Results 281 to 290 of about 333,907 (356)

Effect of Hemoglobin, Albumin, Lymphocyte Count, and Platelet (HALP) Score on Survival of Patients with Metastatic Thyroid Cancer Treated with Tyrosine Kinase Inhibitors. [PDF]

J Clin Med
Öztop H, Hunutlu FÇ, Ekizoğlu Sİ, Gül ÖÖ, Cander S, Şahin AB.   +5 more
europepmc   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Transient lymphocyte count decrease correlates with oncolytic adenovirus efficacy in humans: mechanistic and biomarker findings from TUNIMO phase I trial. [PDF]

J Immunother Cancer
Pakola SA, Clubb JHA, Kudling TV, van der Heijden M, Jirovec E, Arias V, Haybout L, Peltola K, Alanko T, Sormunen J, Pellinen T, Taipale K, Quixabeira DCA, Kistler C, Havunen R, Sorsa S, Santos JM, Cervera-Carrascon V, Hemminki A.   +18 more
europepmc   +1 more source

Absolute Lymphocyte Count At Day 30 Predicts Survival In Recipients Of A T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

, 2009
Judith D. Goldberg, Kuan-Chi Lai, Ann A. Jakubowski, Juliet N. Barker, Farid Boulad, Hugo Castro‐Malaspina, Katharine C. Hsu, Nancy A. Kernan, R J O'Reilly, Evangelos Papadopoulos, Susan E. Prockop, Andromachi Scaradavou, Trudy N. Small, Marcel R.M. van den Brink, James W. Young, Glenn Heller, Miguel‐Angel Perales   +16 more
openalex   +1 more source

A Microbiota‐ and IL‐15‐Dependent Innate‐Like B Cell Progenitor Expressing E4BP4

Advanced Science, EarlyView.
This work identifies CD3.NKp46.CD19.NK1.1. NK‐B cells enriched in PDK1‐deficient yet present in wild‐type bone marrow. IL‐15 (via CD122) and TLR9‐microbiota signaling maintain their E4BP4 expression. These cells demonstrate innate immunity, preferentially differentiate into B cells, and unveil a novel microbiota‐ and IL‐15‐dependent regulatory pathway ...
Junming He, Xinlei Hou, Xiaomei Feng, Yayun Dong, Mengqi Ren, Surong Deng, Xinru Yang, Donglin Chen, Lingna Zhao, Shasha Chen, Meixiang Yang, Zhongjun Dong   +11 more
wiley   +1 more source

The preparation and testing of horse antidog and antihuman antilymphoid plasma or serum and its protein fractions. [PDF]

, 1967
Amend, JR, Iwasaki, Y, Marchioro, TL, Porter, KA, Starzl, TE, Zühlke, V   +5 more
core  

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

The Protective Effect of the Crosstalk between Zinc Hair Concentration and Lymphocyte Count-Preliminary Report. [PDF]

Life (Basel)
Urbanowicz T, Hanć A, Tomczak J, Michalak M, Olasińska-Wiśniewska A, Rzesoś P, Szot M, Filipiak KJ, Krasińska B, Krasiński Z, Tykarski A, Jemielity M.   +11 more
europepmc   +1 more source

Efferocytosis‐Driven Polyamine Metabolism in Macrophages Enhances Cancer Stem Cell Enrichment after Chemotherapy in Ovarian Cancer

Advanced Science, EarlyView.
Chemotherapy‐induced efferocytosis drives ovarian cancer stem cell enrichment. By engulfing apoptotic cancer cells, macrophages upregulate ODC1 and produce putrescine, which elevates osteopontin (OPN) expression. Secreted OPN then activates the CD44 receptor on cancer cells, promoting stemness and chemoresistance.
Wenhan Li, Feiquan Ying, Xinkai Pang, Qiulei Wu, Guoqing Li, Lin Huang, Jiayu Xin, Xiaoli Liu, Pan Liu, Xiaohan Xu, Shuran Tan, Yumei Gao, Tong Liu, Si Sun, Xiaoman Wang, Yiping Wen, Liqiong Cai, Shi Du, Yuan Zhang, Jing Cai   +19 more
wiley   +1 more source

METTL5 Enables Immune Evasion of Liver Cancer via Chemokine mRNA Translation Regulation

Advanced Science, EarlyView.
METTL5 reshapes the tumor immune microenvironment through ribosome 18S rRNA m6A modification to regulate the translation of chemokine mRNA. Targeting METTL5‐mediated immunosuppression unleashes anti‐tumor immunity and improves the efficacy of anti‐PD‐1 therapy.
Shuang Li, Xiao Zhao, Tongtong Song, Qiaoyi Chen, Yanqing Wu, Yuting Zhang, Jingying Chen, Yifan Wu, Bin Li, Xinyue Zhang, Zihao Dai, Lixia Xu, Yubin Xie, Alfred Sze‐Lok Cheng, Jianping Guo, Ming Kuang, Shuibin Lin, Zhenwei Peng, Sui Peng, Xuezhen Zeng   +19 more
wiley   +1 more source