Results 261 to 270 of about 164,625 (307)
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Hematology, 2002
AbstractThis is a comprehensive overview on the most recent developments in diagnosis and treatment of acute lymphoblastic leukemia (ALL).Dr. Dieter Hoelzer and colleagues give an overview of current chemotherapy approaches, prognostic factors, risk stratification, and new treatment options such as tyrosine kinase inhibitors and monoclonal antibodies ...
Dieter, Hoelzer +7 more
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AbstractThis is a comprehensive overview on the most recent developments in diagnosis and treatment of acute lymphoblastic leukemia (ALL).Dr. Dieter Hoelzer and colleagues give an overview of current chemotherapy approaches, prognostic factors, risk stratification, and new treatment options such as tyrosine kinase inhibitors and monoclonal antibodies ...
Dieter, Hoelzer +7 more
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Lymphoblastic Lymphoma with the Phenotype of Common Acute Lymphoblastic Leukemia
American Journal of Clinical Pathology, 1983Immunologic phenotyping of lymphoblastic lymphomas has shown that most of these are tumors of T-cell origin. In this report, we describe two patients with biopsy-proven lymphoblastic lymphoma whose tumors had no T-cell markers when tested by immunoperoxidase with a large panel of monoclonal antibodies.
M J, Borowitz, B P, Croker, R S, Metzgar
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Best Practice & Research Clinical Haematology, 2001
Precursor B-ALL (BCP-ALL) is associated with a good outcome in children. Cytogenetics is one of the gold standards for risk stratification for treatment that has contributed to improved survival. Although in T-ALL genetic analysis has not been used to guide therapy, it has contributed significantly to the understanding of the biology.
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Precursor B-ALL (BCP-ALL) is associated with a good outcome in children. Cytogenetics is one of the gold standards for risk stratification for treatment that has contributed to improved survival. Although in T-ALL genetic analysis has not been used to guide therapy, it has contributed significantly to the understanding of the biology.
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Lancet, The, 2008
Acute lymphoblastic leukaemia, a malignant disorder of lymphoid progenitor cells, affects both children and adults, with peak prevalence between the ages of 2 and 5 years. Steady progress in development of effective treatments has led to a cure rate of more than 80% in children, creating opportunities for innovative approaches that would preserve past ...
Les Robison, Thomas Look, Ching-Hon Pui
exaly +3 more sources
Acute lymphoblastic leukaemia, a malignant disorder of lymphoid progenitor cells, affects both children and adults, with peak prevalence between the ages of 2 and 5 years. Steady progress in development of effective treatments has led to a cure rate of more than 80% in children, creating opportunities for innovative approaches that would preserve past ...
Les Robison, Thomas Look, Ching-Hon Pui
exaly +3 more sources
Pediatric Clinics of North America, 1997
Advances in the molecular and immunologic characterization of leukemic cells have greatly aided the diagnosis and risk assignment of ALL, as well as the monitoring of bone marrow samples for minimal residual disease. Currently, 75% of childhood cases have biologically and therapeutically relevant genetic abnormalities.
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Advances in the molecular and immunologic characterization of leukemic cells have greatly aided the diagnosis and risk assignment of ALL, as well as the monitoring of bone marrow samples for minimal residual disease. Currently, 75% of childhood cases have biologically and therapeutically relevant genetic abnormalities.
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Lymphoblastic lymphoma in adults
Current Hematologic Malignancy Reports, 1996Understanding of the pathogenesis and biology of precursor T-cell and B-cell neoplasms has advanced significantly with the description of gene expression profiling studies, especially in T-cell disease. These studies have demonstrated leukemic arrest at various stages of thymocyte maturation, characterized by gene expression signatures with prognostic ...
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Journal of Wound Care, 1997
This study describes the management of a baby with acute lymphoblastic leukaemia, who developed a lesion in the natal cleft
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This study describes the management of a baby with acute lymphoblastic leukaemia, who developed a lesion in the natal cleft
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The Cancer Journal, 2012
Adult lymphoblastic lymphoma (LBL) is an aggressive form of non-Hodgkin lymphoma occurring in predominantly adolescent and young adult men. Lymphoblastic lymphoma is rare, accounting for 1% to 2% of all non-Hodgkin lymphomas and is of T-cell phenotype in 90% of cases.
Craig A, Portell, John W, Sweetenham
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Adult lymphoblastic lymphoma (LBL) is an aggressive form of non-Hodgkin lymphoma occurring in predominantly adolescent and young adult men. Lymphoblastic lymphoma is rare, accounting for 1% to 2% of all non-Hodgkin lymphomas and is of T-cell phenotype in 90% of cases.
Craig A, Portell, John W, Sweetenham
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2007
Acute lymphoblastic leukemia (ALL) comprises a heterogeneous group of disorders which originate from various important genetic lesions in B and T progenitor cells, including mutations that lead to stage-specific developmental arrest and those that impart the capacity for unlimited self-renewal, resulting in clonal expansion of immature progenitor cells
Biondi A., Scrideli C. A., Cazzaniga G.
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Acute lymphoblastic leukemia (ALL) comprises a heterogeneous group of disorders which originate from various important genetic lesions in B and T progenitor cells, including mutations that lead to stage-specific developmental arrest and those that impart the capacity for unlimited self-renewal, resulting in clonal expansion of immature progenitor cells
Biondi A., Scrideli C. A., Cazzaniga G.
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2011
Cytogenetics plays an important role in the diagnosis of acute lymphoblastic leukaemia (ALL), particularly in relation to the association of specific chromosomal abnormalities with outcome. The karyotype at diagnosis is used in the risk stratification of patients for treatment within trial-based protocols. Chromosomal analysis of the leukaemic cells of
Claire, Schwab, Christine J, Harrison
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Cytogenetics plays an important role in the diagnosis of acute lymphoblastic leukaemia (ALL), particularly in relation to the association of specific chromosomal abnormalities with outcome. The karyotype at diagnosis is used in the risk stratification of patients for treatment within trial-based protocols. Chromosomal analysis of the leukaemic cells of
Claire, Schwab, Christine J, Harrison
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