Uptake of systematic reviews and meta-analyses based on individual participant data in clinical practice guidelines: descriptive study. [PDF]
, 2015 To establish the extent to which systematic reviews and meta-analyses of individual participant data (IPD) are being used to inform the recommendations included in published clinical ...
Cochrane IPD Meta-analysis Methods Group, . +6 more
core +2 more sources
Dupilumab and Systemic Hematologic Malignancies: Case Series and Literature Review
JEADV Clinical Practice, EarlyView.ABSTRACT Background Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting 15%–20% of children and 3%–10% of adults. An increased risk of systemic lymphomas – but not leukemias – has been reported in patients with AD. Dupilumab, a monoclonal IgG4 antibody targeting IL‐4 and IL‐13 signaling, is approved for moderate‐to‐severe AD and is ...
Nello Tommasino +3 more
wiley +1 more source
Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies. [PDF]
, 2018 Human cells express thousands of different surface proteins that can be used for cell classification, or to distinguish healthy and disease conditions.
Adams, Jarrett J +12 more
core +1 more source
Role of allogeneic hematopoietic stem cell transplantation in patients with high-risk T-cell lymphoblastic leukaemia/lymphoma: An analysis of clinical outcomes [PDF]
, 2023 Lan Deng +7 more
openalex +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu +5 more
wiley +1 more source
Gastrointestinal B-lymphoblastic lymphoma in a dog: a case report
Veterinární Medicína, 2018 A four-year-old Bullmastiff weighing 44 kg was presented with a 14-day history of weight loss, vomiting and diarrhoea. Abdominal ultrasonography showed the presence of abdominal lymphadenopathy and thickening of the wall of the descending colon ...
P. Borska +5 more
doaj +1 more source
Med Research, EarlyView.Using data from the Global Burden of Disease Study 2021, we systematically assessed leukemia prevalence and disability‐adjusted life years (DALYs) across 204 countries and territories from 1990 to 2021, stratified by subtype, demographics, and risk factors.
Yuping Wu +8 more
wiley +1 more source
Precursor B Lymphoblastic Lymphoma Involving the Stomach
Case Reports in Gastrointestinal Medicine, 2013 Precursor B lymphoblastic lymphoma is a high-grade neoplasm arising from precursor lymphocytes of B-cell lineage. Extranodal sites such as the skin and bone are often involved, but gastrointestinal lesions of this disease are rarely encountered.
Masaya Iwamuro +4 more
doaj +1 more source
MicroRNAs in B cell development and malignancy [PDF]
, 2012 MicroRNAs are small RNA molecules that regulate gene expression and play critical roles in B cell development and malignancy. miRNA expression is important globally, as B cell specific knockouts of Dicer show profound defects in B cell development; and ...
Fernando, Thilini R. +2 more
core +4 more sources
Reciprocal ATP5L–KMT2A gene fusion in a paediatric B lymphoblastic leukaemia/lymphoma (B‐ALL) patient [PDF]
, 2020 Catherine K. Gestrich +4 more
openalex +1 more source