Results 1 to 10 of about 957,946 (242)

B cell MHC haplotype affects follicular inclusion, germinal center participation and plasma cell differentiation in a mouse model of lupus

open access: yesFrontiers in Immunology, 2023
IntroductionMHC class II molecules are essential for appropriate immune responses against pathogens but are also implicated in pathological responses in autoimmune diseases and transplant rejection.
Camilla Wibrand   +12 more
doaj   +1 more source

Early Interferon-γ Production in Human Lymphocyte Subsets in Response to Nontyphoidal Salmonella Demonstrates Inherent Capacity in Innate Cells [PDF]

open access: yes, 2010
Background Nontyphoidal Salmonellae frequently cause life-threatening bacteremia in sub-Saharan Africa. Young children and HIV-infected adults are particularly susceptible.
Anna E. Seeley   +5 more
core   +14 more sources

Lymphocytes [PDF]

open access: yesThe Oncologist, 1999
Abstract Mechanisms in Hematology is a book with an accompanying interactive CD-ROM designed to assemble basic concepts that underlie clinical understanding and progress. It is presented as a concise text with a series of diagrams that distill diffuse information into a compact form.
Esther D. Israels, Lyonel G. Israels and
openaire   +3 more sources

Neutrophil-to-Lymphocyte, Platelet-to-Lymphocyte and Monocyte-to-Lymphocyte Ratio in Bipolar Disorder [PDF]

open access: yesBrain Sciences, 2021
Background: Several inflammatory hypotheses have been suggested to explain the etiopathogenesis of bipolar disorder (BD) and its different phases. Neutrophil-to-lymphocyte (NLR), platelet-to-lymphocyte (PLR), and monocyte-to-lymphocyte (MLR) ratios have been proposed as potential peripheral biomarkers of mood episodes.
Antimo Natale   +9 more
openaire   +5 more sources

Generation of High Quality Memory B Cells

open access: yesFrontiers in Immunology, 2022
Protection against pathogen re-infection is mediated, in large part, by two humoral cellular compartments, namely, long-lived plasma cells and memory B cells.
Takeshi Inoue   +4 more
doaj   +1 more source

Antigen presentation by B cells enables epitope spreading across an MHC barrier

open access: yesNature Communications, 2023
Circumstantial evidence suggests that B cells may instruct T cells to break tolerance. Here, to test this hypothesis, we used a murine model in which a single B cell clone precipitates an autoreactive response resembling systemic lupus erythematosus (SLE)
Cecilia Fahlquist-Hagert   +22 more
doaj   +1 more source

Lymphocytes in atherosclerosis [PDF]

open access: yesClinica Chimica Acta, 2012
It is well established that atherosclerosis is caused by an inflammatory process in the arterial intima. However, it is only in recent years that it has become clear that this inflammation is modulated by immune responses against plaque antigens. These antigens are primarily believed to be modified self-antigens such as oxidized LDL.
Wigren, Maria   +2 more
openaire   +5 more sources

Antigen-specific electrophoretic cell separation for immunological investigations [PDF]

open access: yes, 1989
Preincubation of human blood lymphocytes with cell surface antigen specific antibodies under non-capping conditions reduces the electrophoretic mobility of the corresponding lymphocyte subpopulation.
Hannig, K.   +2 more
core   +1 more source

Adenomatous Polyposis Coli Defines Treg Differentiation and Anti-inflammatory Function through Microtubule-Mediated NFAT Localization

open access: yesCell Reports, 2017
Adenomatous polyposis coli (APC) is a polarity regulator and tumor suppressor associated with familial adenomatous polyposis and colorectal cancer development.
Sonia Agüera-González   +9 more
doaj   +1 more source

Dynamic 3D Locus Organization and Its Drivers Underpin Immunoglobulin Recombination

open access: yesFrontiers in Immunology, 2021
A functional adaptive immune system must generate enormously diverse antigen receptor (AgR) repertoires from a limited number of AgR genes, using a common mechanism, V(D)J recombination.
Carolyn H. Rogers   +2 more
doaj   +1 more source

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