Results 151 to 160 of about 63,047 (307)

Parâmetros de funcionalidade de células mononucleares, de estresse oxidativo, proteínas de fase aguda e estado nutricional de indivíduos portadores de neoplasias hematológicas antes do tratamento quimioterápico [PDF]

open access: yes, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Nutrição, Florianópolis, 2013.Neoplasias hematológicas são cânceres que se iniciam em tecidos produtores de células sanguíneas e no
Camargo, Carolina de Quadros
core  

Plasma Elastase Screening in Hematological Disease Reveals Its Potential as a Diagnostic and Prognostic Biomarker in Hematological Malignancies

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala   +14 more
wiley   +1 more source

BCL‐2 and MCL1 co‐inhibition enhances glucocorticoid therapy in preclinical models of infant KMT2A‐rearranged acute lymphoblastic leukaemia

open access: yes
British Journal of Haematology, EarlyView.
Mawar Karsa   +19 more
wiley   +1 more source

Clonal Hematopoiesis and CAR T Cell Therapy: From Biological Crosstalk to Clinical Implications

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Clonal hematopoiesis (CH) is increasingly recognized as a significant biological phenomenon in aging and cancer, marked by the expansion of hematopoietic stem and progenitor cells harboring somatic mutations in genes associated with myeloid neoplasms.
Wei Du   +4 more
wiley   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra   +5 more
wiley   +1 more source

Oral Mucositis in Oncopediatric Patients: MTX and MMP‐1, MMP‐8, MMP‐13 Gene Polymorphisms

open access: yesOral Diseases, EarlyView.
ABSTRACT Background This study investigates the association between single‐nucleotide polymorphisms (SNPs) in the MMP‐1, MMP‐8, and MMP‐13 genes and the risk of oral mucositis development in paediatric patients with leukaemia and lymphoma who are undergoing methotrexate (MTX) treatment.
Nicole Januário Ribeiro   +6 more
wiley   +1 more source

Challenges of Dengue in Hematological Disease Patients: Descriptive Analysis From the DANGO Registry During the 2023–2024 Outbreak in Argentina

open access: yesTransplant Infectious Disease, EarlyView.
During the 2023–2024 Argentine dengue outbreak, 33 patients with hematological disease showed high complication rates, frequent hospitalization (64%), severe thrombocytopenia (90%), and 6% dengue‐attributable mortality. Transfusion‐associated cases were documented.
Gustavo Adolfo Méndez   +16 more
wiley   +1 more source

Lymphoma Prevalence Patterns in Uganda, 1969-2006

open access: yesMiddle East Journal of Cancer, 2013
Background: Lymphomas are a complex group of malignancies that requireadvanced technology for proper classification. Unfortunately Uganda, as with numerousother Sub-Saharan African countries, lacks these resources.
Adriane Kamulegeya, Louis Muwazi
doaj  

Impaired hematopoiesis affects apheresis and CAR T‐cell product composition and treatment response

open access: yesTransfusion, EarlyView.
Abstract Background Chimeric antigen receptor (CAR) T‐cell therapy has transformed the treatment of hematologic malignancies, but its success depends on obtaining sufficient CD3+ T‐cell yields during leukapheresis. This can be difficult in heavily pretreated patients, who often show leukopenia and reduced T‐cell fitness.
Hanna Kuhn   +14 more
wiley   +1 more source

Clinical application of a modified platelet desialylation test for mechanistic characterization of platelet transfusion refractoriness

open access: yesTransfusion, EarlyView.
Abstract Background Platelet transfusion refractoriness (PTR) is a major challenge in transfusion medicine and may result from both immune and non‐immune mechanisms. Although alloantibodies are well‐established contributors, Fc‐independent pathways such as platelet desialylation have emerged as alternative mechanisms of clearance.
Karen Ziza   +11 more
wiley   +1 more source

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