C-reactive protein to lymphocyte ratio is associated with asthma: a cross-sectional study
Background C-reactive protein to lymphocyte ratio (CLR), a newly identified inflammatory biomarker, has been associated with various inflammatory conditions.
Yun Guo, Wei Zhou
doaj +1 more source
The Relationship of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio with High Sensitivity C-Reactive Protein Level in Hemodialysis Patients [PDF]
Background: Hemodialysis (HD) is the treatment of end-stage renal disease (ESRD), which leads to increased inflammation and mortality. This study aimed to investigate the relationship of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ...
Marzieh Kazerani +3 more
doaj +1 more source
A point mutation of integrin beta 1 subunit blocks binding of alpha 5 beta 1 to fibronectin and invasin but not recruitment to adhesion plaques. [PDF]
A point mutation in a highly conserved region of the beta 1 subunit, Asp130 to Ala (D130A) substitution, abrogates the Arg-Gly-Asp (RGD)-dependent binding of alpha 5 beta 1 to fibronectin (FN) without disrupting gross structure or heterodimer assembly ...
Ginsberg, MH +4 more
core +2 more sources
Background Although many studies have identified several inflammation-based and/or nutritional markers with prognostic value for patients with various types of cancer, the optimal markers and cut-off values for these markers remain obscure.
Takahiro Toyokawa +9 more
doaj +1 more source
Chapter Five. Systematic review results by biomarker classifications [PDF]
5.1 Markers of Absorption and Permeability Overview 5.2 Markers of Absorption 5.3 Markers of Permeability 5.4 Markers of Digestion 5.5 Markers of Intestinal Inflammation and Intestinal Immune Activation 5.6 Markers of Systemic Inflammation and Systemic ...
Denno, Donna M +4 more
core +1 more source
Characterization of potential biomarkers of reactogenicity of licensed antiviral vaccines: randomized controlled clinical trials conducted by the BIOVACSAFE consortium [PDF]
Funding text The authors are grateful for the vital contributions of the participating study volunteers, clinicians, nurses, and laboratory technicians at the Surrey study site.
Bodinham, C. +16 more
core +1 more source
Missense mutations in the perforin (PRF1) gene as a cause of hereditary cancer predisposition [PDF]
Perforin, a pore-forming toxin released from secretory granules of NK cells and CTLs, is essential for their cytotoxic activity against infected or cancerous target cells.
Chaudhry, MS +7 more
core +1 more source
Objective: Neutrophil-to-lymphocyte and lymphocyte-to-C-reactive protein ratios are important prognostic indicators for disease severity measurement among coronavirus patients. To predict the disease severity, CURB-65 scores, and outcome after 14 days of admission using two proxy biomarkers (neutrophil lymphocyte and lymphocyte C-reactive protein ...
Anum Afsar +5 more
openaire +1 more source
Objective Staphylococcus aureus causes infections ranging from mild skin conditions to life-threatening diseases such as endocarditis. The incidence of S.
Yeliz Özdemir +5 more
doaj +1 more source
Inflammation targets specific organs for cancer in carriers of BRCA1/2 pathway mutations [PDF]
Women who inherit a defective BRCA1 or BRCA2 gene have risks for breast/ovarian cancer that are so high and apparently so selective that many mutation carriers choose to have the most likely targets for cancer surgically removed.
Bernard Friedenson
core +1 more source

