Results 131 to 140 of about 81,713 (355)
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
International Journal of Cancer, EarlyView.Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
Chemotactic Cues for NOTCH1-Dependent Leukemia [PDF]
, 2018 The NOTCH signaling pathway is a conserved signaling cascade that regulates many aspects of development and homeostasis in multiple organ systems.
Amadori, Alberto +3 more
core +1 more source
JPGN Reports, EarlyView.Abstract Constitutional mismatch repair deficiency (CMMRD) is a rare hereditary cancer syndrome resulting from biallelic mutations in DNA mismatch repair (MMR) genes that lead to early‐onset cancers in children, including lymphoma and colorectal cancer (CRC).
Chloe J. Cohan +3 more
wiley +1 more source
Breastfeeding patterns and risk of childhood acute lymphoblastic leukaemia. [PDF]
, 2005 The risk of childhood acute lymphoblastic leukaemia (ALL) was investigated in relation to breastfeeding patterns in the Northern California Childhood Leukaemia Study.
Block, G +6 more
core +2 more sources
ChemistryOpen, EarlyView.Quinazoline represents an important class of heterocycles with diverse medicinal and pharmacological significance. This review systematically examines scholarly efforts toward understanding different synthetic pathways emphasizing the role of metal and non‐metal catalysts including some miscellaneous reagents employed in the synthesis of quinazoline ...
Neha Manhas +4 more
wiley +1 more source
Chloroma of perianal region masquerading as perianal abscess
Indian Journal of Dermatology, 2013 Chloroma, also called granulocytic sarcoma (GS) or Myeloid Sarcoma, is a rare malignant extra-medullary neoplasm of myeloid precursor cells. It is usually associated with myeloproliferative disorders but its appearance may precede the onset of leukaemia.
Rajeev Sen +5 more
doaj +1 more source
Nanomedicine for the Treatment of Non-Hodgkin Lymphoma [PDF]
, 2019 Non-Hodgkin lymphoma, or NHL, is the predominant category of lymphoma. NHL is a type of lymphoid hematopoietic malignancy which approximately 70,000 Americans are diagnosed with annually, with the number of diagnoses growing annually.
Gandhi, B.Pharm, Tanvi
core +1 more source
IMMUNOLOGIC MARKERS AND MORPHOLOGY IN CHILDHOOD LYMPHOBLASTIC LYMPHOMA [PDF]
, 1978 F Zintl, W Plenert, D Stiller
openalex +1 more source
Identification of PPFIA3 as a Potential Prognostic and Immune Biomarker Through Pan‐Cancer Analysis
Organ Medicine, EarlyView.This study reveals a significant increase in the expression of PPFIA3 across various cancers, which is associated with poor prognosis. Notably, in patients receiving anti‐PD‐L1 treatment, high PPFIA3 expression is closely linked to improved survival rates and favorable prognosis, suggesting its potential as a predictive factor for immune checkpoint ...
Xianghong Wang +4 more
wiley +1 more source
Methotrexate-induced chemical meningitis in patients with acute lymphoblastic leukemia/lymphoma
Annals of Indian Academy of Neurology, 2015 Background: Intrathecal methotrexate (ITMTX) is an important component in the treatment as well as prophylaxis of leukemia/lymphoma. ITMTX can cause chemical meningitis characterized by vomiting, headache, and fever lasting 2-5 days with spontaneous ...
Linu A Jacob +5 more
doaj +1 more source