Results 91 to 100 of about 432,153 (300)

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source

Investigation of Lymphocyte Subsets in Peripheral Blood of Patients with Dyslipidemia

International Journal of General Medicine, 2021
Da-Ming Xu,1,* Qian Li,2,* Jing-Xing Yi,3,* Xin-Jian Cai,3 Long Xie,3 Wei Fang,3 Jin-Feng Qiu,4 Cheng-Wei Xu,5 Chun-Ling He,6 Xian-Ru Xu,7 Jie-Song Xu,8 Jun Yin2,3 1Division of Urological Surgery, Second Affiliated Hospital of Shantou ...
Xu DM, Li Q, Yi JX, Cai XJ, Xie L, Fang W, Qiu JF, Xu CW, He CL, Xu XR, Xu JS, Yin J   +11 more
doaj  

Longitudinal analysis of lymphocyte subsets in M04203.

, 2018
The absolute number of cells in lymphocyte subsets was determined from the blood samples in the experimental infection of M04103 shown in Fig 5.
Serge Barcy (129971), Helle Bielefeldt-Ohmann (129968), Minako Ikoma (4843458), Kellie Howard (3586490), A. Gregory Bruce (129965), Jeannette Staheli (5982809), Timothy M. Rose (129984)   +6 more
core   +1 more source

A 3D Human Bone and Bone Marrow‐on‐a‐Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance

Advanced Science, EarlyView.
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer, Melanie‐Jasmin Ort, Kristian Händler, Emely Bortel, Ioanna Maria Dimitriou, Martin Textor, Georg N. Duda, Janosch Schoon, Uwe Marx, Uwe Kornak, Annika Winter, Bernhard Hesse, Stefanie Donner, Sebastian Hardt, Oliver Klein, Simon Reinke, Malte Spielmann, Sven Geißler   +17 more
wiley   +1 more source

Additional file 1 of Association between body fat distribution and B-lymphocyte subsets in peripheral blood

, 2023
Supplementary Fig. 1: Association between visceral fat, respectively waist-to-height ratio, and relative frequencies of B lymphocyte subsets (ungated). Supplementary Fig.
Dennis Freuer (5049107), Timo Schmitz (12342088), Jakob Linseisen (123573), Pia Prechtl (16981565), Christa Meisinger (39940), Nicole Pochert (16981568), Claudia Traidl-Hoffmann (487601)   +6 more
core   +1 more source

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source

Lymphocytes and immunoglobulins in peripheral blood and lymphatic fluid of neonates with chylothorax

Frontiers in Immunology
BackgroundNeonatal chylothorax is associated with high morbidity and mortality, partly due to increased infection risk from lymphocyte depletion and hypogammaglobulinemia. However, data specific to chylothorax cohorts are limited.
Domenico Umberto De Rose, Francesca Landolfo, Flaminia Pugnaloni, Fatima Zahra Gassabi, Ludovica Martini, Alessandra Santisi, Claudia Columbo, Paola Giliberti, Fabia Gazzotti, Ottavia Porzio, Ottavia Porzio, Claudia Capponi, Carlo Federico Perno, Maria Paola Ronchetti, Andrea Conforti, Guglielmo Salvatori, Irma Capolupo, Andrea Dotta   +17 more
doaj   +1 more source

Measurement of proliferation and disappearance of rapid turnover cell populations in human studies using deuterium-labeled glucose.

, 2009
Cell proliferation may be measured in vivo by quantifying DNA synthesis with isotopically labeled deoxyribonucleotide precursors. Deuterium-labeled glucose is one such precursor which, because it achieves high levels of enrichment for a short period, is ...
Defoiche, Julien, Macallan, DC, de Lara, C, Asquith, B, Macallan, Derek C, Beverley, Peter, Beverley, Peter CL, Zhang, Y, Ghattas, H, Hala Ghattas, Becca Asquith, Defoiche, J, de Lara, Catherine, Asquith, Becca, Julien Defoiche, Derek C Macallan, Ghattas, Hala, Yan Zhang, Peter C L Beverley, Catherine de Lara, Zhang, Yan   +20 more
core   +1 more source

Reference ranges of lymphocyte subsets in healthy Qatari adults [PDF]

, 2015
Aim: Determine reference ranges of lymphocyte subsets in healthy Qatari adults. Patients & Methods: Blood samples (n = 150) were investigated using four colors flow cytometery. Results: The mean percentage and absolute values of the lymphocyte subsets
Sharafeldin, Hend, Al-Marwani, Asma, Alnaqdy, Adel, Al-Thani, Asma, Saleem, Wedad H   +4 more
core   +1 more source

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source