Results 131 to 140 of about 63,047 (307)

T-Lineage Lymphoblastic Lymphoma and Leukemia—a MASSive Problem

open access: yes, 2010
T cell precursor malignancies may present as T-lymphoblastic lymphoma (T-LBL) with marked enlargement of lymph nodes or acute T-lymphoblastic leukemia (T-ALL) with little lymph node enlargement. In this issue of Cancer Cell, Feng et al.
Mullighan, Charles G.   +1 more
core   +1 more source

A Personalised Vaccination Program Based on Immune Reconstitution in Paediatric Cancer Survivors

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aims Paediatric cancer survivors often experience treatment‐induced immunosuppression, requiring post‐treatment revaccination. However, immune recovery timelines vary, and current revaccination guidelines, largely based on data of varied quality derived from studies on acute‐lymphoblastic‐leukaemia (ALL), may not be applicable across all ...
Menucha Jurkowicz   +17 more
wiley   +1 more source

Central nervous system involvement and relapse in adult acute lymphoblastic leukaemia—a population‐based analysis in 2007–2022

open access: yesBritish Journal of Haematology, EarlyView.
Summary Central nervous system (CNS) involvement and relapse remains a clinical challenge in the management of acute lymphoblastic leukaemia (ALL), and studies among adult ALL patients are scarce. We identified all adult ALL patients in Sweden between 2007 and 2022 (n = 838) from the population‐based ALL register and evaluated factors associated with ...
Erik Boberg   +7 more
wiley   +1 more source

Emperipolesis in a Case of Adult T Cell Lymphoblastic Lymphoma (Mediastinal type)-Detected at FNAC and Imprint Cytology

open access: yesOnline Journal of Health & Allied Sciences, 2011
Emperipolesis is a condition in which viable hematopoetic cells are seen intact in the cytoplasm of host cell without damage. This phenomenon is seen in many physiologic and pathologic conditions, its presence in Rosai Dorfman disease (RDD) is ...
Amita K   +3 more
doaj  

Case report: Preventive infusion of donor-derived CD7 chimeric antigen receptor T cells after allogeneic hematopoietic stem cell transplantation

open access: yesFrontiers in Immunology
Chimeric antigen receptor T cells (CAR T) targeting CD7 for T-cell acute lymphoblastic leukemia/lymphoma (T-ALL/LBL) showed promising efficacy and safety in some clinical trials.
Ying Jiang   +7 more
doaj   +1 more source

Human immunodeficiency virus-associated precursor T-lymphoblastic leukemia/lymphoblastic lymphoma: report of a case and review of the literature

open access: yes, 2009
We describe a case of human immunodeficiency virus-associated T-lymphoblastic leukemia/lymphoblastic lymphoma in a 43-year-old Italian man with a history of human immunodeficiency virus infection lasting 9 years.
Lorenzon D   +11 more
core   +1 more source

Blocking SETD2 Enhances the Therapeutic Efficiency of Menin Inhibitor in MLL‐Fusion Leukemia

open access: yesCancer Science, EarlyView.
Combined SETD2 and menin inhibitors make synergistic effects against MLL‐fusion leukemia; the combination therapy reduces the expression of target genes through blocking transcription elongation and initiation. ABSTRACT During transcriptional elongation, the histone methyltransferase SETD2 binds to RNA polymerase II and deposits trimethylation marks at
Anpei Li   +10 more
wiley   +1 more source

Mandible infiltration as a clinical signal of extramedullary B-cell acute lymphoblastic leukemia/lymphoma in a child: Report of a rare case

open access: yesOral Oncology Reports
B-cell lymphoblastic leukemia/lymphoma (B-ALL/LBL) is a type of malignancy involving uncontrolled proliferation of B-precursor lymphoid cells. This case report delineates B-cell lymphoblastic leukemia/lymphoma (B-ALL/LBL) manifesting in the mandible and ...
Paulo Victor Mendes Penafort   +7 more
doaj   +1 more source

Superficial Ewing Sarcoma of the Rectum: A Case Report and the Utility of Molecular Diagnostics

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Ewing sarcoma is an undifferentiated small round cell sarcoma that most commonly presents as a malignant bone tumor in pediatric and young adult patients. The diagnosis is typically confirmed by molecular genetic identification of a fusion protein, most commonly involving members of the FET and ETS gene families.
Jessica L. Muldoon   +3 more
wiley   +1 more source

Non Hodgkin’s lymphoma seven years following remission of acute lymphoblastic leukemia

open access: yes, 2004
The authors describe a case of extramedullary relapse in lymph node presenting as lymphoblastic lymphoma seven years following remission of acute lymphoblastic leukemia.
Padmanjali, K.   +5 more
core   +1 more source

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