Results 181 to 190 of about 1,228,363 (370)

Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting

Advanced Materials, EarlyView.
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu, Won Joon Kim, Hyunjin Lee, Xiaoping Bao, Pilnam Kim   +4 more
wiley   +1 more source

Human Lymphocyte Membrane (HL-A) Alloantigens: Isolation, Purification and Properties [PDF]

, 1969
Dean L. Mann, G. Nicholas Rogentine, John L. Fahey, Stanley G. Nathenson   +3 more
openalex   +1 more source

Carbon Dot‐Linked Hydrogel for TAMs Transform: Spatiotemporal Manipulation to Reshape Tumor Microenvironment

Advanced Materials, EarlyView.
The CDs crosslinked egg white hydrogel loaded with lipopolysaccharide (LPS) and CA170 (TTF‐L‐C) can realize spatiotemporal tumor‐associated macrophages (TAMs) transformation from multi‐level dimensions, including spatial recruitment, cell phenotype reprogramming, and immune checkpoint molecule blockade.
Lingyun Li, Jun Wu, Xue Wu, Zhenjian Li, Xianming Zhang, Zekun Yan, Yingqi Liang, Caishi Huang, Songnan Qu   +8 more
wiley   +1 more source

Impaired Lymphocyte Transformation in Ataxia-Telangiectasia in Part Due to a Plasma Inhibitory Factor [PDF]

, 1969
Dale E. McFarlin, Joost J. Oppenheim
openalex   +1 more source

Bee Better: The Role of Honey in Modern Wound Care

Advanced Therapeutics, EarlyView.
The use of honey as a wound care agent is controversial but paradoxically increasingly popular. Honey possesses relevant antimicrobial properties and can modulate the immune system. The wound healing properties of honey likely depend on its composition and varies across wound types.
Léo‐Paul Tricou, Natalie Guirguis, Sarah Djebbar, Benjamin R. Freedman, Simon Matoori   +4 more
wiley   +1 more source

Studies of Lymphocyte Culture: Products of Sensitive Lymphocyte-Antigen Interaction [PDF]

, 1969
Lynn E. S̄pitler, H. Sherwood Lawrence
openalex   +1 more source

Autologous Peripheral Vγ9Vδ2 T Cell Synergizes with αβ T Cell Through Antigen Presentation and BTN3A1 Blockade in Immunotherapy of Cervical Cancer

Advanced Science, EarlyView.
This study provides proof‐of‐concept evidence showing that through direct killing, antigen presentation, and competitively binding to BTN3A1, Vγ9Vδ2 T cells amplified from cervical cancer (CC) patients can synergize with αβ T cells to exert anti‐CC function both in vitro and in vivo.
Min Wu, Jian Liu, Liting Liu, Yifan Yang, Hong Liu, Long Yu, Haihong Zeng, Shuo Yuan, Ruiyi Xu, Hangyu Liu, Han Jiang, Shen Qu, Liming Wang, Ying Chen, Jingyu Wang, Yuwei Zhang, Shan He, Ling Feng, Junyan Han, Wanjiang Zeng, Hui Wang, Yafei Huang   +21 more
wiley   +1 more source

Mediation of Delayed Hypersensitivity by Peripheral Blood Lymphocytes in Vitro and by Their Products in Vivo and in Vitro, Morphology of in Vitro Lymphocyte-Macrophage Interaction [PDF]

, 1968
Harry Bartfeld, Robert L. Kelly
openalex   +1 more source

Metabolic‐Immune Suppression Mediated by the SIRT1‐CX3CL1 Axis Induces Functional Enhancement of Regulatory T Cells in Colorectal Carcinoma

Advanced Science, EarlyView.
This study discovers that SIRT1, a hub gene involved in glucolipid metabolic conversion in colorectal carcinoma (CRC), stimulates CX3CL1 secretion in CRC cells by activating FOXO1. The CX3CL1‐CX3CR1 signaling promotes the differentiation of TCF7+ regulatory T cells (Tregs) into an enhanced immunosuppressive TNFRSF9+ Treg phenotype.
Ruiyang Zi, Xiang Zhao, Limei Liu, Yijie Wang, Rui Zhang, Zhiheng Bian, Haoran Jiang, Taorui Liu, Yixin Sun, Han Peng, Xuesong Wang, Fanghao Lu, Chao Zhang, Fan Zhang, Qing Qin, Houjie Liang, Jianjun Li, Zhihao Wei, Yan Dong   +18 more
wiley   +1 more source

PROTECTION EXPERIMENTS AGAINST RADIATION INJURY WITH LYMPHOCYTES

, 1952
Iain L. Campbell, Merrill Ross
openalex   +2 more sources