Results 1 to 10 of about 597,213 (313)
Early Interferon-γ Production in Human Lymphocyte Subsets in Response to Nontyphoidal Salmonella Demonstrates Inherent Capacity in Innate Cells [PDF]
, 2010 Background Nontyphoidal Salmonellae frequently cause life-threatening bacteremia in sub-Saharan Africa. Young children and HIV-infected adults are particularly susceptible.
Anna E. Seeley +5 more
core +14 more sources
Frontiers in Immunology, 2023 IntroductionMHC class II molecules are essential for appropriate immune responses against pathogens but are also implicated in pathological responses in autoimmune diseases and transplant rejection.
Camilla Wibrand +12 more
doaj +1 more source
Neutrophil-to-Lymphocyte, Platelet-to-Lymphocyte and Monocyte-to-Lymphocyte Ratio in Bipolar Disorder [PDF]
Brain Sciences, 2021 Background: Several inflammatory hypotheses have been suggested to explain the etiopathogenesis of bipolar disorder (BD) and its different phases. Neutrophil-to-lymphocyte (NLR), platelet-to-lymphocyte (PLR), and monocyte-to-lymphocyte (MLR) ratios have been proposed as potential peripheral biomarkers of mood episodes.
Antimo Natale +9 more
openaire +6 more sources
The Oncologist, 1999 Abstract Mechanisms in Hematology is a book with an accompanying interactive CD-ROM designed to assemble basic concepts that underlie clinical understanding and progress. It is presented as a concise text with a series of diagrams that distill diffuse information into a compact form.
Esther D. Israels, Lyonel G. Israels and
openaire +3 more sources
Generation of High Quality Memory B Cells
Frontiers in Immunology, 2022 Protection against pathogen re-infection is mediated, in large part, by two humoral cellular compartments, namely, long-lived plasma cells and memory B cells.
Takeshi Inoue +4 more
doaj +1 more source
Assessing the impact of an antigen-specific antibody response on atherosclerosis development in mice
STAR Protocols, 2023 Summary: The antibody immune response plays a critical role in atherosclerosis. Here, we present a protocol for assessing the impact of an antigen-specific germinal center antibody response on atherosclerosis development, using a pro-atherogenic mouse ...
Alberto Del Monte-Monge +3 more
doaj +1 more source
Cell polarity regulators, multifunctional organizers of lymphocyte activation and function
Biomedical Journal, 2022 Cell polarity regulators are ubiquitous, evolutionary conserved multifunctional proteins. They contain a variety of protein–protein interaction domains endowing them the capacity to interact with cytoskeleton structures, membrane components and multiple ...
Marta Mastrogiovanni +2 more
doaj +1 more source
Antigen presentation by B cells enables epitope spreading across an MHC barrier
Nature Communications, 2023 Circumstantial evidence suggests that B cells may instruct T cells to break tolerance. Here, to test this hypothesis, we used a murine model in which a single B cell clone precipitates an autoreactive response resembling systemic lupus erythematosus (SLE)
Cecilia Fahlquist-Hagert +22 more
doaj +1 more source
Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5
Cell Reports, 2020 Summary: The germinal center (GC) response is critical for generating high-affinity humoral immunity and immunological memory, which forms the basis of successful immunization. Control of the GC response is thought to require follicular regulatory T (Tfr)
Ine Vanderleyden +8 more
doaj +1 more source
Lymphocytes in atherosclerosis [PDF]
Clinica Chimica Acta, 2012 It is well established that atherosclerosis is caused by an inflammatory process in the arterial intima. However, it is only in recent years that it has become clear that this inflammation is modulated by immune responses against plaque antigens. These antigens are primarily believed to be modified self-antigens such as oxidized LDL.
Wigren, Maria +2 more
openaire +5 more sources