Results 51 to 60 of about 245,801 (303)
Average Values of Neutrophil Lymphocyte Ratio among a Representative Sample of Adult Population in a Tertiary Care Teaching Hospital [PDF]
National Journal of Laboratory Medicine, 2018 Introduction: Several studies have been conducted over the years for a simple, reliable, cost effective investigation to know the intensity of systemic inflammation in patients suffering from shock, major surgery, sepsis, cancers, thromboembolic ...
Ranjeeta Sadashiv Banakar, Rashmi Verma
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Risk factors for wound infection in surgery for spinal metastasis
, 2015 Wound infection rates are generally higher in patients undergoing surgery for spinal metastasis. Risk factors of wound infection in these patients are poorly understood.
Popta, D. +20 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
International Journal of Hematology-Oncology and Stem Cell Research, 2023 Background: Since 2019, Coronavirus has been a highly contagious disease. The COVID-19 outbreak was declared a pandemic by the World Health Organization in March 2020.
Farhad Shahi +6 more
doaj
Abnormal peripheral blood cell counts in neurofibromatosis type 1
Scientific Reports, 2022 Neurofibromatosis type 1 (NF1), also known as von Recklinghausen disease, is an autosomal dominant disease characterized by neurofibromas with infiltration of mast cells.
Yoshimasa Nobeyama +2 more
doaj +1 more source
Changes of lymphocyte blood count.
, 2018 Black line with black circles shows patients’ lymphocyte counts with postoperative pneumonia. The dotted line with white triangles shows patients’ lymphocyte count with no postoperative pneumonia.
Guillaume Monneret (329582) +7 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
European Journal of Medical ResearchBackground and purpose Inflammatory bowel disease (IBD) is a chronic, non-specific inflammatory bowel disease caused by multiple causes. Lymphocytes migration is involved in the pathogenesis of IBD. The purpose of this study was to evaluate whether there
Asi He, Tulan Hu, Linzhen Li
doaj +1 more source