Results 81 to 90 of about 1,450,283 (404)

Changes in lymphocyte subsets in patients with Guillain-Barré syndrome treated with immunoglobulin

BMC Neurology, 2014
BackgroundGuillain-Barré syndrome (GBS) is an autoimmune condition characterized by peripheral neuropathy. The pathogenesis of GBS is not fully understood, and the mechanism of how intravenous immunoglobulin (IVIG) cures GBS is ambiguous.
Huiqing Hou, Jun Miao, Xuedan Feng, Mei Han, Xiujuan Song, Li Guo   +5 more
semanticscholar   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Comparison of low density lipoprotein uptake by different human lymphocyte subsets: a new method using double-fluorescence staining.

Journal of Lipid Research, 1996
A method to determine low density lipoprotein (LDL) uptake of distinct lymphocyte subpopulations was developed using fluorescent LDL and subsequent staining of lymphocyte subsets with biotinylated monoclonal antibodies plus streptavidin-CyChrome.
C Maczek, H Recheis, G Böck, T Stulnig, G Jürgens, G Wick   +5 more
doaj  

Changes of peripheral blood lymphocyte subsets in patients with psoriasis [PDF]

Jichu yixue yu linchuang, 2021
Objective To investigate the changes and immune mechanisms of peripheral blood lymphocyte subsets in psoriasis patients with progressive, stationary and regression stages.
LIU Yan-min, ZHAO Xin-cheng, LI Jun-qin, ZHANG Kai-ming
doaj  

CD98hc facilitates B cell proliferation and adaptive humoral immunity. [PDF]

, 2009
The proliferation of antigen-specific lymphocytes and resulting clonal expansion are essential for adaptive immunity. We report here that B cell-specific deletion of the heavy chain of CD98 (CD98hc) resulted in lower antibody responses due to total ...
A Mondino, AP Warren, AW Freidman, C Brakebusch, CA Fenczik, CA Fenczik, CC Feral, CC Feral, Cecille D Browne, CG Lo, CG Proud, Chloé C Féral, CL Abram, D Torrents, DC Otero, DE White, DM Rose, E Arana, F Esteban, FD Batista, FM Burnet, GW Prager, H Tsumura, J Bertran, J Fernandez-Herrera, J Hasbold, JG Cyster, JH Kehrl, JL Walker, Joseph Cantor, K Hara, K Roovers, KB Lin, KL Wolniak, L Kass, L Van Parijs, LA Diaz Jr., MA Schwartz, Mark H Ginsberg, MD Cooper, ML Motti, NC Henderson, R Zent, Raphael Ruppert, RC Rickert, Reinhard Fässler, RK Assoian, RO Hynes, Robert C Rickert, RT Abraham, SG Tangye, SJ Fleire, T Lammermann, T Uinuk-Ool, TN Sims, TT Lu, Y Shimizu   +56 more
core   +2 more sources

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Dynamic surveillance of lymphocyte subsets in patients with non-small cell lung cancer during chemotherapy or combination immunotherapy for early prediction of efficacy

Frontiers in Immunology
BackgroundNon-small cell lung cancer (NSCLC) remains the leading cause of cancer-related deaths worldwide. Lymphocytes are the primary executors of the immune system and play essential roles in tumorigenesis and development.
Shanshan Zhen, Shanshan Zhen, Wenqian Wang, Wenqian Wang, Guohui Qin, Taiying Lu, Li Yang, Li Yang, Li Yang, Yi Zhang, Yi Zhang, Yi Zhang   +11 more
doaj   +1 more source

Characteristics of lymphocyte subsets and cytokine profiles of patients with COVID-19

Virology Journal, 2022
Background Abnormalities of lymphocyte subsets and cytokine profiles have been observed in most patients with coronavirus disease (COVID-19). Here, we explore the role of lymphocyte subsets and cytokines on hospital admission in predicting the severity ...
Pengfei Pan, Xinxin Du, Qilong Zhou, Yong Cui, Xiaochun Deng, Chao Liu, Zongjun Hu, Jianguo Chen, Xiangyou Yu, Weihua Shi   +9 more
doaj   +1 more source

Air Pollution and Lymphocyte Phenotype Proportions in Cord Blood [PDF]

, 2005
Effects of air pollution on morbidity and mortality may be mediated by alterations in immune competence. In this study we examined short-term associations of air pollution exposures with lymphocyte immunophenotypes in cord blood among 1,397 deliveries in
Caroline E.W. Herr, DiFranza JR, D’Arena G, Garcia LA, Harris D, Irva Hertz-Picciotto, Jesse P. Joad, Kent E. Pinkerton, Michael Lipsett, Miroslav Dostál, Paul Ashwood, Perera F, Poh-Sin Yap, Radim J. Šrám, Robert H. Shumway, Santagostino A   +15 more
core   +2 more sources

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source