhang   +7 more
semanticscholar   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

3D imaging and single-cell analysis reveal cellular heterogeneity of lymphatic valve endothelial cell types

iScience
Summary: Lymphatic vasculature has specialized vessels to support unidirectional interstitial fluid transport and immune surveillance. Although the lymphatic system is a critical actor in skin homeostasis, the spatial organization of the lymphatic ...
Emmanuelle Marchaud, Renaud Morin, Jason S. Iacovoni, Tangra Draia-Nicolau, Aurélie Gomes, Marine Norlund, Pascale Bernes-Lasserre, Jean-Michel Lagarde, Anne-Catherine Prats, Barbara Garmy-Susini, Anne Bouloumie, Anaïs Briot, Florence Tatin   +12 more
doaj   +1 more source