Results 191 to 200 of about 935,381 (311)

Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in primary versus secondary premature ejaculation: a comparative study. [PDF]

Basic Clin Androl
Aldemir N, Üntan İ.
europepmc   +1 more source

Generation of effector cells from T cell subsets [PDF]

, 1979
Koszinowski, Ulrich H., Simon, M. M.
core  

Promoting Treg Polarization‐Mediated Anti‐Scar and Appendage Regeneration in Wound Healing

Advanced Science, EarlyView.
This study develops a PLGA@LA‐BMP4‐PG bilayer scaffold to address scar formation and appendage loss in skin repair. The piezoelectric PLA layer enhances cell migration via electric fields, while GelMA delivers LA promoting Tregs polarization and BMP4 inhibiting FBs differentiation.
Yiwen Yang, Mingjie Kuang, Jiacheng Shi, Ruiyan Li, Yuhan Zhang, Xinting Liu, Runtan Li, Yong Kang, Bin Yao, Shuquan Zhang, Xiaoyuan Ji   +10 more
wiley   +1 more source

Integrating serum ferritin and neutrophil-to-lymphocyte ratio with Sequential Organ Failure Assessment score improves mortality prediction in sepsis. [PDF]

World J Methodol
Patel N, Patel V, Murugan Y, Patel K, Varma V, Surani S.   +5 more
europepmc   +1 more source

Gαi1/3 Is a Novel Regulatory Target for RANKL Signal Transduction and Osteoporosis

Advanced Science, EarlyView.
ABSTRACT Osteoporosis, characterized by progressive bone loss and increased fracture risk, is a growing concern as the population ages. Current treatments, though advanced, remain limited, underscoring the necessity for novel therapeutic targets. Recent studies have shown that the immune system plays a key role in osteoporosis, with osteoclasts driving
Chaowen Bai, Mingchao Zhang, Le Liu, Lide Tao, Chenyang Xu, Hao Chai, Xin Shi, Yin Wang, Xiaopei Zhang, Qiong Chen, Dong Liu, Jinyu Bai, Chang She, Xiaozhong Zhou, Cong Cao, Huajian Shan   +15 more
wiley   +1 more source

Diagnostic value of cellular inflammatory markers in CNS tumor patients undergoing glucocorticoid therapy. [PDF]

Front Oncol
Sklyar S, Sitovskaya D, Dryagina N, Ulitin A, Olyushin V, Combs SE, Samochernykh K, Shevtsov M.   +7 more
europepmc   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Prognostic Role of Inflammatory Blood Cell Ratios in Glioblastoma Patients: Insights from a Single-institution Study. [PDF]

In Vivo
Lucarelli M, Desiderio C, DE Pasquale G, Bonelli R, Augurio A, Vinciguerra A, Trignani M, Nuzzo M, Pilla AD, Taraborrelli M, DI Tommaso M, Rosa C, DI Nicola M, D'Aviero A, Genovesi D.   +14 more
europepmc   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Assessment of pan-immune-inflammation value as a novel marker of proliferative diabetic retinopathy stage. [PDF]

Int J Ophthalmol
Candan O, Orman G, Ünlü N, Uney G.
europepmc   +1 more source