Results 51 to 60 of about 208,667 (379)

Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain

eLife, 2022
The discovery of meningeal lymphatic vessels that drain the CNS has prompted new insights into how immune responses develop in the brain. In this study, we examined how T cell responses against CNS-derived antigen develop in the context of infection.
Michael A Kovacs, Maureen N Cowan, Isaac W Babcock, Lydia A Sibley, Katherine Still, Samantha J Batista, Sydney A Labuzan, Ish Sethi, Tajie H Harris   +8 more
doaj   +1 more source

A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo [PDF]

, 2012
In vivo imaging has revolutionized understanding of the spatiotemporal complexity that subserves the generation of successful effector and regulatory immune responses.
Andrea J. White, Butcher, Cardillo, Carragher, Catherine M. Rush, Celli, de Boer, Eric J. Jenkinson, Farr, Fulmer, Gianluca Grassia, Girard, Graham Anderson, Gunn, Hillebrands, Huang, Iain B. McInnes, Itano, James M. Brewer, Karen J. Bryson, Kono, Lane, Leishman, Luther, McNagny, Millington, Pasquale Maffia, Paul Garside, Proudman, Robert A. Benson, Schneider, Smith, Stutzmann, Sumen, Tammela, Tomei, Vivienne B. Gibson, White, Worbs, Yoshida, Zinselmeyer   +40 more
core   +1 more source

Perspective: Pathological transdifferentiation—a novel therapeutic target for cardiovascular diseases and chronic inflammation

Frontiers in Cardiovascular Medicine
Pathological transdifferentiation, where differentiated cells aberrantly transform into other cell types that exacerbate disease rather than promote healing, represents a novel and significant concept.
William Y. Yang, Mohammed Ben Issa, Fatma Saaoud, Keman Xu, Ying Shao, Yifan Lu, Waleska Dornas, Ramon Cueto, Xiaohua Jiang, Xiaohua Jiang, Hong Wang, Xiaofeng Yang, Xiaofeng Yang   +12 more
doaj   +1 more source

Dermal Lymphatic Capillaries Do Not Obey Murray's Law

Frontiers in Cardiovascular Medicine, 2022
Lymphatic vessels serve as a major conduit for the transport of interstitial fluid, immune cells, lipids and drugs. Therefore, increased knowledge about their development and function is relevant to clinical issues ranging from chronic inflammation and ...
Anne M. Talkington, Anne M. Talkington, Reema B. Davis, Nicholas C. Datto, Emma R. Goodwin, Laura A. Miller, Kathleen M. Caron   +6 more
doaj   +1 more source

Renal Lymphatics: Anatomy, Physiology, and Clinical Implications

Frontiers in Physiology, 2019
Renal lymphatics are abundant in the cortex of the normal kidney but have been largely neglected in discussions around renal diseases. They originate in the substance of the renal lobule as blind-ended initial capillaries, and can either follow the main ...
P. Russell, Jiwon Hong, J. Windsor, M. Itkin, A. Phillips   +4 more
semanticscholar   +1 more source

THE LYMPHATICS IN LEPROSY. [PDF]

The Lancet, 1879
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openaire   +3 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Impact of Lymphangiogenesis on Cardiac Remodeling After Ischemia and Reperfusion Injury

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Lymphatic vessels interconnect with blood vessels to form an elaborate system that aids in the control of tissue pressure and edema formation. Although the lymphatic system has been known to exist in a heart, little is known about the role the
Yuuki Shimizu, Rohini Polavarapu, Kattri‐Liis Eskla, Yvanna Pantner, Chad K. Nicholson, Masakazu Ishii, Daniel Brunnhoelzl, Rohit Mauria, Ahsan Husain, Nawazish Naqvi, Toyoaki Murohara, John W. Calvert   +11 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

The Cardiac Lymphatics

The Annals of Thoracic Surgery, 1973
Abstract The cardiac lymphatic system is well developed. Investigations related to the lymphatics of the heart are recorded as early as the seventeenth century, and with improved techniques, many studies have produced new knowledge of the system during this century. Controversy remains, however, regarding the presence of lymphatics in certain areas of
Edward F. Parker, R. Randolph Bradham
openaire   +3 more sources