Results 31 to 40 of about 1,092,661 (368)

Fluorescent Tracers for In Vivo Imaging of Lymphatic Targets

Frontiers in Pharmacology, 2022
The lymphatic system continues to gain importance in a range of conditions, and therefore, imaging of lymphatic vessels is becoming more widespread for research, diagnosis, and treatment. Fluorescent lymphatic imaging offers advantages over other methods
P. S. Russell, P. S. Russell, R. Velivolu, R. Velivolu, V. E. Maldonado Zimbrón, V. E. Maldonado Zimbrón, J. Hong, J. Hong, J. Hong, I. Kavianinia, I. Kavianinia, A. J. R. Hickey, A. J. R. Hickey, J. A. Windsor, J. A. Windsor, A. R. J. Phillips, A. R. J. Phillips, A. R. J. Phillips   +17 more
doaj   +1 more source

Renal lymphatic vessel dynamics

American Journal of Physiology-Renal Physiology, 2020
Similar to other organs, renal lymphatics remove excess fluid, solutes, and macromolecules from the renal interstitium. Given the kidney’s unique role in maintaining body fluid homeostasis, renal lymphatics may be critical in this process. However, little is known regarding the pathways involved in renal lymphatic vessel function, and there are no ...
Elaine L. Shelton, Hai-Chun Yang, Jianyong Zhong, Michele M. Salzman, Valentina Kon   +4 more
openaire   +3 more sources

LED-based photoacoustic imaging for preoperative visualization of lymphatic vessels in patients with secondary limb lymphedema

Photoacoustics, 2023
Lymphedema is the accumulation of protein-rich fluid in the interstitium (i.e., dermal backflow (DBF)). Preoperative imaging of the lymphatic vessels is a prerequisite for lymphovenous bypass surgical planning.
Saskia Van Heumen, Jonas J.M. Riksen, Mithun Kuniyil Ajith Singh, Gijs Van Soest, Dalibor Vasilic   +4 more
doaj   +1 more source

Lymphangiogenesis and angiogenesis during human fetal pancreas development [PDF]

, 2014
Background: The complex endocrine and exocrine functionality of the human pancreas depends on an efficient fluid transport through the blood and the lymphatic vascular systems. The lymphatic vasculature has key roles in the physiology of the pancreas and
Carlotti, Françoise, Chuva de Sousa Lopes, Susana Marina, de Koning, Eelco JP, de Melo Bernardo, Ana, Mummery, Christine L, Roost, Matthias S, van Iperen, Liesbeth   +6 more
core   +1 more source

Optimization and regeneration kinetics of lymphatic-specific photodynamic therapy in the mouse dermis. [PDF]

, 2013
Lymphatic vessels transport fluid, antigens, and immune cells to the lymph nodes to orchestrate adaptive immunity and maintain peripheral tolerance. Lymphangiogenesis has been associated with inflammation, cancer metastasis, autoimmunity, tolerance and ...
Golab, J., Kilarski, W.W., Muchowicz, A., Mężyk-Kopeć, R., Nowak-Sliwinska, P., Swartz, M.A., Wachowska, M.   +6 more
core   +1 more source

T Cell Migration from Inflamed Skin to Draining Lymph Nodes Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1 Interactions. [PDF]

, 2017
T cells are the most abundant cell type found in afferent lymph, but their migration through lymphatic vessels (LVs) remains poorly understood. Performing intravital microscopy in the murine skin, we imaged T cell migration through afferent LVs in vivo ...
Coles, Marc, Debes, Gudrun F., Detmar, Michael, Frei, Thomas, Halin, Cornelia, Hunter, Morgan C., Melero, Ignacio, Proulx, Steven T, Rouzaut, Ana, Russo, Erica, Teijeira, Alvaro   +10 more
core   +3 more sources

Exosome-derived miR-142-5p remodels lymphatic vessels and induces IDO to promote immune privilege in the tumour microenvironment

Cell Death and Differentiation, 2020
Clinical response to immunotherapy is closely associated with the immunosuppressive tumour microenvironment (TME), and influenced by the dynamic interaction between tumour cells and lymphatic endothelial cells (LECs).
Chenfei Zhou, Yanmei Zhang, Ruiming Yan, Lei Huang, A. Mellor, Yang Yang, Xiaojing Chen, Wenfei Wei, Xiangguang Wu, Lan Yu, Luojiao Liang, Dan Zhang, Sha Wu, Wei Wang   +13 more
semanticscholar   +1 more source

Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function

Frontiers in Cell and Developmental Biology, 2023
Complex lymphatic anomalies (CLAs) are sporadically occurring diseases caused by the maldevelopment of lymphatic vessels. We and others recently reported that somatic activating mutations in KRAS can cause CLAs.
Lorenzo M. Fernandes, Jeffrey Tresemer, Jing Zhang, Jonathan J. Rios, Jonathan J. Rios, Joshua P. Scallan, Michael T. Dellinger, Michael T. Dellinger   +7 more
doaj   +1 more source

Three-Dimensional Imaging of Lymphatic System in Lymphedema Legs Using Interstitial Computed Tomography-lymphography [PDF]

, 2017
As a new trial, we used interstitial computed tomography-lymphography (CT-LG) in 10 patients with lower extremity lymphedema (n=20 limbs) at stage 0, 1, 2, or 3 under the International Society of Lymphology (ISL) classification.
Kimata, Yoshihiro, Shinaoka, Akira, Yamada, Kiyoshi   +2 more
core   +1 more source

Chronic high-fat diet impairs collecting lymphatic vessel function in mice.

PLoS ONE, 2014
Lymphatic vessels play an essential role in intestinal lipid uptake, and impairment of lymphatic vessel function leads to enhanced adipose tissue accumulation in patients with lymphedema and in genetic mouse models of lymphatic dysfunction.
Katrin S Blum, Sinem Karaman, Steven T Proulx, Alexandra M Ochsenbein, Paola Luciani, Jean-Christophe Leroux, Christian Wolfrum, Michael Detmar   +7 more
doaj   +1 more source