Results 61 to 70 of about 328,983 (310)

Investigation of Laboratory Parameters That Differentiate Complicated Appendicitis from Simple Appendicitis in Adults

İstanbul Medical Journal, 2019
Introduction:Acute appendicitis is one of the most common abdominal emergencies. In this study, we aimed to investigate preoperative laboratory parameters in patients with simple and complicated appendicitis.Methods:The medical records of patients over ...
Özgür Dikme, Özlem Dikme
doaj   +1 more source

Age-related changes in blood lymphocyte subsets of south Indian children [PDF]

, 2003
Background. Enumeration of lymphocyte subsets has been widely used for the diagnosis and monitoring of several haematological and immunological disorders.
Arunkumar, N, Hanna, L E, Raja, Alamelu, Sankaran, K, Swaminathan, Soumya   +4 more
core  

Immune compromise in HIV-1/HTLV-1 coinfection with paradoxical resolution of CD4 lymphocytosis during antiretroviral therapy: a case report [PDF]

, 2015
Human immunodeficiency virus type-1 (HIV-1) and human T lymphotropic virus type-1 (HTLV-1) infections have complex effects on adaptive immunity, with specific tropism for, but contrasting effects on, CD4 T lymphocytes: depletion with HIV-1, proliferation
Bangham, C, Basnayake, S, Cook, L, Kagdi, H, Pozniak, A, Rockwood, N, Taylor, GP   +6 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Lymphocyte levels in Crohn’s disease patients in clinical remission are significantly lower than those in healthy people

European Journal of Medical Research
Background and purpose Inflammatory bowel disease (IBD) is a chronic, non-specific inflammatory bowel disease caused by multiple causes. Lymphocytes migration is involved in the pathogenesis of IBD. The purpose of this study was to evaluate whether there
Asi He, Tulan Hu, Linzhen Li
doaj   +1 more source

Evaluation of inflammatory and hematological parameters in patients diagnosed with COVID-19

Journal of Infection in Developing Countries, 2022
Introduction: This study aims to research the effects of hematological and inflammatory parameters on the prognosis of COVID-19 disease and hospitalization duration.
Çiğdem Mermutluoğlu, Recep Dursun, Fesih Aktar, Saim Dayan, Mustafa Kemal Çelen, Ali Kemal Kadiroğlu, Erdal İnci, Rengin Karagöz, Mahir Kuyumcu, Nida Özcan, Recep Tekin   +10 more
doaj   +1 more source

B-cell Prolymphocytic Leukemia in a Young Male [PDF]

, 2011
B-cell prolymphocytic leukemia [B-PLL] is a neoplasm of B prolymphocytes affecting the peripheral blood, bone marrow and spleen. The principal disease characteristics are massive splenomegaly with absent or minimal peripheral lymphadenopathy and a ...
Fernandes, H, Jayaprakash, C, Pailoor, K, Swethadri, GK   +3 more
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

National Institute of Health Stroke Scale Score Mediated the Relationship between Systemic Inflammatory Response Index, High-Sensitivity C-Reactive Protein, and Functional Prognosis of Acute Ischemic Stroke: A Prospective Cross-Sectional Study

Heart and Mind
Background: The systemic inflammatory indicators were reported to relate to the functional prognosis of acute ischemic stroke (AIS). Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic immune-inflammation index (SII ...
Xueqing Liu, Tong Zhang, Liqin Yang, Guojuan Chen, Peng Ding, Delin Yu, Haibing Liao, Jing Liu, Wei Yue   +8 more
doaj   +1 more source

Early decrease in blood lymphocyte count is associated with poor prognosis in COVID-19 patients: a retrospective cohort study

BMC Pulmonary Medicine, 2023
Background Previous studies have declared that baseline lymphocyte count is associated with COVID-19-related death. However, whether dynamic lymphocyte change over time affects prognosis in COVID-19 patients is unknown. This study aims to investigate the
Gong Chen, Xiaofang Zhao, Xinglin Chen, Chengyun Liu   +3 more
doaj   +1 more source