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Morphometric changes in the blood and lymphatic channels during inflammation [PDF]
BIO Web of ConferencesWhen the abdominal cavity is inflamed, the lymphatic channel, i.e. the system of lymph vessels and lymph nodes, which play an important role in protecting the body from infections and ensuring proper metabolism, may be affected.
Abreshov Serik +4 more
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Scientific Reports, 2021 The aim of this study was to examine whether lymphatic invasion in papillary thyroid carcinoma (PTC) occurs when tumour-associated macrophages (TAMs) injure lymphatic vessels together with cancer cells.
Takanobu Kabasawa +7 more
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Mechanical forces in lymphatic vessel development: Focus on transcriptional regulation
Frontiers in Physiology, 2022 The lymphatic system is crucial for the maintenance of interstitial fluid and protein homeostasis. It has important roles in collecting excess plasma and interstitial fluid leaked from blood vessels, lipid absorption and transportation in the digestive ...
Naoto Ujiie, Tsutomu Kume
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Lymphatic vessels in health and disease [PDF]
WIREs Systems Biology and Medicine, 2012 AbstractThe lymphatic vasculature plays vital roles in tissue fluid balance, immune defense, metabolism, and cancer metastasis. In adults, lymphatic vessel formation and remodeling occur primarily during inflammation, development of the corpus luteum, wound healing, and tumor growth.
Cristina T, Kesler +3 more
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Chronic high-fat diet impairs collecting lymphatic vessel function in mice.
PLoS ONE, 2014 Lymphatic vessels play an essential role in intestinal lipid uptake, and impairment of lymphatic vessel function leads to enhanced adipose tissue accumulation in patients with lymphedema and in genetic mouse models of lymphatic dysfunction.
Katrin S Blum +7 more
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Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function
Frontiers in Cell and Developmental Biology, 2023 Complex lymphatic anomalies (CLAs) are sporadically occurring diseases caused by the maldevelopment of lymphatic vessels. We and others recently reported that somatic activating mutations in KRAS can cause CLAs.
Lorenzo M. Fernandes +7 more
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Renal lymphatic vessel dynamics
American Journal of Physiology-Renal Physiology, 2020 Similar to other organs, renal lymphatics remove excess fluid, solutes, and macromolecules from the renal interstitium. Given the kidney’s unique role in maintaining body fluid homeostasis, renal lymphatics may be critical in this process. However, little is known regarding the pathways involved in renal lymphatic vessel function, and there are no ...
Elaine L. Shelton +4 more
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F1000Research, 2019 The heart contains a complex network of blood and lymphatic vessels. The coronary blood vessels provide the cardiac tissue with oxygen and nutrients and have been the major focus of research for the past few decades.
Xiaolei Liu, Guillermo Oliver
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Endothelial-specific depletion of TGF-β signaling affects lymphatic function
Inflammation and Regeneration, 2021 Background Transforming growth factor (TGF)-β is a multifunctional cytokine involved in cell differentiation, cell proliferation, and tissue homeostasis.
Kunpei Fukasawa +7 more
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Detection of Lymphatic Vessels in the Superficial Fascia of the Abdomen
Life, 2023 Recently, the superficial fascia has been recognized as a specific anatomical structure between the two adipose layers—the superficial adipose tissue (SAT) and the deep adipose tissue (DAT).
Giovanna Albertin +9 more
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