Results 91 to 100 of about 213,374 (313)

Specific dynamic variations in the peripheral blood lymphocyte subsets in COVID-19 and severe influenza A patients: a retrospective observational study

BMC Infectious Diseases, 2020
Background Both COVID-19 and influenza A contribute to increased mortality among the elderly and those with existing comorbidities. Changes in the underlying immune mechanisms determine patient prognosis.
Fang Qian, Guiju Gao, Yangzi Song, Yanli Xu, Aibin Wang, Sa Wang, Yiwei Hao, Meiling Chen, Xiaoyang Ma, Tianwei Zhao, Xiaodi Guo, Zhihai Chen, Fujie Zhang   +12 more
doaj   +1 more source

Age-related impairment of human T lymphocytes' activation: specific differences between CD4+ and CD8+ subsets [PDF]

, 2006
The relevance of physiological immune aging is of great interest with respect to determining disorders with pathologic immune function in aging individuals.
Eckert, Anne, Fröhlich, Lutz, Maurer, Konrad, Müller, Walter E., Schindowski, Katharina   +4 more
core  

Myocardial aging as a T-cell–mediated phenomenon [PDF]

, 2017
In recent years, the myocardium has been rediscovered under the lenses of immunology, and lymphocytes have been implicated in the pathogenesis of cardiomyopathies with different etiologies.
Abeßer, Marco, Beyersdorf, Niklas, Burkard, Matthias, Frantz, Stefan, Friedrich, Mike, Heinze, Katrin G., Hofmann, Ulrich, Jocelyne, Demengeot, Kerkau, Thomas, Nunes-Silva, Vânia, Peters, Laura, Pinnecker, Jürgen, Ramos, Gustavo Campos, Schuh, Kai, van den Berg, Anne, Weirather, Johannes   +15 more
core   +1 more source

Matrix Viscoelasticity Regulates Dendritic Cell Migration and Immune Priming

Advanced Materials, EarlyView.
Matrix viscoelasticity is a key mechanical feature of the tumor microenvironment but remains poorly understood in immune regulation. Here, we develop a tunable collagen platform to decouple viscoelasticity from stiffness and show that slow‐relaxing matrices constrain dendritic cell migration by limiting actomyosin‐driven matrix remodeling, thereby ...
Wei‐Hung Jung, Emie Humann, Joshua M. Price, Yoav Binenbaum, Azra Haseki, Sanjana Iyer, David J. Mooney   +6 more
wiley   +1 more source

Tumor-associated and immunochemotherapy-dependent long-term alterations of the peripheral blood NK cell compartment in DLBCL patients [PDF]

, 2015
Natural Killer (NK) cells are a key component of tumor immunosurveillance and thus play an important role in rituximab-dependent killing of lymphoma cells via an antibody-dependent cellular cytotoxicity (ADCC) mechanism.
Battella, Simone, Cecere, Francesca, DI NAPOLI, Arianna, Eleonora, Alma, LA SCALEIA, Raffaella, M., Christina Cox, Mainiero, Fabrizio, Monarca, Bruno, Palmieri, Gabriella, Pelliccia, Sabrina, Porzia, Alessandra, Ruco, Luigi, Santoni, Angela, Zingoni, Alessandra   +13 more
core   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Investigation of Lymphocyte Subsets in Peripheral Blood of Patients with Dyslipidemia

International Journal of General Medicine, 2021
Da-Ming Xu,1,* Qian Li,2,* Jing-Xing Yi,3,* Xin-Jian Cai,3 Long Xie,3 Wei Fang,3 Jin-Feng Qiu,4 Cheng-Wei Xu,5 Chun-Ling He,6 Xian-Ru Xu,7 Jie-Song Xu,8 Jun Yin2,3 1Division of Urological Surgery, Second Affiliated Hospital of Shantou ...
Xu DM, Li Q, Yi JX, Cai XJ, Xie L, Fang W, Qiu JF, Xu CW, He CL, Xu XR, Xu JS, Yin J   +11 more
doaj  

Features of the immune system response in pediatric renal transplant recipients

Počki, 2019
Background. We need to take into account patients’ age and their immune system status to improve the results of kidney transplantation. Objective: to study the characteristics of the immune system response to a kidney transplant in pediatric recipients ...
V.P. Zakordonets, R.O. Zograbyan, A.S. Voroniak, A.V. Kubashko   +3 more
doaj   +1 more source

Prospective Analysis of Stress and Immunity in Advanced Cancer [PDF]

, 2011
Objectives:The aims of this study were to assess chronic stress in a sample of advanced cancer patients, test the association between stress and NK cell immune markers over time, and examine whether stress predicts immune markers over time.Methods:A ...
Ikpeama, Uzoh Erick
core   +1 more source

A murine intestinal intraepithelial NKp46-negative innate lymphoid cell population characterized by group 1 properties [PDF]

, 2017
The Ly49E receptor is preferentially expressed on murine innate-like lymphocytes, such as epidermal V gamma 3 T cells, intestinal intraepithelial CD8 alpha alpha(+) T lymphocytes, and CD49a(+) liver natural killer (NK) cells.
Biswas, Aindrila, Diefenbach, Andreas, Dunay, Ildiko Rita, Filtjens, Jessica, Gronke, Konrad, Kerre, Tessa, Leclercq, Georges, Martens, Liesbet, Matthys, Patrick, Plum, Jean, Saeys, Yvan, Taghon, Tom, Taveirne, Sylvie, Van Acker, Aline, Van Ammel, Els, Vandekerckhove, Bart   +15 more
core   +2 more sources