Results 51 to 60 of about 1,450,283 (404)

Cell surface Glut1 levels distinguish human CD4 and CD8 T lymphocyte subsets with distinct effector functions

Scientific Reports, 2016
CD4 and CD8 T lymphocyte activation requires the generation of sufficient energy to support new biosynthetic demands. Following T cell receptor (TCR) engagement, these requirements are met by an increased glycolysis, due, at least in part, to induction ...
Gaspard Cretenet, I. Clerc, M. Matias, S. Loisel, Marco Craveiro, Leal Oburoglu, S. Kinet, Cédric Mongellaz, V. Dardalhon, N. Taylor   +9 more
semanticscholar   +1 more source

IFN-γ-stimulated neutrophils suppress lymphocyte proliferation through expression of PD-L1. [PDF]

PLoS ONE, 2013
During systemic inflammation different neutrophil subsets are mobilized to the peripheral blood. These neutrophil subsets can be distinguished from normal circulating neutrophils (CD16(bright)/CD62L(bright)), based on either an immature CD16(dim)/CD62L ...
Stan de Kleijn, Jeroen D Langereis, Jenneke Leentjens, Matthijs Kox, Mihai G Netea, Leo Koenderman, Gerben Ferwerda, Peter Pickkers, Peter W M Hermans   +8 more
doaj   +1 more source

Effects of Selected Prebiotics or Synbiotics Administered in ovo on Lymphocyte Subsets in Bursa of the Fabricius, Thymus, and Spleen in Non-Immunized and Immunized Chicken Broilers

Animals, 2021
The effects of in ovo-delivered prebiotics and synbiotics on the lymphocyte subsets of the lymphoid organs in non-immunized 7-day-old broiler chickens and in non-immunized, sheep red blood cells (SRBC)-immunized, and dextran (DEX)-immunized 21- and 35 ...
Marianna Szczypka, Agnieszka Suszko-Pawłowska, Maciej Kuczkowski, Michał Gorczykowski, Magdalena Lis, Artur Kowalczyk, Ewa Łukaszewicz, Dominik Poradowski, Iwona Zbyryt, Marek Bednarczyk, Tadeusz Stefaniak   +10 more
doaj   +1 more source

Impact of aging : sporadic, and genetic risk factors on vulnerability to apoptosis in Alzheimer's disease [PDF]

, 2003
The identification of specific genetic (presenilin-1 [PS1] and amyloid precursor protein [APP] mutations) and environmental factors responsible for Alzheimer's disease (AD) has revealed evidence for a shared pathway of neuronal death.
Czech, Christian, Eckert, Anne, Frölich, Lutz, Kratzsch, Tilmann, Leutner, Silke, Maurer, Konrad, Müller, Walter E., Peters, Jürgen, Pradier, Laurent, Schindowski, Katharina, Steiner, Barbara, Touchet, Natalie   +11 more
core   +1 more source

Capillary blood as an alternative specimen for enumeration of percentages of lymphocyte subsets

BMC Research Notes, 2019
Objective Capillary blood has been increasingly used in point-of-care setting for clinical monitoring in immunology and infectious diseases. We explored whether percentages of lymphocyte subsets (T-cells; CD3+, helper T-cells; CD4+, cytotoxic T-cells ...
Supanart Srisala, Nutkridta Pongsakul, Thiantip Sahakijpicharn, Suradej Hongeng, Somchai Chutipongtanate, Nopporn Apiwattanakul   +5 more
doaj   +1 more source

A thermodynamical perspective of immune capabilities [PDF]

Journal of Theoretical Biology 287 (2011) 48-63, 2011
We consider the mutual interactions, via cytokine exchanges, among helper lymphocytes, B lymphocytes and killer lymphocytes, and we model them as a unique system by means of a tripartite network. Each part includes all the different clones of the same lymphatic subpopulation, whose couplings to the others are either excitatory or inhibitory (mirroring ...
arxiv   +1 more source

Dysregulation of Chemokine/Chemokine Receptor Axes and NK Cell Tissue Localization during Diseases. [PDF]

, 2016
Chemokines are small chemotactic molecules that play key roles in physiological and pathological conditions. Upon signaling via their specific receptors, chemokines regulate tissue mobilization and trafficking of a wide array of immune cells, including ...
Ali, Allegretti, Balabanian, Berahovich, Bernardini, Bernardini, Bielekova, Bolomsky, Bradfield, Broxmeyer, Burga, Calderon, Campbell, Campbell, Carlsten, Carrega, Carrega, Castriconi, Chan, Chiossone, Chuang, Clift, Contento, Cooper, Doncker, Eisenhardt, El-Sherbiny, Fehniger, Foxman, Gajewski, Gao, Gomez-Mouton, Gregoire, Gulino, Halama, Hanna, Hayakawa, Huntington, Huntington, Inngjerdingen, Ishibashi, Ju, Juelke, Kastrukoff, Kramp, Krug, Krumbholz, Lanier, Lode, Lopez-Verges, Lunemann, Mace, Maciejewski-Duval, Mailliard, Mantovani, Marcenaro, Marquardt, Martin, Martin-Fontecha, Martinez-Rodriguez, Mayol, Moustaki, Muller, Nagasawa, Nakashima, Nokihara, Ottaviani, Ouyang, O’Boyle, Pablos, Pachynski, Pak-Wittel, Parolini, Paust, Petit, Ponzetta, Ponzetta, Riva, Rodriguez-Martin, Romagnani, Sciume, Sechler, Serrano-Pertierra, Shimoda, Sohy, Sojka, Somanchi, Stabile, Stegmann, Stumm, Szpurka, Tham, Vanbervliet, Vandenbark, Vischer, Vitale, Watt, Watts, Wendel, Yokoyama, Zabel, Zlotnik   +101 more
core   +1 more source

T Helper Lymphocyte Subsets and Plasticity in Autoimmunity and Cancer: An Overview

BioMed Research International, 2015
In response to cytokine signalling and other factors, CD4-positive T lymphocytes differentiate into distinct populations that are characterized by the production of certain cytokines and are controlled by different master transcription factors.
E. Ivanova, A. Orekhov
semanticscholar   +1 more source

Characteristics of Peripheral Lymphocyte Subset Alteration in COVID-19 Pneumonia

Journal of Infectious Diseases, 2020
Background In December 2019, novel coronavirus (SARS-CoV-2) pneumonia (COVID-19) was reported in Wuhan and has since rapidly spread throughout China.
Fan Wang, Jia-yan Nie, Haizhou Wang, Qiu Zhao, Yong Xiong, Liping Deng, Shi-hui Song, Zhiyong Ma, Pingzheng Mo, Yongxi Zhang   +9 more
semanticscholar   +1 more source

Antigen-specific electrophoretic cell separation for immunological investigations [PDF]

, 1989
Preincubation of human blood lymphocytes with cell surface antigen specific antibodies under non-capping conditions reduces the electrophoretic mobility of the corresponding lymphocyte subpopulation.
Hannig, K., Hansen, Ernil, Wustrow, T. P.   +2 more
core   +1 more source