Results 31 to 40 of about 1,011,855 (327)

Subdural haematomas drain into the extracranial lymphatic system through the meningeal lymphatic vessels

Acta Neuropathologica Communications, 2020
Subdural haematomas (SDHs) are characterized by rapidly or gradually accumulated haematomas between the arachnoid and dura mater. The mechanism of haematoma clearance has not been clearly elucidated until now.
Xuanhui Liu, Chuang Gao, Jiangyuan Yuan, Tangtang Xiang, Zhitao Gong, Hongliang Luo, Weiwei Jiang, Yiming Song, Jinhao Huang, W. Quan, Dong Wang, Ye Tian, X. Ge, P. Lei, Jian-ning Zhang, Rongcai Jiang   +15 more
semanticscholar   +1 more source

Mechanical forces in lymphatic vessel development: Focus on transcriptional regulation

Frontiers in Physiology, 2022
The lymphatic system is crucial for the maintenance of interstitial fluid and protein homeostasis. It has important roles in collecting excess plasma and interstitial fluid leaked from blood vessels, lipid absorption and transportation in the digestive ...
Naoto Ujiie, Tsutomu Kume
doaj   +1 more source

S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling

bioRxiv, 2020
During the growth of lymphatic vessels (lymphangiogenesis), lymphatic endothelial cells (LECs) at the growing front sprout by forming filopodia. Those tip cells are not exposed to circulating lymph, as they are not lumenized. In contrast, LECs that trail
Xin Geng, K. Yanagida, R. Akwii, Dongwon Choi, Li-Jun Chen, Y. Ho, B. Cha, Md Riaj Mahamud, Karen Berman de Ruiz, H. Ichise, Hong Chen, Joshua D. Wythe, Constantinos M Mikelis, T. Hla, R. Srinivasan   +14 more
semanticscholar   +1 more source

Potential role of M2 TAMs around lymphatic vessels during lymphatic invasion in papillary thyroid carcinoma

Scientific Reports, 2021
The aim of this study was to examine whether lymphatic invasion in papillary thyroid carcinoma (PTC) occurs when tumour-associated macrophages (TAMs) injure lymphatic vessels together with cancer cells.
Takanobu Kabasawa, Rintaro Ohe, Naing Ye Aung, Yuka Urano, Takumi Kitaoka, Nobuyuki Tamazawa, Aya Utsunomiya, Mitsunori Yamakawa   +7 more
doaj   +1 more source

Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function

Frontiers in Cell and Developmental Biology, 2023
Complex lymphatic anomalies (CLAs) are sporadically occurring diseases caused by the maldevelopment of lymphatic vessels. We and others recently reported that somatic activating mutations in KRAS can cause CLAs.
Lorenzo M. Fernandes, Jeffrey Tresemer, Jing Zhang, Jonathan J. Rios, Jonathan J. Rios, Joshua P. Scallan, Michael T. Dellinger, Michael T. Dellinger   +7 more
doaj   +1 more source

Lymphatic Vessels and Their Surroundings: How Local Physical Factors Affect Lymph Flow

Biology, 2020
Simple Summary Lymphatic vessels are responsible for the drainage of liquids, solutes, and cells from interstitial spaces and serosal cavities. Their task is fundamental in order to avoid fluid accumulation leading to tissue swelling and edema.
E. Solari, C. Marcozzi, D. Negrini, A. Moriondo   +3 more
semanticscholar   +1 more source

Morphometric changes in the blood and lymphatic channels during inflammation [PDF]

BIO Web of Conferences
When the abdominal cavity is inflamed, the lymphatic channel, i.e. the system of lymph vessels and lymph nodes, which play an important role in protecting the body from infections and ensuring proper metabolism, may be affected.
Abreshov Serik, Yessenova Makpal, Yeshmukhanbet Anar, Atanbaeva Gulshat, Demchenko Georgiy   +4 more
doaj   +1 more source

Chronic high-fat diet impairs collecting lymphatic vessel function in mice.

PLoS ONE, 2014
Lymphatic vessels play an essential role in intestinal lipid uptake, and impairment of lymphatic vessel function leads to enhanced adipose tissue accumulation in patients with lymphedema and in genetic mouse models of lymphatic dysfunction.
Katrin S Blum, Sinem Karaman, Steven T Proulx, Alexandra M Ochsenbein, Paola Luciani, Jean-Christophe Leroux, Christian Wolfrum, Michael Detmar   +7 more
doaj   +1 more source

Endothelial-specific depletion of TGF-β signaling affects lymphatic function

Inflammation and Regeneration, 2021
Background Transforming growth factor (TGF)-β is a multifunctional cytokine involved in cell differentiation, cell proliferation, and tissue homeostasis.
Kunpei Fukasawa, Kako Hanada, Kei Ichikawa, Masanori Hirashima, Takahiro Takagi, Susumu Itoh, Testuro Watabe, Fumiko Itoh   +7 more
doaj   +1 more source

Lymphatic Vessels in Tumor Dissemination versus Immunotherapy

Cancer Research, 2020
During the growth of various cancers, primary tumors can escape antitumor immune responses of their host and eventually disseminate into distant organs. Peritumoral lymphatic vessels connect the primary tumor to lymph nodes, facilitating tumor entry into
Kari Vaahtomeri, K. Alitalo
semanticscholar   +1 more source