Results 111 to 120 of about 491,626 (323)

Cranial nerve palsy in childhood acute lymphoblastic leukemia and non-Hodgkin's lymphoma [PDF]

open access: bronze, 1991
Lewis C. Ingram   +6 more
openalex   +1 more source

Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development

open access: yesLeukemia, 2015
The JAK-STAT pathway has a substantial role in lymphoid precursor cell proliferation, survival and differentiation. Nonetheless, the contribution of JAK2 to T-cell lymphoblastic lymphoma (T-LBL) development remains poorly understood.
A. Roncero   +15 more
semanticscholar   +1 more source

From Genomic and Epigenomic Maps to Medicines in Adult T‐Cell Leukemia/Lymphoma

open access: yesCancer Science, EarlyView.
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive and refractory hematologic malignancy that is caused by human T‐cell leukemia virus type‐1 (HTLV‐1) retrovirus. ATL results from a combination of viral latency and the accumulation of abnormalities throughout the genome, epigenome, transcriptome, and signaling pathways.
Kako Suzuki, Makoto Yamagishi
wiley   +1 more source

Chloroma of perianal region masquerading as perianal abscess

open access: yesIndian Journal of Dermatology, 2013
Chloroma, also called granulocytic sarcoma (GS) or Myeloid Sarcoma, is a rare malignant extra-medullary neoplasm of myeloid precursor cells. It is usually associated with myeloproliferative disorders but its appearance may precede the onset of leukaemia.
Rajeev Sen   +5 more
doaj   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

open access: yesEuropean Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

Dasatinib Produces Lengthy Remissions of Extramedullary Leukemia: A Retrospective Observational Study

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Since 2004, patients receiving imatinib with relapse in non‐marrow sites were given dasatinib to preserve control of leukemic marrow. Remissions in CNS and other organs began to be reported and are continuously observed to present. With resistance to one BCR::ABL1 tyrosine kinase inhibitor and sensitivity to a dual BCR::ABL1/SRC inhibitor ...
I. Cunningham   +4 more
wiley   +1 more source

Successful Outcomes of Newly Diagnosed T Lymphoblastic Lymphoma: Results From Children’s Oncology Group AALL0434

open access: green, 2020
Robert J. Hayashi   +17 more
openalex   +2 more sources

Precursor B-Cell Lymphoblastic Lymphoma [PDF]

open access: bronze, 2001
Anirban Maitra   +4 more
openalex   +1 more source

Emerging Techniques in Minimally Invasive Surgery in Hematologic Malignancies

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Hematologic malignancies represent the most common cancers in children. While the mainstays of treatment are chemotherapy and potentially hematopoietic stem cell transplant, minimally invasive surgery (MIS) has a role in the diagnosis and management of complications related both to disease and therapy as well as common pediatric surgical ...
Alejandro Chara   +3 more
wiley   +1 more source

Restricted Expression of the Constant Region 1 of T‐Cell Receptor β by Flow Cytometry Facilitates Detection of T‐Cell Neoplasms With High Specificity but Moderate Predictive Value

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Objectives To determine the diagnostic value of disclosing monotypic T‐cell populations by expression analysis of the constant region 1 of T‐cell receptor β (TRBC1) by flow cytometry, for the detection of T‐cell neoplasms, in a routine hematopathology practice setting.
Nilofar Rajabian   +4 more
wiley   +1 more source

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