Results 121 to 130 of about 431,164 (300)

3D imaging and single-cell analysis reveal cellular heterogeneity of lymphatic valve endothelial cell types

open access: yesiScience
Summary: Lymphatic vasculature has specialized vessels to support unidirectional interstitial fluid transport and immune surveillance. Although the lymphatic system is a critical actor in skin homeostasis, the spatial organization of the lymphatic ...
Emmanuelle Marchaud   +12 more
doaj   +1 more source

A mouse model of mechanical stress injury to the basal ganglia using thermosensitive PNIPAM hydrogel for intracerebral hemorrhage research

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li   +11 more
wiley   +1 more source

HSC-derived lymphatic endothelial cells stably incorporate into lymphatic vessels.

open access: yes, 2013
a) Six months following transplantation of GFP+, c-kit+/Sca-1+/lin− hematopoietic stem cells, recipient liver was examined for donor-derived lymphatic endothelium, hematopoietic cells, vascular smooth muscle and pericytes.
Philip R. Streeter (375686)   +6 more
core   +1 more source

Establishment and characterization of mouse lymph node fibrosis models

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Schematic illustration of four strategies for establishing mouse lymph node (LN) fibrosis models. The study further compares their fibrotic remodeling patterns and immune alterations. Abstract Background Lymph node (LN) fibrosis occurs in a variety of pathological conditions, including HIV infection, obesity, cancer, and
Yaru Niu   +8 more
wiley   +1 more source

Multimodal Characterization of Glymphatic‐Related Magnetic Resonance Imaging Markers in Huntington's Disease: A Multi‐Cohort Retrospective Study

open access: yesAnnals of Neurology, EarlyView.
Objective To characterize magnetic resonance imaging (MRI)‐based glymphatic surrogates in Huntington's disease (HD) using MRI measures of perivascular diffusivity and structural perivascular alterations across multiple large cohorts. Methods We analyzed 2,731 MRI sessions from 880 participants across 3 large retrospective HD cohorts.
Alexia Solomon   +5 more
wiley   +1 more source

LNT promotes regeneration of collecting lymphatic vessels.

open access: yes, 2016
A) Upper panel: Representative images of ICG lymphangiograms of normal mice (i.e., Cre-Lox mice without DT ablation), mice that had undergone local DT ablation followed by PLND but no LNT (-LNT), and mice that had undergone local DT ablation followed by ...
Babak J. Mehrara (298083)   +8 more
core   +1 more source

The role of lymphatic vessels in the heart

open access: yesPathophysiology, 2010
Although cardiac lymphatic vessels have been described for over three centuries, research progress on the role of cardiac lymphatic vessels in regulating cardiac physiology and their disturbances in the pathogenesis of cardiac disease has progressed very slowly, largely due to technical challenges in developing both animal models and cardiac lymphatic ...
openaire   +2 more sources

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

open access: yesAdvanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi   +6 more
wiley   +1 more source

Percutaneous Lymphatic Contrast-enhanced Ultrasound for Preoperative Localization in Stage 2–3 Lymphedema: A Feasibility Study

open access: yesPlastic and Reconstructive Surgery, Global Open
Background:. Lymphaticovenous anastomosis (LVA) is a crucial surgical method for treating lymphedema by reconstructing lymphatic pathways. The success and efficacy of LVA rely on accurate preoperative localization of functional lymphatic vessels.
Lanjing Wu, MD   +12 more
doaj   +1 more source

A microsurgical method for reconstruction of interrupted lymphatic pathways [PDF]

open access: yes, 1986
Moser, E.   +3 more
core   +1 more source

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